Unusual leiomyoma of the nose (leiomyoblastoma): Report of a case

1981 ◽  
Vol 95 (12) ◽  
pp. 1281-1286 ◽  
Author(s):  
A. Papavasiliou ◽  
L. Michaels

AbstractLeiomyomas or benign tumours of smooth muscle origin are extremely rare in the nose, due to the paucity of significant masses of smooth muscle in this region. A review of the literature revealed only six cases of leiomyoma (Fu and Perzin, 1975; Kambayashi, 1978; MacCaffrey et al., 1978; Maesaka et al., 1966; Kotaka and Furuya, 1973) previously reported and no case of nasal leiomyoblastoma. This variety of benign smooth muscle tumour has been mostly described in the gastrointestinal tract and uterus (Stout, 1962). In this paper we report a case of an unusual nasal leiomyoma arising from the middle turbinate. We believe it is the first in the literature.

1988 ◽  
Vol 102 (12) ◽  
pp. 1159-1160 ◽  
Author(s):  
G. S. Hanna ◽  
A. B. Akosa ◽  
M. H. Ali

AbstractLeiomyoma of the nose and paranasal sinuses is rare. It constitutes about 1 per cent of all benign tumours. This is due to the paucity of smooth muscle in the nose.In this paper, the authors present one case of vascular leiomyoma which arose in the inferior turbinate in a 64-year-old lady. It was treated by partial turbinectomy with the relief of her symptoms of nasal obstruction, epistaxis and facial pain.The English literature on the topic is reviewed.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Efraín Alvarez ◽  
María P. Laberry ◽  
Carlos M. Ardila

Oral leiomyoma is a benign smooth muscle tumor that occurs most frequently in the uterine myometrium, gastrointestinal tract, and skin. Incidence in the oral cavity is considered uncommon. Most cases are reported in adults, with very few cases described in children. A rare case of multiple leiomyomas localized on the tongue, cheek, and floor of the mouth of an 8-month-old baby is reported. The diagnosis of leiomyoma in the oral cavity is mainly determined by histological studies; however, immunohistochemical tests are recommended in order to differentiate from other tumors. Surgical excision of the lesion appears to be the best treatment option. A review of the literature did not reveal any previously reported case of multiple oral leiomyomas.


2015 ◽  
Vol 24 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Jan Ulrych ◽  
Vladimir Fryba ◽  
Helena Skalova ◽  
Zdenek Krska ◽  
Tomas Krechler ◽  
...  

Heterotopic pancreas is a congenital pathology of the gastrointestinal tract, particularly rare in the esophagus. Both symptomatology and findings during preoperative examinations are non-specific and therefore do not often lead to an accurate diagnosis, which is usually revealed only by histopathological assessment of a resected specimen. We report an unusual case of a patient suffering from severe dysphagia caused by heterotopic pancreas in the distal esophagus with chronic inflammation and foci of premalignant changes. This article also reviews 14 adult cases of heterotopic pancreas in the esophagus previously reported in the literature, with the aim of determining the clinical features of this disease and possible complications including rare premalignant lesions and malignant transformation. Especially with regard to those complications, we suggest that both symptomatic and incidentally found asymptomatic lesions should be resected.


2011 ◽  
Vol 64 (6) ◽  
pp. 485-489 ◽  
Author(s):  
Clinton Boyd ◽  
W Glenn McCluggage

BackgroundUterine leiomyomas are extremely common in surgical pathology practice and in the vast majority there are no issues in diagnosis. Progestogens are widely prescribed drugs for a variety of indications, including abnormal uterine bleeding, and are often given to women with leiomyomas but the pathological features of leiomyomas treated with progestogens are poorly described.MethodsWe report the pathological features in eight cases of uterine leiomyomas in women who had been treated with oral progestogens or a progestogen-containing intrauterine device; all cases were received in consultation because the features raised concern for leiomyosarcoma, smooth muscle tumour of uncertain malignant potential or a benign leiomyoma with unusual features. Additionally, we reviewed a series of cases of uterine leiomyomas (n=99) in women who exhibited progestogenic effects in the endometrium.ResultsThe morphological features in the consult cases, which were widespread and marked and which varied somewhat from case to case, included small and/or large areas of infarct-type necrosis (sometimes mimicking coagulative tumour cell necrosis) with surrounding increased cellularity, mitotic activity, nuclear pyknosis, cytoplasmic eosinophilia, epithelioid morphology, stromal oedema, haemorrhage, and myxoid change and infiltration by CD56 positive granulated lymphocytes. Sometimes the features resulted in an almost deciduoid appearance. Similar features were present to a minor degree in significant numbers of the additional series of cases.ConclusionsPathologists should be aware of these progestogen-associated features when reporting uterine leiomyomas whether or not the clinician has indicated that the woman is taking progestogens since otherwise a diagnosis of leiomyosarcoma or smooth muscle tumour of uncertain malignant potential may be rendered. Useful features in suggesting a benign leiomyoma, in addition to recognition of the morphological features described which, in combination, are characteristic of progestogens, are the lack of true nuclear atypia and the low mitotic activity away from the abnormal areas.


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