499 AN AUDIT TO ASSESS THE EFFICACY OF LIDOCAINE 5% PLASTERS IN PATIENTS WITH ‘MIXED PAIN’ SYNDROMES

2010 ◽  
Vol 4 (S1) ◽  
pp. 141-141
Author(s):  
R. Poddar ◽  
M.E. Bone
Keyword(s):  
2020 ◽  
Vol 11 ◽  
Author(s):  
Susanna Asseyer ◽  
Graham Cooper ◽  
Friedemann Paul

Neuromyelitis optica spectrum disorders (NMOSDs) and myelin oligodendrocyte glycoprotein-antibody-associated disease (MOGAD) are autoimmune inflammatory disorders of the central nervous system (CNS). Pain is highly prevalent and debilitating in NMOSD and MOGAD with a severe impact on quality of life, and there is a critical need for further studies to successfully treat and manage pain in these rare disorders. In NMOSD, pain has a prevalence of over 80%, and pain syndromes include neuropathic, nociceptive, and mixed pain, which can emerge in acute relapse or become chronic during the disease course. The impact of pain in MOGAD has only recently received increased attention, with an estimated prevalence of over 70%. These patients typically experience not only severe headache, retrobulbar pain, and/or pain on eye movement in optic neuritis but also neuropathic and nociceptive pain. Given the high relevance of pain in MOGAD and NMOSD, this article provides a systematic review of the current literature pertaining to pain in both disorders, focusing on the etiology of their respective pain syndromes and their pathophysiological background. Acknowledging the challenge and complexity of diagnosing pain, we also provide a mechanism-based classification of NMOSD- and MOGAD-related pain syndromes and summarize current treatment strategies.


Cancers ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 510 ◽  
Author(s):  
Augusto Caraceni ◽  
Morena Shkodra

More than half of patients affected by cancer experience pain of moderate-to-severe intensity, often in multiple sites, and of different etiologies and underlying mechanisms. The heterogeneity of pain mechanisms is expressed with the fluctuating nature of cancer pain intensity and clinical characteristics. Traditional ways of classifying pain in the cancer population include distinguishing pain etiology, clinical characteristics related to pain and the patient, pathophysiology, and the use of already validated classification systems. Concepts like breakthrough, nociceptive, neuropathic, and mixed pain are very important in the assessment of pain in this population of patients. When dealing with patients affected by cancer pain it is also very important to be familiar to the characteristics of specific pain syndromes that are usually encountered. In this article we review methods presently applied for classifying cancer pain highlighting the importance of an accurate clinical evaluation in providing adequate analgesia to patients.


2008 ◽  
Vol 13 (1) ◽  
pp. 13-18 ◽  
Author(s):  
Massimiliano Aragona ◽  
Lorenzo Tarsitani ◽  
Serena De Nitto ◽  
Maurizio Inghilleri

BACKGROUND: Elevated Minnesota Multiphasic Personality Inventory (MMPI) scores on the hysteria (Hy) scale are reported in several forms of pain. Previous results were possibly biased by diagnostic heterogeneity (psychogenic, somatic and mixed pain syndromes included in the same index sample) or Hy heterogeneity (failure to differentiate Hy scores into clinically meaningful sub-scales, such as admission of symptoms [Ad] and denial of symptoms [Dn]).METHODS: To overcome this drawback, 48 patients diagnosed as having aDiagnostic and Statistical Manual of Mental Disorders, 4thedn, Text Revision (DSM-IV-TR) diagnosis of “pain disorder associated with psychological factors” were compared with 48 patients experiencing somatic pain excluding psychological factors, and 42 somatic controls without pain.RESULTS: MMPI Hy and hypochondriasis (Hs) scores were significantly higher in the pain disorder group than in control groups, who scored similarly. MMPI correction (K) scores and Dn scores were similar in the three groups, whereas Ad was significantly higher in the pain disorder group and lower and similar in the two control groups, respectively. In the pain disorder group, Ad and Dn were negatively correlated, whereas in control groups they were unrelated.CONCLUSIONS: These findings suggest that whereas a pattern of high Hs and Hy scores together with a normal K score might characterize patients with a pain disorder associated with psychological factors, elevated Hy scores per se do not indicate hysterical traits. In the pain disorder group, elevated Hy scores reflected the Ad subscale alone, indicating a strikingly high frequency of distressing somatic symptoms. They tend not to repress or deny the emotional malaise linked to symptoms, as the hysterical construct expects. The pain disorder designation should be considered a nonhysterical form of somatization.


2012 ◽  
Vol 31 (03) ◽  
pp. 147-153 ◽  
Author(s):  
M. Förster ◽  
F. Mahn ◽  
R. Baron

ZusammenfassungDas aktuelle Konzept für chronische Rückenschmerzen postuliert ein Nebeneinander von nozizeptiven und neuropathischen Schmerzkomponenten (Mixed-Pain-Konzept). Die charakteristischen neuropathischen Symptome mit negativen und positiven Phänomenen helfen bei der Diagnosestellung. Durch weitgehend objektive Verfahren wie Bedside-Tests und Fragebögen kann die neuropathische Komponente valide identifiziert werden. Für die therapeutischen Optionen stehen nur Daten für den nozizeptiven Rückenschmerz zur Verfügung. In Anlehnung an klassische neuropathische Schmerzsyndrome versucht man einen Ansatz mit Medikamenten, ohne dass eine spezifische evidenzbasierte Therapie empfohlen werden kann.


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