Rosai—Dorfman disease of the paranasal sinuses

1994 ◽  
Vol 108 (2) ◽  
pp. 152-155 ◽  
Author(s):  
R. T. Gregor ◽  
D. Ninnin

AbstractA 57-year-old man presented with a history of nasal obstruction of five to six years duration. 'Nasal polyps' were removed on several occasions. He had previously had an episode of paraplegia which resolved after the removal of a spinal tumour. Histology from both sites was thought to represent a malignant fibrous histiocytoma. On presentation the patient had computed tomographical (CT) evidence of extensive ethmoidal disease, with threatened intracranial extension. He also had evidence of lung and retroperitoneal disease with pancreas and kidney involvement. The ethmoidal disease was considered potentially lethal and therefore a craniofacial resection was performed. Review of all the histology revealed that the diagnosis was extranodal Rosai–Dorfman disease (sinus histiocytosis). The patient's course is described, and the literature on this disease of unknown aetiology is reviewed.

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Dhara Vaidya ◽  
Parul Shah

Invasive mycotic infections can be effectively treated if rapid identification of fungus is obtained. We reported a case of coinfection byAspergillusandRhizopussp. involving nose, paranasal sinuses, orbit, and brain in a 68-year-old known hypertensive male. He was presented to ENT OPD with history of fever and intermittent headache since fifteen days along with history of right-sided nasal obstruction and proptosis since seven days. CT scan of brain and paranasal sinuses showed findings of pansinusitis with cellulitic changes in right orbit. MRI confirmed the same along with features of intracranial extension with focal meningitis in right frontotemporal region. Laboratory parameters did not conclude much except for leucocytosis and hyponatremia. Patient was taken for endoscopic debridement from nose and paranasal sinuses, and tissue was sent for microbiological and histopathological examination. Minced tissue was processed, and after 48 hrs of incubation two types of growth were identified, one was yellowish, granular, and powdery consistent withAspergillussp., and another was cottony and woolly consistent withRhizopussp. LCB mount confirmed presence ofAspergillus flavusandRhizopus arrhizus. Patient responded to therapy with IV amphotericin B and surgical debridement. On discharge patient's condition was good.


1996 ◽  
Vol 10 (4) ◽  
pp. 211-216 ◽  
Author(s):  
P. L. Larsen ◽  
M. Tos

Systematic examination of the paranasal sinuses and nasal cavity followed by endoscopic endonasal surgery was performed in 31 cadavers, polyps being found in 13. In all, a total of 27 polyps was found. Only four patients had a case history of allergy or sinusitis. The polyps and their place of origin were documented photographically. A total of 70% of the polyps originated in the ostia, clefts, or recesses. In three patients, polyps originated on the middle turbinate, and in one the agger nasi area, indicating that polyp formation in the ethmoidal sinuses and other paranasal sinuses is secondary to the formation of polyps in the sinus ostia, clefts, and recesses.


Author(s):  
Sandeep Singh Awal ◽  
Som Subhro Biswas ◽  
Sampreet Kaur Awal

Abstract Background Coronavirus disease 2019 (COVID-19) is known to be associated with a myriad of viral, fungal, and bacterial co-infections. Rhino-orbital mucormycosis is a rare angio-invasive fungal infection which has shown a rising trend in the setting of COVID-19. Case presentation We describe the imaging findings in 3 cases of rhino-orbital mucormycosis in patients with history of COVID-19. All cases had varying involvement of paranasal sinuses extending into the orbital compartment while case 3 had intracranial extension of infection. Conclusions Rhino-orbital mucormycosis can have aggressive necrosis of the involved paranasal sinuses and orbits with or without cerebral extension. Hence, the correct diagnosis is imperative as prompt antifungal drugs and surgical debridement can significantly reduce mortality and morbidity.


2021 ◽  
pp. 20-23
Author(s):  
Manish Ranjan ◽  
Vineet Sinha ◽  
Neha Giri ◽  
Abhisek Kishore Dayal ◽  
Surbhi Surbhi ◽  
...  

OBJECTIVE. To study various predisposition for sudden upsurge in mucormycosis in second wave of COVID To study pattern of involvement and spread of disease and to correlate clinicoradiologically METHOD: A prospective observational study was conducted at a tertiary care centre over 2months, involving all patients with mucormycosis of paranasal sinuses with history of corona virus infections and having postive KOH fungal staining on nasal biopsy. RESULT: 30 patients were studied.maxillary and ethmoid sinuses were most affected sinuses.eye involvement was seen in 83.3 percent cases while intracranial extension was seen in 13.3 percent.22 patients gives the history of steroid usage.comorbid condition Diabetes mellitus was being the most common. CONCLUSION:The association between coronavirus and mucormycosis of paranasal sinuses must be given utmost importance.uncontrolled Diabetes and overuse of steroids are main factors.


Author(s):  
M A Aflitonov ◽  
S A Artyushkin ◽  
S A Partsernyak ◽  
A N Mironenko ◽  
A S Partsernyak ◽  
...  

Objective: Identify the diagnostic signs for chronic rhinosinusitis with nasal polyps (CRSwNP & resistant forms) with multimorbid cardiovascular pathology (MCVP) (coronary artery disease (CAd), hypertension, metabolic syndrome (MS). Identify effectiveness of photodynamic therapy in CRSwNP treatment. Design and methods: The study included 75 patients (mean age 35,8±7,93, 39,2% - female,60,8% - male) with CRSwNP and MCVP divided into 3 groups by simple random sampling. Patients in group 1 (n = 27) received standard therapy CRSwNP, hypertension, CAd, NPMd, 8-weeks anti- bacterial and leukotriene receptor antagonists treatment. Surgical interventions history of the last 5 five years: from 1 to 2. Patients in group 2 (n = 28) received standard therapy CRSwNP, hypertension, CAd, NPMd, 8-weeks antibacterial and leukotriene receptor antagonists treatment. Surgical inter- ventions history of the last 5 five years: more than 3. Patients of group 3 (n = 20) received standard therapy CRSwNP, hypertension, CAd, NPMd, 8-weeks antibacterial treatment, 8-weeks leukotriene receptor antagonists treatment and sessions of photodynamic therapy of the paranasal sinuses. Surgical interventions history of the last 5 five years: more than 3. used in the study: complex psychological test methods, ENT and laboratory-instrumental evaluation of the cardiovascular system. Results: depres- sion was detected in 46,3%, 71,9%, 58,3% of patients, (first, second, third groups). Types «non-dipper» and «night-peaker» found in patients 2nd and 3rd groups- corresponds with (CRSwNP & resistant forms). Bone transformation zone as a result of chronic inflammation within the ethmoidal labyrinth and maxillary sinuses identified in the second and third patients group (85% of cases). The use of pho- todynamic therapy in the resistant CRSwNP forms treatment improves the functional indicators of the nasal cavity and paranasal sinuses. Conclusions: Patients with CRSwNP have symptoms of depression and «non-dipper» and «night-peaker» patterns. All CRSwNP patients are defined trigger points with areas of chronic osteitis and odontogenic osteomyelitis. The use of photodynamic therapy for CRSwNP treatment, reduces the number of CRSwNP recurrence.


2021 ◽  
Vol 1 (21) ◽  
Author(s):  
Riyaq A. Farah ◽  
Arturo Poletti ◽  
Aaron Han ◽  
Ramon Navarro

BACKGROUND Osteomas of the paranasal sinuses are benign, slow-growing bone tumors that can cause a variety of clinical features depending on their size and location. Most osteomas are asymptomatic and located in the frontal sinus. In rare cases, they may grow to extend into the cranial or orbital cavities, resulting in atypical presentations. The authors presented an aggressive case of a frontoethmoidal sinus osteoma with intracranial extension of an inflammatory sinonasal polyp. OBSERVATIONS A 30-year-old man with a history of chronic sinusitis presented to the hospital after three episodes of loss of consciousness, chronic worsening of headache, and decreased sense of smell. Rhinoscopic examination showed mucosal polyps arising from the infundibulum and the superior meatus. Computed tomography showed a fibro-osseous mass in the left frontal sinus. Subsequent brain magnetic resonance imaging with and without contrast revealed a large, septated intracranial left frontal lesion approximately 6.5 cm in diameter that was compressing the underlying brain parenchyma. LESSONS Intracranial extension of frontal sinus osteomas can have dire neurological implications. Early detection of lesions obstructing the paranasal sinuses outlet could prevent intracranial extension of the disease. The surgical approach to such tumors may be endonasal, open cranial, or a combination of both.


2019 ◽  
Vol 34 (4) ◽  
pp. 1059-1063
Author(s):  
Vaska Spaskova

The sinuses are bone cavities, coated with mucous membrane (mucosa), filled with air.The bone structure of the human skull is complex and interesting. The large number of paranasal sinuses greatly relieve the weight of the head and thus the load on the spine becomes significantly lower. There are 4 sets of so-called paranasal sinuses: two frontal sinuses, placed in the forehead, above the eyes, two maxillary (jaws), located in the upper jaw, an ethmoidal sinus, built of 18 to 22 small cavities, is located behind the nasal occipital sinus, located behind the nose and under the brain. Rhinosinusitis is divided into: acute, subacute and chronic. Sinusitis is graded according to the etiological factor: fungal, viral, allergic, bacterial, mixed, medicamentous, traumatic, aseptic, septic. The forms of the disease in relation to the nature of the inflammation are: exudative sinusitis, serous form, edematous cataract, purulent, productive, parietal-hyperplastic, cystic, polypous, alternative, hypostomal, necrotic, atrophic, mixed. Allergic rhinitis is an inflammatory response of the nasal mucous membrane to allergenic stimuli, mediated by IgE, characterized by one or more nasal or ocular clinical symptoms. Allergic disease is one of the most common non-communicable diseases and because of its high frequency it is called "21st Century Epidemic". Epidemiological studies suggest that about 25% of the world's population (ARIA) suffer from an allergy. It has been found that 10 to 25% of people have allergic sneezes, the most common manifestation of allergic diseases. The symptoms of rhinitis resemble a cold, but if the cold lasts more than a week and always occurs at the same time of the year, it is most likely allergic rhinitis. Most often sneezing, usually multiple times in a row, runny nose discharge, swelling of blood vessels, which patients feel as clogged nose, sometimes with loss of sense of smell. Allergic rhinitis reduces concentration, causes headaches, affects work ability and is a reason for absenteeism from school or work, and can significantly reduce quality of life. Up to 75% of adults with rhinitis think the disease affects their professional lives. It is often associated with other diseases of the upper respiratory tract, such as inflammation of the sinuses, ear, or nasal polyps. Diagnostic studies are as follows: Carefully taken history of disease, previous history of atopy, character of symptoms (seasonal or year-round, intermittent or persistent symptoms according to ARIA classification), symptoms (clear nasal secretion, nasal congestion, nose, rhinorrhea, sneezing), about 70% of patients with allergic rhinitis also have symptoms of conjunctivitis (redness, tearing, itching), associative diseases (sinusitis, otitis media, asthma), exposure data (especially if we suspect occupational disease), rhinosinusitis nasal mucosa (complete eARL examination indicated at first visit) if patient complains of nasal congestion. The goal is to detect nasal polyps, a pale grayish gray or blue mucous membrane (indicating an allergic reaction, but other types of signs do not rule out allergies). The secretion can vary from purely watery to mucous. An ultrasound examination may check for the presence of secretion in the maxillary sinuses if symptoms indicate acute sinusitis. X-rays of the paranasal sinuses exclude chronic sinusitis, especially if symptoms persist for a long time (months to years). Children should only have sinus X-rays after careful evaluation. Serum IgE and/or skin screening tests are indicated to plan treatment, to use allergen-specific immunotherapy (desensitization), and to diagnose occupational rhinitis.


Lupus ◽  
2021 ◽  
pp. 096120332098345
Author(s):  
Alessandra Ida Celia ◽  
Roberta Priori ◽  
Bruna Cerbelli ◽  
Francesca Diomedi-Camassei ◽  
Vincenzo Leuzzi ◽  
...  

Proteinuria is one of the most typical manifestations of kidney involvement in Systemic Lupus Erythematosus (SLE). We report the case of a 23-year-old woman with a 6-year-long history of SLE presenting with proteinuria after a three-year remission on hydroxychloroquine. Kidney histological examination showed alterations inconsistent with lupus nephritis and suggestive of hydroxychloroquine toxicity or Fabry disease. The latter was confirmed by genetic assay.


Sign in / Sign up

Export Citation Format

Share Document