Extramedullary plasmacytoma of the larynx

1993 ◽  
Vol 107 (11) ◽  
pp. 1049-1051 ◽  
Author(s):  
Izumi Mochimatsu ◽  
Mamoru Tsukuda ◽  
Shuji Sawaki ◽  
Yukio Nakatani

AbstractA case of IgD myeloma in a 54-year-old male with a long-standing history of extramedullary plasmacytoma involving the larynx is reported.The patient was treated with radiation therapy and laryngectomy. Twelve years later, he complained of nasal bleeding. On examination he was found to have large masses in the left nasal cavity and in the left supraclavicular region. Histological examination of both lesions showed plasmacytoma. Serum immunoglobulin studies revealed an IgD monoclonal spike of the lambda type. Bence-Jones protein was present. Using the immunoperoxidase staining technique, cytoplasmic monoclonal IgD was detected.

2020 ◽  
Vol 89 (5) ◽  
pp. 269-272
Author(s):  
R. Jacobs ◽  
B. Van Goethem ◽  
E. Stock ◽  
H. De Cock ◽  
T. Bosmans ◽  
...  

A six-year-old, male, castrated European shorthair cat was presented due to a lifelong history of sneezing, nasal discharge, open-mouth breathing, stertor and vestibular problems. Clinical examination showed absence of airflow through the nostrils. Computed tomography of the head revealed an infiltrative soft tissue attenuating mass in the left nasal cavity, nasopharynx and the left frontal sinus. All of these locations could be successfully accessed through ventral rhinotomy and the mass was completely removed. Histological examination identified it as an inflammatory polyp. All respiratory and neurological symptoms disappeared, and two-and-a-half years after surgery, the cat was still without complaints.


2005 ◽  
Vol 84 (11) ◽  
pp. 720-722 ◽  
Author(s):  
Byoung J. Baek ◽  
Seong W. Kim ◽  
Hoon Park ◽  
Jin K. Park ◽  
Kyung Y. Han ◽  
...  

We report a rare case of extramedullary plasmacytoma of the nasal septum in a 65-year-old woman. She presented with a 2-month history of left-sided nasal obstruction and intermittent blood-tinged nasal crusting. Nasal endoscopy revealed that a dark-red mass had arisen from the nasal septum; no evidence of invasion to adjacent tissues was seen. A biopsy specimen was diagnosed as a plasmacytoma (kappa light chain—type). Serum and urine electrophoresis failed to detect any myeloma component or Bence Jones protein. All other screening tests to rule out multiple myeloma were negative. These findings confirmed the diagnosis of extramedullary plasmacytoma. The mass was completely removed via an endoscopic approach. No recurrence was noted at the 2-year follow-up.


2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Kazuya Takeda ◽  
Yukinori Takenaka ◽  
Michiko Hashimoto

The nasal cavity harbors an enormous variety of neoplasms, including epithelial and mesenchymal tumors. Hemangioma is an infrequent mesenchymal tumor of the nasal cavity, mostly arising in the mucosa and rarely in the bones. We describe the case of a 73-year-old woman who was referred to our hospital with a tumor in her left nasal cavity. The tumor originated from the left inferior turbinate. Histological examination subsequent to complete excision revealed that the tumor was an intraosseous cavernous hemangioma. To our knowledge, this is the second case of intraosseous hemangioma of the inferior turbinate reported in the English literature.


2005 ◽  
Vol 132 (6) ◽  
pp. 963-964 ◽  
Author(s):  
Kaoru Shinohara ◽  
Kimio Hashimoto ◽  
Masaru Yamashita ◽  
Koichi Omori

A 50-year-old woman presented with a 30-year history of nasal obstruction. She had been treated for paranasal sinusitis at other hospitals and she was referred to our hospital for further examination. Flexible endoscopy revealed a mass in the posterior aspect of the right nasal cavity to the posterior aspect of the left nasal cavity around the posterior edge of the nasal septum.


Author(s):  
Mahesh Santhraya G. ◽  
Devan Poothatta Pannen ◽  
Kishor Kumar M. S.

<p class="abstract">Angiosarcoma of the nasal cavity is extremely uncommon accounting for less than 0.1% of all sinonasal malignancies. Here we report a case of angiosarcoma of nasal cavity. A 45 year old male patient with c/o right sided nasal bleeding since 20days, on examination showed mass in nasal cavity. Patient underwent septoplasty with right inferior turbinectomy with submucosal diathermy. The histological examination showed features of angiosarcoma epitheloid variation of nasal cavity, diagnosis was confirmed by immunohistological stain with factor CD 31 and cytokeratin.</p>


2004 ◽  
Vol 128 (1) ◽  
pp. e1-e4 ◽  
Author(s):  
Suman S. Chauhan ◽  
Jayshree Krishnan ◽  
Denis K. Heffner

Abstract We report a solitary fibrous tumor in the nasal cavity of a 48-year-old woman who presented with a history of bilateral nasal obstruction and long-standing cocaine inhalation. Physical examination revealed a large mass involving the right nasal cavity and extending into the posterior aspect of the left nasal cavity. The computed tomography scan showed opacification of airways. During surgery, the mass was found to involve the entire nasal cavity, with extension to the right maxillary sinus, posterior nasal airways, and left nasal cavity. The mass was completely excised. Pathologic examination revealed a polypoid mass 3.7 × 3.0 × 1.2 cm. This tumor was composed of spindle cells that were cytologically bland in a background of ropey and nodular collagen, giving a “patternless” pattern. Immunohistochemically, the neoplastic cells stained for CD34 and vimentin but not for S100 protein, keratin, desmin, HMB-45, and c-Kit. This immunohistochemical pattern confirmed the diagnosis of solitary fibrous tumor. Although solitary fibrous tumors are usually found in the pleura, they can occur in various other locations, such as the orbit, nasal cavity, paranasal sinuses, mediastinum, breast, vagina, meninges, and soft tissues. This case is of interest because the tumor occurred in a patient with prolonged cocaine inhalation. Such an association has not been previously described. The exact causal relationship between cocaine inhalation and the tumor is not known.


1992 ◽  
Vol 106 (4) ◽  
pp. 370-371 ◽  
Author(s):  
S. K. Wan ◽  
J. K. C. Chan ◽  
K. C. Tse

AbstractBasaloid-squamous carcinoma is a recently characterized, aggressive tumour occurring in the hypopharynx, larynx and base of tongue. We report a unique case involving the nasal cavity of a patient with a history of radiation therapy for nasopharyngeal carcinoma, raising the possibilit that basaloid-squamous carcinoma can be radiation-associated.


2016 ◽  
Vol 2016 ◽  
pp. 1-3
Author(s):  
Eugene Wong ◽  
Justin Kong ◽  
Lawrence Oh ◽  
Daniel Cox ◽  
Martin Forer

A unilateral tumour in the nasal cavity or paranasal sinuses is commonly caused by polyps, cysts, and mucoceles, as well as invasive tumours such as papillomas and squamous cell carcinomas. Schwannomas, in contrast, are rare lesions in this area (Minhas et al., 2013). We present a case of a 52-year-old female who presented with a 4-year progressive history of mucous hypersecretion, nasal obstruction, pain, and fullness. Imaging of the paranasal sinuses showed complete opacification of the entire left nasal cavity and sinuses by a tumour causing subsequent obstruction of the frontal and maxillary sinuses. The tumour was completely excised endoscopically. Histopathology was consistent with that of a schwannoma.


2018 ◽  
Vol 8 (32) ◽  
pp. 233-234
Author(s):  
Paskaramoorthy Sasitharan ◽  
Nor Idayu Mohd Yusof ◽  
Kugan Varatha Raju

Abstract Extramedullary plasmacytoma is a rare neoplasm characterized by monoclonal proliferation of plasma cells. It is most often located in the head and neck region. Extramedullary Plasmacytomas are more predominant in males who are in the 5th – 6th decade. In this report, this patient, who is a young female, presented to our clinic with history of intermittent nasal obstruction for the past year. She was diagnosed with extramedullary plasmacytoma and was subjected to radiotherapy. The clinical and histopathologic findings of plasmacytoma are discussed. In order to exclude systemic involvement, a systematic approach using clinical, laboratory and radiologic investigations was performed. Extramedullary plasmacytoma of the nasal cavity is rare and should be considered in the differential diagnosis of nasal cavity masses, especially in the young age group.


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