The slow rise of the quantum

2011 ◽  
pp. 89-157
Author(s):  
Andrew Whitaker
Keyword(s):  
Slow Rise

Serum insulin response to slow-rise glucose infusion in "genetic prediabetics" (offspring of two diabetic parents)

Diabetes ◽  
1977 ◽  
Vol 26 (5) ◽  
pp. 490-499 ◽  
Author(s):  
M. H. Tan ◽  
R. F. Williams ◽  
J. S. Soeldner ◽  
R. E. Gleason
Keyword(s):  
Serum Insulin ◽  
Insulin Response ◽  
Glucose Infusion ◽  
Slow Rise

The fate and uptake of murine epidermal growth factor in the sheep

1989 ◽  
Vol 123 (1) ◽  
pp. 121-130 ◽  
Author(s):  
L. M. Tyson ◽  
C. A. Browne ◽  
G. Jenkin ◽  
G. D. Thorburn
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Bolus Injection ◽  
Kidney Cortex ◽  
Kidney Medulla ◽  
Body Tissues ◽  
Rapid Fall ◽  
Epidermal Growth ◽  
Slow Rise ◽  
Initial Bolus

ABSTRACT 125I-Labelled murine epidermal growth factor (EGF) was injected or infused into conscious ewes through the jugular vein. Its disappearance from the circulation and the pattern of its distribution in other body tissues and compartments were observed. Single bolus injections of 125I-labelled EGF resulted in a transient peak of radioactive EGF in the circulation which occurred within 1 min of the injection. This was followed by a very rapid fall in radioactivity in the plasma (t½ ∼ 1 min) and the gradual appearance of 125I-labelled EGF in the urine. Immunoprecipitable 125I-labelled EGF could be detected in urine within 5 min of the start of the experiment. 125I-Labelled EGF accumulated in the urine for several hours following the injection, although with increasing time a substantial amount of non-immunoprecipitable iodide was also found. The rate of disappearance of the 125I-labelled EGF from the plasma of the ewe was found to be faster than the rate of disappearance of free [125I]iodide that had been injected into the ewe. 125I-Labelled EGF was also administered by a continuous infusion following an initial bolus injection. This again resulted in a rapid initial fall in radio-activity in blood, followed by a slow rise throughout the period of the infusion. When the infusion was stopped, there was a 15-min period of rapid readjustment, after which the radioactivity in the blood fell at a much slower rate (t½ ∼70 min) than was seen initially. Again, intact 125I-labelled EGF was transferred to urine throughout the experiment. At autopsy, 125I-labelled EGF was increased in bile, liver, thyroid and kidney. Although most of the 125I found in the thyroid was free iodide, some EGF-like material was also present. There was also EGF-like material found in both the kidney cortex and the kidney medulla. These results indicate that complex multi-compartment pathways for the uptake, distribution and clearance of 125I-labelled EGF exist in the sheep. Journal of Endocrinology (1989) 123, 121–130

scholarly journals Situation of PMTCT in Bhutan, 14 Years’ Experience

2020 ◽  
Vol 6 (1) ◽  
pp. 49-54
Author(s):  
Phurb Dorji ◽  
Ripa Chakma ◽  
Lekey Khandu
Keyword(s):  
Scientific Evidence ◽  
Hiv Infections ◽  
Pmtct Program ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Effective Strategies ◽  
First Case ◽  
Mtct Rate ◽  
Slow Rise ◽  
Mother To Child

Introduction: Prevention of mother-to-child transmission activities form important part of HIV/AIDS prevention program of any community or country. Methods: Information from the PMTCT Programme from the Ministry of Health and other published literature on HIV in Bhutan were reviewed. Results: The first case of mother to child transmission was reported in Bhutan in 2001. However, the retrospective study shows that one of the earliest mothers-to- child transmissions could have taken place back in 1997. Strategies for the prevention of mother-to-child transmission (PMTCT) of HIV in Bhutan have endured substantial advancement based on global scientific evidence. It is a concern as there is a slow rise in the number of HIV cases. The main modeof transmission is unsafe heterosexual practice in Bhutan. Before the planned PMTCT program, 3 children were infected. After launch of proper PMTCT program, we had all the components of effective strategies in PMCT program which have evolved with better ones with time. Due to this, MTCT was 3.2%. With undetected HIV infections, 32 children were born outside of the program and actual national MTCT rate is 5.5%. Conclusion: There is increasing number of people every year with new HIV infections. In addition, our detection gap is 45% with about 602 undiagnosed in the community. Every effort should be put forward to upscale the PMTCT program for Bhutan to eliminate Mother-to-Child transmission (MTCT) of HIV by 2020 and beyond.

scholarly journals Crust or core? Insights from the slow rise of large glitches in the Crab pulsar

2018 ◽  
Vol 481 (1) ◽  
pp. L146-L150 ◽  
Author(s):  
B Haskell ◽  
V Khomenko ◽  
M Antonelli ◽  
D Antonopoulou
Keyword(s):  
Crab Pulsar ◽  
Slow Rise

The Mechanical Properties of the Cell Surface

1955 ◽  
Vol 32 (4) ◽  
pp. 734-750 ◽  
Author(s):  
J. M. MITCHISON ◽  
M. M. SWANN
Keyword(s):  
Cell Surface ◽  
Young’S Modulus ◽  
Sea Water ◽  
Young's Modulus ◽  
Contractile Ring ◽  
A Value ◽  
Sudden Rise ◽  
Slow Rise ◽  
Stage Yield ◽  
Sperm Aster

1. Measurements with the cell elastimeter on the stiffness of the cell membrane of fertilized sea-urchin eggs show the following general features. There is a sudden rise at fertilization, followed by a fall during the early sperm aster stage to the lowest value reached during development (a Young's modulus of about 0.58 x 104 dynes/cm.2). The stiffness rises slowly until metaphase, after which it rises rapidly to reach a maximum during late anaphase and early cleavage (6.81 x 104 dynes/cm.2). During the later stages of cleavage the stiffness falls again and reaches a value in the second interphase which is about twice as high as in the first interphase. Masurements on naked eggs in calcium-free sea water indicate that the slow rise in metaphase is due to the development of the hyaline layer. 2. Measurements on swollen and shrunken eggs at cleavage indicate that there is no interal pressure in the eggs at this stage, but similar experiments with eggs at the sperm aster stage yield anomalous results. Observations on the wrinkling point in shrunken eggs show that the maximum possible internal pressure is 19 dynes/cm.2 for sperm aster eggs and 500 dynes/cm.2 for cleaving eggs. 3. The bearing of these results on various theories of the mechanism of cleavage is briefly discussed. The rise in Young's modulus of the whole cell surface at cleavage argues against theories depending on the action of the spindle and asters, and against theories proposing a contractile ring in the surface. The rise is, however, what might be expected on the basis of the expanding membrane theory.

THE USE OF INDIRECT ARTERIAL PULSE TRACINGS IN THE DIAGNOSIS OF CONGENITAL HEART DISEASE

PEDIATRICS ◽  
1956 ◽  
Vol 18 (2) ◽  
pp. 205-213
Author(s):  
Ephraim Donoso ◽  
Samuel O. Sapin ◽  
Leslie A. Kuhn ◽  
Arthur Grishman
Keyword(s):  
Coarctation Of The Aorta ◽  
Subaortic Stenosis ◽  
Arterial Pulse ◽  
Clinical Criteria ◽  
Dicrotic Notch ◽  
Valvular Stenosis ◽  
Slow Rise ◽  
Criteria For Diagnosis ◽  
Carotid Vessels ◽  
Carotid Arterial

Studies were made of the carotid arterial pulse curves, recorded by indirect means utilizing a crystal microphone system, of 21 normal patients and 38 patients fulfilling the clinical criteria of congenital aortic or subaortic stenosis, 6 of whom had coexisting coarctation of the aorta. There were definite and constant abnormalties in the pulse curves of the carotid artery in the group with aortic or subaortic stenosis. These were characterized by the presence of an initial sharp anacrotic notch placed low on the ascending limb of the Pulse curve; a series of systolic vibrations on the ascending limb, the graphic representation of a palpable thrill in the carotid vessels of these patients; plateau formation near the peak of the curve; a slow rise of the ascending limb of the curve to reach a later peak than normally seen; and, in some cases, an increased duration of systole as measured from the beginning of the carotid upstroke to the dicrotic notch of the carotid. Although the patients studied would appear to fulfill the clinical criteria for diagnosis of congenital subaortic stenosis as opposed to congenital aortic valvular stenosis, it is emphasized that the differential diagnosis of these 2 conditions may not be possible during the life of the patient. It is stressed that congenital aortic or subaortic stenosis may be considerably more frequent than can be judged by previously reported necropsy statistics and that, in addition, there may be a frequent association of these conditions with coarctation of the aorta.

scholarly journals Effect of Adhesive Debonding on the Performance of Piezoelectric Sensors in Structural Health Monitoring Systems

Sensors ◽  
2019 ◽  
Vol 19 (23) ◽  
pp. 5070 ◽  
Author(s):  
Liu ◽  
Xu ◽  
Li ◽  
Wang ◽  
Zhang
Keyword(s):  
Structural Health Monitoring ◽  
Health Monitoring ◽  
Research Work ◽  
Piezoelectric Sensor ◽  
Systematic Investigation ◽  
Monitoring Method ◽  
Structural Health ◽  
Negative Effect ◽  
Inherent Frequency ◽  
Slow Rise

Piezoelectric (PZT) ceramic elements are often subjected to complex loads during in- service lifetime in structural health monitoring (SHM) systems, and debonding of both excitation actuators and receiving sensors have a negative effect on the monitoring signals. A first systematic investigation of debonding behaviors by considering actuators and sensors simultaneously was performed in this paper. The debonding areas of actuators were set in different percentage range from 0% to 70%, and sensors in 0%, 20%, 40% and 60%. The signal-based monitoring method was used to extract the characteristic parameters of both the amplitudes and phases of received signals. Experimental results revealed that as the debonding areas of the actuators increase, the normalized amplitude appears a quick decrease before 35% debonding area of actuators and then a slow rise until 60% of debonding reached. This may be explained that the 35% debonding turning point correspond to the coincidence of the excitation frequencies of peripheral actuators with the inherent frequency of the central piezoelectric sensor, and the 60% be the result of the maximum ability of piezoelectric sensor. The degrees of debonding of actuators and sensors also have significant influence on the phase angle offset, with large debonding of actuators increases the phase offset sharply. The research work may provide useful information for practical monitoring of SHM systems.

scholarly journals New Evidence for the Role of Emerging Flux in a Solar Filament’s Slow Rise Preceding Its CME‐producing Fast Eruption

2007 ◽  
Vol 669 (2) ◽  
pp. 1359-1371 ◽  
Author(s):  
Alphonse C. Sterling ◽  
Louise K. Harra ◽  
Ronald L. Moore
Keyword(s):  
Slow Rise ◽  
New Evidence
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