Transcriptional profiling and network pharmacology analysis identify the potential biomarkers from Chinese herbal formula Huosu Yangwei Formula treated gastric cancer in vivo

2021 ◽  
Vol 19 (12) ◽  
pp. 944-953
Author(s):  
Sheng-Quan FANG ◽  
Yue-Han LIU ◽  
Kun-Peng ZHAO ◽  
Hui-Xing ZHANG ◽  
Hong-Wei WANG ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Transcriptional Profiling ◽  
Network Pharmacology ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Potential Biomarkers

scholarly journals Pharmacokinetic interaction between a Chinese herbal formula Huosu Yangwei oral liquid and apatinib in vitro and in vivo

2020 ◽  
Vol 72 (7) ◽  
pp. 979-989
Author(s):  
Sheng‐Quan Fang ◽  
Jian Huang ◽  
Feng Zhang ◽  
Hong‐Mei Ni ◽  
Qi‐Long Chen ◽  
...  
Keyword(s):  
Pharmacokinetic Interaction ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Oral Liquid

scholarly journals San Wu Huangqin Decoction, a Chinese Herbal Formula, Inhibits Influenza a/PR/8/34 (H1N1) Virus Infection In Vitro and In Vivo

Viruses ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 117 ◽  
Author(s):  
Qinhai Ma ◽  
Qingtian Yu ◽  
Xuefeng Xing ◽  
Sinian Liu ◽  
Chunyu Shi ◽  
...  
Keyword(s):  
Virus Infection ◽  
Influenza A ◽  
H1n1 Virus ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
H1n1 Virus Infection

Jiawei-Yupingfeng-Tang, a Chinese herbal formula, inhibits respiratory viral infections in vitro and in vivo

2013 ◽  
Vol 150 (2) ◽  
pp. 521-528 ◽  
Author(s):  
Qiang Liu ◽  
Li Lu ◽  
Moli Hua ◽  
Yu Xu ◽  
Hairong Xiong ◽  
...  
Keyword(s):  
Viral Infections ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Respiratory Viral Infections

scholarly journals Molecular Basis for Treating COVID-19 with Official Chinese Herbal Formula LCTE

2020 ◽  
Author(s):  
Deng-hai Zhang ◽  
Xue Zhang ◽  
Bin Peng ◽  
Sheng-qiong Deng ◽  
Yu-fang Wang ◽  
...  
Keyword(s):  
Molecular Basis ◽  
Lung Diseases ◽  
Chemical Compounds ◽  
Medical Society ◽  
Network Pharmacology ◽  
General Effect ◽  
Herbal Formula ◽  
Biological Mechanisms ◽  
Chinese Herbal Formula ◽  
Chinese Herbal

Abstract Chinese herbal formulas, notably the lung-cleaning and toxicity-excluding (LCTE) soup has played an important role in treating an ongoing and life-threating worldwide pandemic, COVID-19 (caused by SARS-CoV-2). Applying LCTE outside of China may be difficult for medical society to approach due to the unfamiliar rationale behind its application in terms of Traditional Chinese Medicine. To overcome this barrier, we illuminate the chemical and biological mechanisms behind LCTE’s effects, by exploring the chemical compounds contained in LCTE ingredients, the proteins targeted by these compounds as well as undertaking the network pharmacology analysis. The results disclosed that LCTE contains compounds with the potential to directly inhibit SARS-CoV-2 and inflammation, and that the compounds targeted proteins significantly related to the main symptoms seen in COVID-19. The general effect of LCTE was to affect the pathways involved in viral and other microbe infection, inflammation/cytokine response, and lung diseases. Our work provided chemical biological explanations for using LCTE to treat COVID-19.

scholarly journals Components of Goutengsan in Rat Plasma by Microdialysis Sampling and Its Protection on Aβ1–42-Induced PC12 Cells Injury

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Hou-Cai Huang ◽  
Chun-Fei Wang ◽  
Jun-Fei Gu ◽  
Juan Chen ◽  
Xue-Feng Hou ◽  
...  
Keyword(s):  
Protective Effect ◽  
Pc12 Cells ◽  
Rat Plasma ◽  
Herbal Formula ◽  
Microdialysis Sampling ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Effective Components ◽  
Pachymic Acid

Goutengsan, a Chinese herbal formula, potential protection on Alzheimer’s disease (AD) has been less reported. In current study, we investigated the protection of Goutengsan on Aβ1–42-induced pheochromocytoma-derived cells (PC12). Furthermore, the components from Goutengsan in rat plasma were identified by microdialysis (MD) forin vivosampling. Meanwhile, the protection of components identified was also verified. At last, we found that Goutengsan has a potential protective effect on Aβ1–42-induced PC12 cells via reducing cells damage and increasing cells vitality as well as six components (pachymic acid, liquiritin, rhynchophylline, isorhynchophylline, corynoxeine, and isocorynoxeine) which may be effective components. This study helps to understand the treatment of Goutengsan for AD and would facilitate the clinical and further studies for this formula.

scholarly journals Anti-Inflammatory Activities of a Chinese Herbal Formula IBS-20 In Vivo and In Vitro

2011 ◽  
Vol 140 (5) ◽  
pp. S-515
Author(s):  
Zhonghan Yang ◽  
Viktoriya Grinchuk ◽  
Terez Shea-Donohue ◽  
Chun-Tao Che ◽  
Lixing Lao ◽  
...  
Keyword(s):  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Anti Inflammatory

scholarly journals Jiedu Xiaozheng Yin, a Chinese herbal formula, inhibits tumor angiogenesis via downregulation of VEGF-A and VEGFR-2 expression in vivo and in vitro

2012 ◽  
Vol 29 (3) ◽  
pp. 1080-1086 ◽  
Author(s):  
ZHIYUN CAO ◽  
WEI LIN ◽  
ZHENGRONG HUANG ◽  
XUZHENG CHEN ◽  
JINYAN ZHAO ◽  
...  
Keyword(s):  
Tumor Angiogenesis ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal
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