scholarly journals Coinfection byAspergillusand Zygomycetes Species in a Case of Acute Rhinosinusitis

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Dhara Vaidya ◽  
Parul Shah
Keyword(s):  
Aspergillus Flavus ◽  
Paranasal Sinuses ◽  
Histopathological Examination ◽  
Rapid Identification ◽  
Intracranial Extension ◽  
Acute Rhinosinusitis ◽  
History Of ◽  
Nose And Paranasal Sinuses ◽  
Endoscopic Debridement ◽  
Mycotic Infections

Invasive mycotic infections can be effectively treated if rapid identification of fungus is obtained. We reported a case of coinfection byAspergillusandRhizopussp. involving nose, paranasal sinuses, orbit, and brain in a 68-year-old known hypertensive male. He was presented to ENT OPD with history of fever and intermittent headache since fifteen days along with history of right-sided nasal obstruction and proptosis since seven days. CT scan of brain and paranasal sinuses showed findings of pansinusitis with cellulitic changes in right orbit. MRI confirmed the same along with features of intracranial extension with focal meningitis in right frontotemporal region. Laboratory parameters did not conclude much except for leucocytosis and hyponatremia. Patient was taken for endoscopic debridement from nose and paranasal sinuses, and tissue was sent for microbiological and histopathological examination. Minced tissue was processed, and after 48 hrs of incubation two types of growth were identified, one was yellowish, granular, and powdery consistent withAspergillussp., and another was cottony and woolly consistent withRhizopussp. LCB mount confirmed presence ofAspergillus flavusandRhizopus arrhizus. Patient responded to therapy with IV amphotericin B and surgical debridement. On discharge patient's condition was good.

scholarly journals Saprophytic Mycotic Infections of the Nose and Paranasal Sinuses

2009 ◽  
Vol 1 (1) ◽  
pp. 25-32
Author(s):  
Mohan Kameswaran ◽  
S Raghunandhan
Keyword(s):  
Paranasal Sinuses ◽  
Transplant Recipients ◽  
Susceptible Host ◽  
Opportunistic Fungi ◽  
Post Traumatic ◽  
Nose And Paranasal Sinuses ◽  
The Right ◽  
Mycotic Infections ◽  
Tissue Transplant ◽  
Broad Overview

Abstract The kingdom of fungi is ubiquitous and omnipresent, having prevailed over the tides of time, over numerous decades by adapting to various methods of survival in the susceptible host including humans. Saprophytic fungi derive nutrition from dead and decaying organic matter, with the capacity to flare up in virulence, provided the right opportunity especially when the host immunity is compromised (as in prolonged steroid therapy, diabetes, HIV infection, tissue transplant recipients) or if there is a breech in a vital barrier permitting deeper tissue penetration (postsurgical or post-traumatic). Hence, knowledge about the saprophytic fungal elements dwelling within the nose and paranasal sinuses is paramount for Otolaryngologists worldwide, in order to accurately diagnose and effeciently manage such intriguing cases. This article provides a broad overview of the various opportunistic fungi in rhinology, and highlights the principles of diagnosis and protocols in management.

Rosai—Dorfman disease of the paranasal sinuses

1994 ◽  
Vol 108 (2) ◽  
pp. 152-155 ◽  
Author(s):  
R. T. Gregor ◽  
D. Ninnin
Keyword(s):  
Paranasal Sinuses ◽  
Nasal Polyps ◽  
Fibrous Histiocytoma ◽  
Intracranial Extension ◽  
Unknown Aetiology ◽  
Craniofacial Resection ◽  
Rosai Dorfman Disease ◽  
Kidney Involvement ◽  
History Of ◽  
Tumour Histology

AbstractA 57-year-old man presented with a history of nasal obstruction of five to six years duration. 'Nasal polyps' were removed on several occasions. He had previously had an episode of paraplegia which resolved after the removal of a spinal tumour. Histology from both sites was thought to represent a malignant fibrous histiocytoma. On presentation the patient had computed tomographical (CT) evidence of extensive ethmoidal disease, with threatened intracranial extension. He also had evidence of lung and retroperitoneal disease with pancreas and kidney involvement. The ethmoidal disease was considered potentially lethal and therefore a craniofacial resection was performed. Review of all the histology revealed that the diagnosis was extranodal Rosai–Dorfman disease (sinus histiocytosis). The patient's course is described, and the literature on this disease of unknown aetiology is reviewed.

Comparison of Virtual and Conventional Endoscopy of Nose and Paranasal Sinuses

2003 ◽  
Vol 112 (2) ◽  
pp. 139-142 ◽  
Author(s):  
Lino Di Rienzo ◽  
Guido Coen Tirelli ◽  
Francesco Garaci ◽  
Piergiorgio Turchio ◽  
Marco Guazzaroni
Keyword(s):  
Paranasal Sinuses ◽  
Nasal Fossa ◽  
Noninvasive Technique ◽  
Computed Tomographic ◽  
Fiberoptic Endoscopy ◽  
Sinus Cavity ◽  
History Of ◽  
Group A ◽  
Nose And Paranasal Sinuses ◽  
Group B

We compared computed tomographic virtual rhinosinus endoscopy (VRS) and conventional fiberoptic endoscopy (FE) for the detection of inflammatory-obstructive rhinosinusal disease. We recruited 158 patients; 100 (group A) had inflammatory-obstructive rhinosinus disease, and 58 (group B) had a history of rhinosinus surgery. All patients underwent VRS within 2 to 6 hours of FE, and VRS was able to demonstrate the anatomic details of the nasal fossa and rhinopharynx with a high correspondence to FE. A satisfying representation of anatomic detail was found in both groups A and B. The VRS was able to visualize invasiveness of the endosinusal cavities, which was not accessible to FE. The VRS is a fast, relatively easy, and noninvasive technique that could be integrated into FE or used as an alternative when FE is unfeasible. Because of the ability to explore the sinus cavity, we suggest that virtual rhinosinusoscopy should be considered as the appropriate term, instead of virtual rhinoscopy.

scholarly journals Endoscopic and histological staging: Deciding factors in the treatment of chronic rhinosinusitis

2015 ◽  
Vol 5 (18) ◽  
pp. 115-119 ◽  
Author(s):  
Amalia Neagu ◽  
Codrut Sarafoleanu
Keyword(s):  
Chronic Rhinosinusitis ◽  
Paranasal Sinuses ◽  
Histological Investigation ◽  
Inflammatory Condition ◽  
Therapeutic Decision ◽  
Acute Rhinosinusitis ◽  
Nose And Paranasal Sinuses ◽  
Over Time ◽  
Histological Staging

AbstractChronic rhinosinusitis represents an inflammatory condition of the nose and paranasal sinuses, characterized by two or more symptoms. The diagnosis of acute rhinosinusitis is made, most often, clinically; however, in the case of chronic rhinosinusitis, imaging, bacteriological, as well as the histological investigation are necessary in order to establish the diagnosis and to exclude other diseases that have caused and/or are associated with rhinosinusitis. Different scores (clinical, imagistic) have been described over time, being considered as important factors in the therapeutic decision (surgical or conservative) in patients with chronic rhinosinusitis. The authors present their experience in using and relying on endoscopic and histological scores.

Sinonasal Mucormycosis with Fungal Ball: A Rare Case Report

2014 ◽  
Vol 7 (2) ◽  
pp. 64-66
Author(s):  
Amanjit Bal ◽  
Bhumika Gupta ◽  
Rijuneeta Gupta
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Histopathological Examination ◽  
Inferior Turbinate ◽  
Rapid Identification ◽  
Upper Eyelid ◽  
Fungal Ball ◽  
Rare Case Report ◽  
Rhizopus Sp ◽  
Endoscopic Debridement

ABSTRACT Invasive mycotic infections can be effectively treated if rapid identification of fungus is obtained. We reported a case of coinfection by Aspergillus and Rhizopus sp. involving nose, paranasal sinuses and orbit in a 51 years old male patient diagnosed as diabetic on admission. He presented to ENT OPD with history of drooping of right upper eyelid, decreased vision right eye and deviation of angle of mouth to left side for 12 days. NCCT nose, PNS and orbit showed soft tissue density in right maxillary sinus, ethmoids and destruction of right inferior turbinate. MRI of nose, PNS and orbit revealed hypointense density in right maxillary and ethmoid sinuses on T1-weighted images and on T2-weighted; it was hyperintense. Patient underwent endoscopic debridement under general anesthesia and tissue was sent for microbiological and histopathological examination which confirmed presence of Aspergillus and Rhizopus. Patient responded to therapy with IV amphotericin B and surgical debridement. On discharge patient's condition was good. How to cite this article Gupta R, Gupta B, Bal A, Gupta AK. Sinonasal Mucormycosis with Fungal Ball: A Rare Case Report. Clin Rhinol An Int J 2014;7(2):64-66.

scholarly journals Rhino-orbital mucormycosis in COVID-19 patients—a new threat?

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Sandeep Singh Awal ◽  
Som Subhro Biswas ◽  
Sampreet Kaur Awal
Keyword(s):  
Fungal Infection ◽  
Invasive Fungal Infection ◽  
Paranasal Sinuses ◽  
Correct Diagnosis ◽  
Antifungal Drugs ◽  
Intracranial Extension ◽  
Imaging Findings ◽  
Case Presentation ◽  
Mortality And Morbidity ◽  
History Of

Abstract Background Coronavirus disease 2019 (COVID-19) is known to be associated with a myriad of viral, fungal, and bacterial co-infections. Rhino-orbital mucormycosis is a rare angio-invasive fungal infection which has shown a rising trend in the setting of COVID-19. Case presentation We describe the imaging findings in 3 cases of rhino-orbital mucormycosis in patients with history of COVID-19. All cases had varying involvement of paranasal sinuses extending into the orbital compartment while case 3 had intracranial extension of infection. Conclusions Rhino-orbital mucormycosis can have aggressive necrosis of the involved paranasal sinuses and orbits with or without cerebral extension. Hence, the correct diagnosis is imperative as prompt antifungal drugs and surgical debridement can significantly reduce mortality and morbidity.

scholarly journals MUCORMYCOSIS UBIQUITOUS FUNGUS THRIVING IN IMMUNOCOMPROMISED COVID PATIENT IN PATNA

2021 ◽  
pp. 20-23
Author(s):  
Manish Ranjan ◽  
Vineet Sinha ◽  
Neha Giri ◽  
Abhisek Kishore Dayal ◽  
Surbhi Surbhi ◽  
...  
Keyword(s):  
Paranasal Sinuses ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Intracranial Extension ◽  
Virus Infections ◽  
Tertiary Care Centre ◽  
History Of ◽  
Ethmoid Sinuses ◽  
Second Wave ◽  
Nasal Biopsy

OBJECTIVE. To study various predisposition for sudden upsurge in mucormycosis in second wave of COVID To study pattern of involvement and spread of disease and to correlate clinicoradiologically METHOD: A prospective observational study was conducted at a tertiary care centre over 2months, involving all patients with mucormycosis of paranasal sinuses with history of corona virus infections and having postive KOH fungal staining on nasal biopsy. RESULT: 30 patients were studied.maxillary and ethmoid sinuses were most affected sinuses.eye involvement was seen in 83.3 percent cases while intracranial extension was seen in 13.3 percent.22 patients gives the history of steroid usage.comorbid condition Diabetes mellitus was being the most common. CONCLUSION:The association between coronavirus and mucormycosis of paranasal sinuses must be given utmost importance.uncontrolled Diabetes and overuse of steroids are main factors.

scholarly journals Angiosarcoma of the nasal cavity and paranasal sinuses: a rare case report

2017 ◽  
Vol 3 (3) ◽  
pp. 735
Author(s):  
Jyoti Singh ◽  
Jai Lal Davessar ◽  
Sumit Prinja ◽  
Nitin Arora
Keyword(s):  
Paranasal Sinuses ◽  
Rare Case ◽  
Excisional Biopsy ◽  
Surgical Removal ◽  
Left Nostril ◽  
Vascular Phenotype ◽  
Rare Case Report ◽  
History Of ◽  
Poorly Differentiated ◽  
Nose And Paranasal Sinuses

<p class="abstract">Angiosarcomas are the malignant neoplasias of vascular phenotype whose constituent tumor cells have endothelial features. They account for less than 1% of all sinonasal tract malignancies. A case of 65 year old male with a 6 months history of spontaneous epistaxis and a nasal mass lesion presented to the OPD. On physical examination, a polypoidal purplish tumor of 6 × 5 cm was identified. A NCCT scan of nose and paranasal sinuses showed a nonenhanced tumor in the left nostril in maxillary, ethmoid, sphenoid and frontal sinus. An excisional biopsy revealed a poorly differentiated angiosarcoma. Surgical removal of the lesion was advised which was refused by the patient.</p><p class="abstract">Patient was put on the radiation therapy. Angiosarcoma of the nose and paranasal sinuses is an extremely rare tumor. Recurrences are common due to incomplete excision or mutiflocality.</p>

Bilateral transitional-type inverted papilloma of the nose and paranasal sinuses

1982 ◽  
Vol 96 (3) ◽  
pp. 281-288 ◽  
Author(s):  
P. Chatterji ◽  
I. Friedmann ◽  
N. K. Soni ◽  
R. L. Solanki ◽  
I. N. Ramdeo
Keyword(s):  
Paranasal Sinuses ◽  
Surgical Excision ◽  
Inverted Papilloma ◽  
Present Communication ◽  
Complete Surgical Excision ◽  
Transitional Type ◽  
History Of ◽  
Uncommon Case ◽  
Nose And Paranasal Sinuses ◽  
Salient Features

SummaryAn uncommon bilateral transitional-type inverted papilloma of the nose and paranasal sinuses is presented, and the salient features of the lesion are discussed. The patient is well and without any signs of recurrence in either side of the nose more than two years after the first diagnosis and complete surgical excision of both tumours.Commonly unilateral, this tumour may occasionally be bilateral. In the present communication an uncommon case of bilateral inverted transitional-type papilloma, with a long history of allergy, is described with some comments on its pathogenesis.

scholarly journals Fungal multisinusitis with intracranial extension

1970 ◽  
Vol 39 (136) ◽  
pp. 354-356
Author(s):  
N Thapa ◽  
B K Sinha ◽  
RCM Amatya ◽  
P Shrivastav ◽  
B Pradhan ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Ct Scan ◽  
Paranasal Sinuses ◽  
Intracranial Extension ◽  
Healthy Patient ◽  
Nose And Paranasal Sinuses

Aspergillosis is the commonest fungal infection of nose and paranasal sinuses. Itsinvasive form is rare in a healthy patient. A case of fungal multisinusitis with intracranialextension with characteristic computerized tomographic finding is reported.Key Words: Aspergillosis, intracranial extension, CT scan,external frontoethmoidectomy.

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