scholarly journals Larvicidal activity of Dregea volubilis and Bombax malabaricum leaf extracts against the filarial vector Culex quinquefasciatus

2011 ◽  
Vol 4 (6) ◽  
pp. 436-441 ◽  
Author(s):  
Emdad Hossain ◽  
Anjali Rawani ◽  
Goutam Chandra ◽  
Subhash C. Mandal ◽  
Jayanta Kumar Gupta
2014 ◽  
Vol 4 ◽  
pp. S373-S377 ◽  
Author(s):  
Murugesan Sakthivadivel ◽  
Palani Gunasekaran ◽  
Jeevanandham Therasa Annapoorani ◽  
David Arul Samraj ◽  
Subramanian Arivoli ◽  
...  

Author(s):  
Rathnasagar K ◽  
Thiyagaraj Anand

Objectives: The activity of two different leaf extracts of Lantana indica and Vitex negundo is tested against the 3rd and 4th instar Culex quinquefasciatus larvae to evaluate the potency of the extracts as a larvicide and to find an ecologically sustainable alternative to chemical insecticides. A bioinformatics screening approach was performed to evaluate the in vivo results.Methods: The obtained larvae’s from nearby water sources were tested with N, N-diethyl-meta-toluamide (DEET) as the positive control which is the commercial chemical mosquito repellent and the solvents used for the respective plant extracts act as the negative control. Petroleum ether (PE), ethyl acetate (EA) and an aqueous (AQ) extract were prepared for both L. indica and V. negundo extracts, and its larvicidal activity was tested. A docking based approach was used to study the inhibitory effect of known active compounds from L. indica and V. negundo against acetylcholine esterase (AChE) and sterol binding protein as targets.Results: On comparing the results between three plants extract for its larvicidal activity, the EA extract of V. negundo and L. indica is found to be potent with a low LC50 value. Further, the docking studies between active compounds of L. indica and V. negundo with AChE and Sterol binding protein as targets showed that the compound tangeritin-1 had a good docking score compared to DEET and could be a natural alternative for larvicidal activity in the mosquito.Conclusion: Individual activity of tangeritin-1 could be further studied with mosquito mortality studies and molecular simulations and develop tangeritin-1 as a potential larvicidal compound for commercial use.


ENTOMON ◽  
2021 ◽  
Vol 46 (2) ◽  
pp. 105-112
Author(s):  
Annie Rubens ◽  
P. Philip Samuel

In the current investigation, different solvent leaf extracts of Nelumbo nucifera were tested for their mosquitocidal potential against the filarial vector Culex quinquefasciatus. Further, bioactive compounds of the crude leaf extracts of N. nucifera were identified using GC-MS analysis. The benzene leaf extracts of N. nucifera showed significant egg, larval and pupal mortality at concentrations of 62.5, 125, 250 and 500 ppm, respectively. Mortality of ovicidal, larvicidal and pupicidal effect at 500 ppm at 48 h period were 89, 38 and 67 per cent with LC50 values 4.247, 6.694 and 4.975 and LC90 values 5.881, 9.628, 6.565 ppm, respectively. GC-MS profile of the leaf showed seven peaks and the major components identified as nuciferine, steporphine and mecambroline (29.40%). The study confirms N. nucifera has significant mosquitocidal effects.


Author(s):  
Funmilayo G. Famuyiwa ◽  
Francis B. Adewoyin ◽  
Oluyemi J. Oladiran ◽  
Oluwatosin R. Obagbemi

Aim: The methanol extracts of fifteen plants and their partitioned fractions were screened for larvicidal activity against the fourth instar of larvae Culex quinquefasciatus, the vector of lymphatic filariasis with a view to identifying the active ones. Methodology: The plant parts were collected, separately dried and milled. Each powdered material was extracted in methanol at room temperature for 3 days, with agitation. The extract was filtered and concentrated in vacuo. Each extract was tested against the fourth instar larvae of Cx. quinquefasciatus. The methanol extracts were suspended in water and successively partitioned into n-hexane and ethylacetate. Each partitioned fraction was also tested against the fourth instar larvae of Cx. quinquefasciatus. Results: About fifty six percent (56.3%) of the tested extracts had moderate larvicidal activity after 48 hours. The fruit extract of Thevetia neriifolia and the leaf extracts of Calotropis procera and Solanum macrocarpon were the most active. After partitioning the methanol extracts, each of the plant extracts had one or two highly active partitioned fractions after 48 hours. The n-hexane fractions of S. macrocarpon (0.78 ± 0.03 mg/mL) and Spondias mombin (0.81 ± 0.03 mg/mL) were the most active. Conclusion: The non-polar fractions of S. macrocarpon and S. mombin were the most active. Purification of these highly active fractions could lead to the isolation of potent larvicidal compounds that could be used in the control of Cx. quinquefasciatus mosquito.


2012 ◽  
Vol 111 (3) ◽  
pp. 1025-1035 ◽  
Author(s):  
Kalimuthu Kovendan ◽  
Subramaniam Arivoli ◽  
Rajan Maheshwaran ◽  
Kathirvelu Baskar ◽  
Savariar Vincent

Author(s):  
POONGUZALI J ◽  
KALAIVANI M

Objective: Mosquitoes are one of the most significant vectors among arthropods. Infection due to mosquito plays a major health problem in developing countries. Repeated use of synthetic insecticides for mosquito control has disrupted natural biological control systems and led to resurgences in mosquito populations. Plants may be an alternative source of mosquito control, potential as insecticide. Controlling of mosquitoes at the larval stage is easy, as target specificity of the larvicide used can be ensured. Methods: The present study has assessed the role of larvicidal activity of aqueous, chloroform, and methanol leaf extracts of Vitex negundo plant against first, second, third, and fourth instar larvae of Culex quinquefasciatus. Mortality rates were recorded after 24 h and 48 h to evaluate the larvicidal activity against C. quinquefasciatus. Results: Among the three extracts, the methanol extract was found to be the most effective providing 86.67% mortality at 200 ppm concentration against the larvae of C. quinquefasciatus, when compared with aqueous and chloroform extracts, where the mortality rate is 83.33% and 70.00%, respectively. Conclusions: The results therefore clearly indicate that V. negundo leaf extracts possess larvicidal activity against the larvae and could be a possible source of mosquito larvicides.


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