Leprosy of the larynx

1992 ◽  
Vol 106 (6) ◽  
pp. 518-520 ◽  
Author(s):  
N. K. Soni
Keyword(s):  
Clinical Manifestation ◽  
Lepromatous Leprosy ◽  
Laryngeal Pathology ◽  
Laryngeal Lesions ◽  
Leprosy Patients ◽  
Screening Survey ◽  
Laryngeal Involvement

AbstractThe result of a study conducted on 30 patients of lepromatous leprosy regarding laryngeal involvement is presented. The incidence of leprous laryngitis is 36.6 per cent in this part of India in lepromatous leprosy patients. Leprosy is long standing disease so laryngeal lesions developed gradually and may be asymptomatic in some cases while others have been found to have variety of clinical manifestation in form of congestion, infiltration, nodulation, thickening and fibrosis. Anti-leprosy chemotherapy is equally effective on these lesions. A screening survey of laryngeal pathology in such cases should be done periodically.

Unusual non-trophic ulcerations in leprosy: A case series of 17 patients

2021 ◽  
pp. 004947552199849
Author(s):  
Prakriti Shukla ◽  
Kiran Preet Malhotra ◽  
Parul Verma ◽  
Swastika Suvirya ◽  
Abir Saraswat ◽  
...  
Keyword(s):  
Erythema Nodosum ◽  
Case Series ◽  
Lepromatous Leprosy ◽  
Sweet Syndrome ◽  
Erythema Nodosum Leprosum ◽  
Leprosy Patients ◽  
Atypical Presentations ◽  
Neuropathic Ulcers

Non-neuropathic ulcers in leprosy patients are infrequently seen, and atypical presentations are prone to misdiagnosis. We evaluated diagnosed cases of leprosy between January 2017 and January 2020 for the presence of cutaneous ulceration, Ridley–Jopling subtype of leprosy, reactions and histologic features of these ulcerations. Treatment was given as WHO recommended multi-bacillary multi-drug therapy. We found 17/386 leprosy patients with non-neuropathic ulcers. We describe three causes – spontaneous cutaneous ulceration in lepromatous leprosy (one nodular and one diffuse), lepra reactions (five patients with type 1; nine with type 2, further categorised into ulcerated Sweet syndrome-like who also had pseudoepitheliomatous hyperplasia, pustulo-necrotic and necrotic erythema nodosum leprosum) and Lucio phenomenon (one patient). Our series draws attention towards the different faces of non-neuropathic ulcers in leprosy, including some atypical and novel presentations.

HLA-DQ molecules and the control ofMycobacterium leprae-specific T cell nonresponsiveness in lepromatous leprosy patients

1990 ◽  
Vol 20 (10) ◽  
pp. 2347-2350 ◽  
Author(s):  
Tom H. M. Ottenhoff ◽  
Charlotte Walford ◽  
Yasuharu Nishimura ◽  
N. B. B. Reddy ◽  
Takehiko Sasazuki
Keyword(s):  
T Cell ◽  
Lepromatous Leprosy ◽  
Hla Dq ◽  
Leprosy Patients

scholarly journals Laryngeal involvement causing dysphonia in a 29 year old nursing mother with lepromatous leprosy

2015 ◽  
Vol 21 ◽  
Author(s):  
Sombo Fwoloshi ◽  
Sharon Musonda Machona ◽  
Victor Mudenda ◽  
Owen Ngalamik
Keyword(s):  
Lepromatous Leprosy ◽  
Nursing Mother ◽  
Laryngeal Involvement

scholarly journals Is laryngeal involvement in pemphigus vulgaris rare? A review

2015 ◽  
Vol 1 (1) ◽  
pp. 3
Author(s):  
Mohan Bansal
Keyword(s):  
Case Reports ◽  
Pemphigus Vulgaris ◽  
Google Scholar ◽  
Cochrane Library ◽  
Laryngeal Lesions ◽  
Life Threatening ◽  
Laryngeal Involvement

<p>The lesions of pemphigus in the larynx have been reported as case reports. However, the frequency with which it occurs is not known. The purpose of this study was to investigate the incidence of laryngeal involvement in pemphigus vulgaris and to examine the laryngeal lesions and the treatment in detail. The databases searched were PubMed, EMBASE, Cochrane Library and Google scholar. The involvement of larynx in patients with pemphigus vulgaris is common. The most common parts involved are epiglottis and arytenoids. This study indicates that laryngeal symptoms are common in pemphigus vulgaris. Laryngeal findings must be considered at the beginning of diagnosis for the better management and to prevent life threatening complications.</p>

scholarly journals Clinical variables associated with disability in leprosy cases in northeast Brazil

2015 ◽  
Vol 9 (03) ◽  
pp. 232-238 ◽  
Author(s):  
Victor Santana Santos ◽  
Andressa Mayara Santos de Matos ◽  
Lorena Sheila Alves de Oliveira ◽  
Ligia Mara Dolce de Lemos ◽  
Ricardo Queiroz Gurgel ◽  
...  
Keyword(s):  
Physical Disability ◽  
Lepromatous Leprosy ◽  
Northeast Brazil ◽  
Chi Square ◽  
Factors Associated ◽  
Operational Classification ◽  
Leprosy Patients ◽  
Chi Square Test ◽  
Multibacillary Leprosy ◽  
Significant Factors

Introduction: The clinical outcomes of leprosy include complications such as physical disabilities and deformities that vary according to the degree of impairment of nerve trunks. Knowledge of the factors that lead to the development of these complications is important for disability prevention programs. This study aimed to evaluate clinical factors associated with the occurrence of physical disability in leprosy cases. Methodology: This was a retrospective study of 2,358 cases of leprosy in Aracaju, northeast Brazil, between 2001 and 2011. Analysis was done using the Chi-square test and logistic regression model. Results: Significant factors associated with disability were found to be male gender, having more than two affected nerves, multibacillary leprosy classification, leprosy reaction, and lepromatous leprosy. The multivariate analysis revealed that the associated factors included having more than two affected nerves, leprosy reaction (adjusted odds ratio [aOR]: 2.02, 95% confidence interval [CI]: 1.36 to 3.01), the multibacillary form (aOR: 2.74, 95% CI: 1.84 to 4.08), and lepromatous leprosy (aOR: 4.87, 95% CI: 2.86 to 16.08). Conclusions: The number of affected nerves, leprosy reaction, operational classification, and clinical presentation were identified as the main factors associated with the development of disability in leprosy patients.

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