scholarly journals P.193 Competitive Flow Diversion: Proposed Classification System

Author(s):  
MA MacLean ◽  
T Huynh ◽  
M Schmidt ◽  
VM Pereira ◽  
A Weeks

Background: Competitive flow diversion (CFD) is a novel application of flow diversion stenting (FDS), redirecting flow into a normal artery proximal or distal to the aneurysmal parent artery. A classification system for CFD has not been previously reported. Methods: Report of operative technique and novel classification system for CFD. Results: A patient with subarachnoid haemorrhage and three aneurysms arising from the Pcomm-P1 complex, was treated with endovascular coiling and CFD. The PCOM aneurysm was coiled. Two aneurysms arose from the distal right P1- PCA. After a failed attempt to treat with FDS across the P1-PCA, the P1-aneurysms were successfully treated with CFD distal to the P1-PCA, from Pcomm to P2. Over 12 months, CFD redirected flow via ICA-Pcomm-P2, reducing the size of the P1-PCA, obliterating the P1-aneurysms. Herein, we classify competitive flow diversion into two types. Type I CFD is when the parent artery harbouring the aneurysm is “jailed” proximally. Type II CFD occurs when flow is diverted from the parent artery distal to the aneurysm origin. Conclusions: Herein, we propose a novel classification for CFD. We describe the first case of aneurysm occlusion in the circle of Willis with Type II CFD, and use of CFD for the treatment of multiple adjacent aneurysms.

2018 ◽  
Vol 22 (5) ◽  
pp. 532-540 ◽  
Author(s):  
Geoffrey P. Colby ◽  
Bowen Jiang ◽  
Matthew T. Bender ◽  
Narlin B. Beaty ◽  
Erick M. Westbroek ◽  
...  

Intracranial aneurysms in the pediatric population are rare entities. The authors recently treated a 9-month-old infant with a 19-mm recurrent, previously ruptured, and coil-embolized left middle cerebral artery (MCA) pseudoaneurysm, which was treated definitively with single-stage Pipeline-assisted coil embolization. The patient was 5 months old when she underwent resection of a left temporal Grade 1 desmoplastic infantile ganglioglioma at an outside institution, which was complicated by left MCA injury with a resultant 9-mm left M1 pseudoaneurysm. Within a month, the patient had two aneurysmal rupture events and underwent emergency craniectomy for decompression and evacuation of subdural hematoma. The pseudoaneurysm initially underwent coil embolization; however, follow-up MR angiography (MRA) revealed aneurysm recanalization with saccular enlargement to 19 mm. The patient underwent successful flow diversion–assisted coil embolization at 9 months of age. At 7 months after the procedure, follow-up MRA showed complete aneurysm occlusion without evidence of in-stent thrombosis or stenosis. Experience with flow diverters in the pediatric population is still in its early phases, with the youngest reported patient being 22 months old. In this paper the authors report the first case of such a technique in an infant, whom they believe to be the youngest patient to undergo cerebral flow diversion treatment.


2021 ◽  
Author(s):  
Anhong Wang ◽  
Weili Shi ◽  
Linxin Chen ◽  
Xing Xie ◽  
Feng Zhao ◽  
...  

Abstract Background Current classifications emphasize the morphology of the coalition, however, subtalar joint facets involved should also be emphasized.Objective The objective of this study was to develop a new classification system based on the articular facets involved to cover all coalitions and guide operative planning.Methods Patients were diagnosed with talocalcaneal coalition using a CT scan, between January 2009 and February 2021. We classified the coalition into four main types according to the shape and nature of the coalition: I, inferiorly overgrown talus or superiorly overgrown calcaneus; II, both talus and calcaneus overgrew; III, coalition with an accessory ossicle; (I-III types are non-osseous coalition) IV, complete osseous coalition. Then each type was further divided into three subtypes according to the articular facets involved. A, the coalition involving the anterior facets; M, the coalition involving the middle facets, and P, the coalition involving the posterior facets.Results There were 106 patients (108 feet) included in this study. Overall, 8 feet (7.5%) were classified as type I, 75 feet (69.4%) as type II, 7 feet (6.5%) as type III, and 18 feet (16.7%) as type IV. Twenty-nine coalitions (26.9%) involved the posterior facets only (subtype-P), 74 coalitions (68.5%) involved both the middle and posterior facets (subtype-MP), and five coalitions (4.6%) simultaneously involved the anterior, middle, and posterior facets (subtype-AMP). Type II-MP coalition was the most common.Conclusion A new classification system of the talocalcaneal coalition to facilitate operative planning was developed.


2013 ◽  
Vol 35 (4) ◽  
pp. E4 ◽  
Author(s):  
Daniel E. Couture ◽  
John C. Crantford ◽  
Aravind Somasundaram ◽  
Claire Sanger ◽  
Anne E. Argenta ◽  
...  

Object There has been a tremendous increase in the incidence of deformational plagiocephaly in children throughout the world. Therapeutic options include observation, active counterpositioning, external orthotics, and surgery. The current treatment in the US is highly debated, but it typically includes external orthotic helmets in patients with moderate to severe plagiocephaly presenting between 4 and 10 months of age or in children with significant comorbidities limiting passive (no-pressure) therapy. The present study was designed to evaluate 3 key issues: 1) the accuracy of the Argenta classification in defining a progressive degree of severity, 2) identification of an upper age limit when treatment is no longer effective, and 3) the effectiveness of an off-the-shelf prefabricated helmet in correcting deformational plagiocephaly. Methods An institutional review board–approved retrospective study was conducted of all patients at the authors' clinic in whom deformational plagiocephaly was assessed using the Argenta classification system over a 6-year period; the patients underwent helmet therapy, and a minimum of 3 clinic visits were recorded. Inclusion criteria consisted of an Argenta Type II–V plagiocephalic deformity. Patients' conditions were categorized both by severity of the deformity and by patients' age at presentation. Statistical analysis was conducted using survival analysis. Results There were 1050 patients included in the study. Patients with Type III, IV, and V plagiocephaly required progressively longer for deformity correction to be achieved than patients with Type II plagiocephaly (53%, 75%, and 81% longer, respectively [p < 0.0001]). This finding verified that the Argenta stratification indicated a progressive severity of deformity. No statistically significant difference in the time to correction was noted among the different age categories, which suggests that the previously held upper time limit for correction may be inaccurate. An overall correction rate to Type I plagiocephaly of 81.6% was achieved irrespective of severity and degree of the original deformity. This suggests that an inexpensive off-the-shelf molding helmet is highly effective and that expensive custom-fitted orthoses may not be necessary. The patients in the older age group (> 12 months) did not have a statistically significant longer interval to correction than the patients in the youngest age group (< 3 months). The mean length of follow-up was 6.3 months. Conclusions Patients treated with passive helmet therapy in the older age group (> 12 months) had an improvement in skull shape within the same treatment interval as the patients in the younger age group (< 3 months). This study supports the use of passive helmet therapy for improvement in deformational plagiocephaly in infants from birth to 18 months of age and verifies the stratification of degree of deformity used in the Argenta classification system.


2019 ◽  
Vol 12 (2) ◽  
pp. e014475 ◽  
Author(s):  
Shamick Biswas ◽  
Nihar Vijay Kathrani ◽  
Saini Jitender ◽  
Arun Kumar Gupta

We report the first case of a post-traumatic direct carotid cavernous fistula (CCF) treated with the XCalibur aneurysm occlusion device, which is a balloon mounted stent with flow diversion effect. Two devices were deployed across the fistula in an overlapping manner, resulting in complete occlusion of the fistula. Flow diversion with this device can provide a safe and alternative treatment option in direct CCF.


2021 ◽  
Vol 12 ◽  
Author(s):  
Jinlu Yu ◽  
Xianli Lv

Background: Few reports have shown the therapeutic outcomes of flow diversion (FD) for intracranial aneurysms beyond the circle of Willis, and the efficacy of this technique remains unclear.Materials and methods: A retrospective study was performed on 22 consecutive patients, diagnosed with intracranial aneurysms beyond the circle of Willis, and treated with pipeline embolization device (PED) (Medtronic, Irvine, California, USA) between January 2015 and December 2019.Result: The 22 patients were between 16 and 66 years old (mean 44.5 ± 12.7 years), and six patients were male (27.3%, 6/22). Twenty-two patients had 23 aneurysms. The 23 aneurysms were 3–25 mm in diameter (12.2 ± 7.1 mm on average). The diameter of the parent artery was 1.3–3.0 mm (2.0 ± 0.6 mm on average). The 23 aneurysms were located as follows: 17 (73.9%, 17/23) were in the anterior circulation, and 6 (26.1%, 6/23) were in the posterior circulation. PED deployment was technically successful in all cases. Two overlapping PEDs were used to cover the aneurysm neck in 3 cases. One PED was used to overlap the two tandem P1 and P2 aneurysms. Other cases were treated with single PED. Coil assistance was used to treat 7 aneurysms, including 4 recurrent aneurysms and 3 new cases requiring coiling assistance during PED deployment. There were no cases of complications during PED deployment. All patients were available at the follow-up (mean, 10.9 ± 11.4 months). All patients presented with a modified Rankin Score (mRS) of 0. During angiographic follow-up, complete embolization was observed in 22 aneurysms in 21 patients, and one patient had subtotal embolization with the prolongation of stasis in the arterial phase.Conclusion: PED deployment for intracranial aneurysms beyond the circle of Willis is feasible and effective, with high rates of aneurysm occlusion.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Anhong Wang ◽  
Weili Shi ◽  
Lixiang Gao ◽  
Linxin Chen ◽  
Xing Xie ◽  
...  

Abstract Background Current classifications emphasize the morphology of the coalition, however, subtalar joint facets involved should also be emphasized. Objective The objective of this study was to develop a new classification system based on the articular facets involved to cover all coalitions and guide operative planning. Methods Patients were diagnosed with talocalcaneal coalition using a CT scan, between January 2009 and February 2021. The coalition was classified into four main types according to the shape and nature of the coalition: I, inferiorly overgrown talus or superiorly overgrown calcaneus; II, both talus and calcaneus overgrew; III, coalition with an accessory ossicle; IV, complete osseous coalition (I-III types are non-osseous coalition). Then each type was further divided into three subtypes according to the articular facets involved. A, the coalition involving the anterior facets; M, the coalition involving the middle facets, and P, the coalition involving the posterior facets. Interobserver reliability was measured at the main type (based on nature and shape) and subtype (articular facet involved) using weighted Kappa. Results There were 106 patients (108 ft) included in this study. Overall, 8 ft (7.5%) were classified as type I, 75 ft (69.4%) as type II, 7 ft (6.5%) as type III, and 18 ft (16.7%) as type IV. Twenty-nine coalitions (26.9%) involved the posterior facets only (subtype-P), 74 coalitions (68.5%) involved both the middle and posterior facets (subtype-MP), and five coalitions (4.6%) simultaneously involved the anterior, middle, and posterior facets (subtype-AMP). Type II-MP coalition was the most common. The value of weighted Kappa for the main type was 0.93 (95%CI 0.86–0.99) (p<0.001), and the value for the subtype was 0.78 (95%CI 0.66–0.91) (p<0.001). Conclusion A new classification system of the talocalcaneal coalition to facilitate operative planning was developed.


1918 ◽  
Vol 17 (2-3) ◽  
pp. 350-365 ◽  
Author(s):  
J. A. Glover

(1) There were nineteen cases and eight deaths at the depot during the epidemic.One doubtful case during this period recovered, and a sporadic case in June due to Type I also recovered; these are not included in the above, nor is one man who went on leave to Blackpool, and developed the disease (Type II) on arrival.(2) So far the reserve battalions have had three cases only, with two deaths, although a high carrier-rate wave has been detected in two.(3) All the cases (except the June case) at the depot occurred during exceptionally cold weather. In the chart the cases appear to lie in thetrough of a great depression of the curve of mean weekly temperature (broken line). They also follow immediately upon exceptional crowding (black line).(4) There was a well-marked premonitory rise in the carrier-rate in December 1916, before the first case occurred, and an enormous rise before the epidemic was really established.The carrier-rate, which was 19·25% on December 23rd, reache dwhat is usually considered the danger point of 20% (see War OfficeMemorandum on Cerebro-spinal Fever, page 2) just six days before the first case occurred.It would appear that estimations of the carrier-rate by means of large sample swabbings afford a reliable warning of the imminence or danger of an epidemic.(5) The cases in the epidemic were nearly all due to the meningococcus of Type II, the organism present in the outbreak of 1916.The rise in the carrier-rate was also chiefly due to the increase ofcarriers of this type. Freshly joined recruits showed few carriers at all and very few Type II carriers when swabbed before having slept in the barracks.(6) During the epidemic, the carrier-rate among non-contacts was substantially the same as amongst the actual contacts of cases, averaging34% for the period, in each case.(7) The proportion of agglutinable strains to inagglutinable strains of organisms morphologically indistinguishable from the meningococcus increased very markedly during the epidemic period.(8) The treatment of the whole population by the steam zinc sulphate solution spray (which was carried out daily for two seven-day periods with an interval of a fortnight), was followed by a satisfactory drop in the carrier-rate, and by a temporary cessation of cases on each occasion.(9) 60% of the actual patients suffering from the disease were in their first month of service.40% of the patients had either been inoculated or vaccinated within seven days of onset (three on the same day); 60% within afortnight.(10) Previous and concurrent epidemics of German measles, influenza and bronchitis had helped (by causing coughing and sneezing and by lowering vitality) to produce the great rise in the carrier-rate, which culminated in the case epidemic.


2021 ◽  
Vol 11 ◽  
Author(s):  
Lingxi Nan ◽  
Changcheng Wang ◽  
Yajie Dai ◽  
Jie Wang ◽  
Xiaobo Bo ◽  
...  

BackgroundCystic duct carcinoma (CDC) is a rare biliary malignancy with a low incidence and poor prognosis. However, the clinical landscape of the disease has not been clarified and no widely applicable classification system has been developed.MethodsSixty-two patients with CDC were included in this retrospective study, and a new classification system was established using imaging data. Blood indices, radiological characteristics, pathological features, surgical procedures, and overall survival data were collected. The efficacy of the new classification in predicting resectability was evaluated using receiver operating characteristic (ROC) curves, and K-means clustering and t-distributed stochastic neighbor embedding were applied to verify the conclusion.ResultsThe pT stage of patients with type II CDC was significantly worse than that of type I. Patients with type II CDC were more likely to experience distant metastasis and invasion of the nervous system, vascular system, and liver. The resectability of patients with type II CDC was significantly worse than that of patients with type I CDC. Patients with type II CDC had worse prognoses. ROC curve analysis and K-means clustering revealed that the new classification could better categorize patients with CDC than currently available systems.ConclusionPatients with type II CDC have significantly worse clinicopathological outcomes. The new classification system has better accuracy in grouping patients with CDC.


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