The less depressive state of Denmark following the second wave of the COVID-19 pandemic

In order to model within-person (WP) variance in a reaction time task, we applied a mixed location scale model using 335 participants from the second wave of the Zurich Longitudinal Study on Cognitive Aging. The age of the respondents and the performance in another reaction time task were used to explain individual differences in the WP variance. To account for larger variances due to slower reaction times, we also used the average of the predicted individual reaction time (RT) as a predictor for the WP variability. Here, the WP variability was a function of the mean. At the same time, older participants were more variable and those with better performance in another RT task were more consistent in their responses.

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Systemic Effects of ADP-induced Platelet Aggregation and Their Modification by Aspirin and by Pyridinolcarbamate

Thrombosis and Haemostasis ◽

10.1055/s-0038-1649115 ◽

1973 ◽

Vol 30 (01) ◽

pp. 178-190 ◽

Cited By ~ 6

Author(s):

Itsuro Kobayashi ◽

Paul Didisheim

Keyword(s):

Platelet Aggregation ◽

Venous Pressure ◽

Systemic Effects ◽

Central Venous ◽

Platelet Aggregates ◽

Induced Changes ◽

Second Wave ◽

Carotid Arterial ◽

Arterial Po2

SummaryADP, AMP, or ATP was injected rapidly intravenously in rats. ADP injection resulted in the f olio wing transient changes: a drop in platelet count, a rise in central venous pressure, a fall in carotid arterial PO2, bradycardia, arrhythmia, flutter-fibrillation, and arterial hypotension. AMP and ATP produced some of these same effects; but except for hypotension, their frequency and severity Avere much less than those following ADP.Prior intravenous administration of acetylsalicylic acid or pyridinolcarbamate, two inhibitors of the second wave of ADP-induced platelet aggregation in vitro, significantly reduced the frequency and severity of all the above ADP-induced changes except hypotension. These observations suggest that many of the changes (except hypotension) observed to follow ADP injection are produced by platelet aggregates which lodge transiently in various microcirculatory beds then rapidly disaggregate and recirculate.

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Two Years after the Crisis: Do Risks of the Second Wave Become Stronger?

Voprosy Ekonomiki ◽

10.32609/0042-8736-2011-12-4-20 ◽

2011 ◽

pp. 4-20

Author(s):

M. Ershov

Keyword(s):

High Risk ◽

World Economy ◽

External Shocks ◽

Global Imbalances ◽

Russian Economy ◽

The World ◽

The Future ◽

Second Wave

With signs of normalization seemingly in place in the world economy, a number of problems show the possibility of aggravation in the future. The volume of derivatives in American banks grows significantly, high risk instruments are back in place and their use becomes more active, global imbalances increase. All of the above requires thorough approaches when creating mechanisms which can neutralize external shocks for the Russian economy and make it possible to develop in the new post-crisis environment.

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Third Wave Feminist Analysis of a Second Wave Feminist's Art

Departures in Critical Qualitative Research ◽

10.1525/dcqr.2015.4.1.57 ◽

2015 ◽

Vol 4 (1) ◽

pp. 57-80 ◽

Cited By ~ 2

Author(s):

Jennifer A. Zenovich ◽

Shane T. Moreman

Keyword(s):

Oral History ◽

Symbolic Order ◽

Oral Histories ◽

Third Wave ◽

Feminist Art ◽

Feminist Analysis ◽

Second Wave

A third wave feminist approach to feminist oral history, this research essay blends both the visual and the oral as text. We critique a feminist artist's art along with her words so that her representation can be seen and heard. Focusing on three art pieces, we analyze the artist's body to conceptualize agentic ways to understand the meanings of feminist art and feminist oral history. We offer a third wave feminist approach to feminist oral history as method so that feminists can consider adaptive means for recording oral histories and challenging dominant symbolic order.

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The Personal is the Political

International Review of Qualitative Research ◽

10.1525/irqr.2010.3.1.125 ◽

2010 ◽

Vol 3 (1) ◽

pp. 125-148

Author(s):

Mercilee M. Jenkins

Keyword(s):

San Francisco ◽

Women's Movement ◽

Community Member ◽

The Political ◽

Oral Histories ◽

Grass Roots ◽

Feminist Organization ◽

Second Wave

This paper explores the transformation of oral histories into a play about the founding of San Francisco Women's Building based on extensive interviews. My impetus for writing She Rises Like a Building to the Sky was to portray the kind of grass roots feminist organization primarily composed of lesbians that made up a large part of the second wave of the Women's Movement in the 1970's and early 1980's. The evolution of She Rises is discussed from three positionalities I occupied over an extensive period of time: oral historian, playwright and eventual community member. Excerpts from She Rises are used to illustrate the lessons I learned in the process of creating this work. I will discuss my self-collaboration in terms of the oral historian's concern for fidelity, the playwright's desire to bring such material to life whether by fact or fiction, and the community member's fears of how others will view this rendition of their stories. The behind the scenes dramas reveal as much as the play itself about the challenges and rewards of undertaking such projects.

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Experimental anxiety-depressive state in rats caused by neonatal exposure to the inhibitor of dipeptidyl peptidase IV, diprotin A: effects of imipramine

ZHurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia» ◽

10.25557/igpp.2017.4.8517 ◽

2017 ◽

pp. 4-12

Author(s):

Н.Н. Хлебникова ◽

Н.А. Крупина

Keyword(s):

Forced Swimming Test ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase Iv ◽

Forced Swimming ◽

Face Validity ◽

Neonatal Exposure ◽

Depressive State ◽

Serum Corticosterone ◽

Old Rats ◽

Swimming Test

В наших предыдущих исследованиях было показано, что ингибитор пролинспецифической пептидазы дипептидилпептидазы-IV (ДП-IV, EC 3.4.14.5) трипептид дипротин А, введенный крысам в 5-18 постнатальные дни, приводит к развитию у крыс подросткового возраста и взрослых животных эмоционально-мотивационных расстройств. Такие расстройства можно рассматривать как модель смешанного тревожно-депрессивного состояния. Однако специальных исследований по валидности данной модели проведено не было. Цель настоящей работы состояла в проверке влияния трициклического антидепрессанта имипрамина (ИМИ) на депрессивноподобное поведение крыс и уровень кортикостерона в сыворотке крови животных на модели смешанного тревожно-депрессивного состояния. Методика. У крыс в возрасте одного и двух мес. определяли уровень тревожности в автоматизированном тесте «Приподнятый крестообразный лабиринт» и оценивали депрессивноподобное поведение в тесте принудительного плавания. ИМИ вводили взрослым животным в течение 10 дней (20 мг/кг/день, интрагастрально). Уровень кортикостерона в сыворотке крови определяли методом твердофазного иммуноферментного анализа. Результаты. Неонатальное действие дипротина А приводило к повышению тревожности у крыс в возрасте 1 мес. Депрессивноподобное поведение обнаружено у животных в возрасте одного и двух мес. ИМИ нормализовал поведение животных в тесте принудительного плавания и снижал уровень кортикостерона в сыворотке крови крыс. Кроме того, ИМИ снижал вес крыс. Заключение. Результаты исследования свидетельствуют в пользу адекватности модели смешанного тревожно-депрессивного расстройства, возникающего у крыс вследствие действия ингибитора ДП-IV дипротина А на второй-третьей неделях постнатального развития, клиническому прообразу заболевания по критериям «внешней схожести», прогностической и конструкционной валидности. Previously, we have shown that the inhibitor of proline-specific peptidase, dipeptidyl peptidase-IV (DP-IV, EC 3.4.14.5), tripeptide diproptin A administered on postnatal days 5-18 induced emotional and motivational disorders in adolescent and adult rats. These disorders can be considered a model of a mixed anxiety-depression-like disorder. However, validation studies of this model are not available. The aim of this work was to test the effect of the tricyclic antidepressant, imipramine (IMI), on depressive-like behavior in rats and the level of serum corticosterone using the model of mixed anxiety-depressive state. Methods. The level of anxiety was assessed by the automated Elevated Plus Maze test and the depressive-like behavior was evaluated by the forced swimming test in one- and two-month old rats. IMI was administered to adult animals for ten days (20 mg/kg a day, intragastrically). Serum corticosterone concentrations were measured using ELISA. Results. The neonatal exposure to diprotin A increased anxiety in one-month old rats. The depressive-like behavior was observed in animals aged one and two months. IMI normalized behavior of animals in the forced swimming test and reduced serum levels of corticosterone. Also, IMI reduced body weight of rats. Conclusion. The results of the study evidenced adequacy of the model of mixed anxiety-depressive state induced by the DP-IV inhibitor, diprotin A, on the second and third postnatal weeks to the clinical prototype of disease according to criteria of face validity, predictive and construct validity.

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