Influence of lipoproteins and fibrinogen on pathogenesis of sudden sensorineural hearing loss

2010 ◽  
Vol 125 (3) ◽  
pp. 258-261 ◽  
Author(s):  
Z Oreskovic ◽  
D Shejbal ◽  
G Bicanic ◽  
B Kekic
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Low Density Lipoprotein ◽  
Plasma Concentrations ◽  
Density Lipoprotein ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol

AbstractAim:To evaluate the relationship between lipoproteins, fibrinogen and sudden sensorineural hearing loss in a Croatian population. Since pathological derangement of lipoproteins and fibrinogen could be one of the causes of sudden sensorineural hearing loss, we hypothesised that patients with sudden sensorineural hearing loss would have more abnormal fibrinogen and lipoprotein concentrations, compared with subjects with normal hearing.Methods:Plasma concentrations of cholesterol, fibrinogen and triglycerides in patients with sudden sensorineural hearing loss were compared with those in a control group (i.e. subjects with normal hearing function).Results:Patients with sudden sensorineural hearing loss had significantly higher plasma concentrations of cholesterol and low density lipoprotein cholesterol, compared with controls.Conclusion:Higher cholesterol and low density lipoprotein cholesterol concentrations were found in patients with sudden sensorineural hearing loss, within a Croatian population. Cholesterol and low density lipoprotein cholesterol concentrations may be important factors in the pathogenesis of sudden sensorineural hearing loss, and should be assessed during the investigation of patients with this condition.

scholarly journals Hubungan Kadar Low Density Lipoprotein Dengan Gangguan Pendengaran Sensorineural

2020 ◽  
Vol 5 (2) ◽  
pp. 115-127
Author(s):  
Nurfadhilah Amini Nasution ◽  
Muhammad Edy Syahputra Nasution ◽  
Siti Masliana Siregar ◽  
Des Suryani
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Low Density Lipoprotein ◽  
Cranial Nerves ◽  
Density Lipoprotein ◽  
Sensorineural Hearing ◽  
Low Density ◽  
Research Subjects ◽  
Chi Square ◽  
Cross Sectional

Abnormalities of lipid metabolism in hyperlipidemia are the cause of atherosclerotic plaque in the inner ear and cranial nerves VIII, which can cause sensorineural hearing loss. Based on previous research, this theory is still questionable. Objective: To determine the relationship of LDL levels with sensorineural hearing loss. Method: This study is an analytic study with a cross-sectional approach. The research sample was taken based on a categorical descriptive formula with a large sample of 38 people. The data obtained is the result of laboratory tests, physical examination of the ears, nose and throat and audiometry examination of pure tone. This research was conducted at Medan Haji General Hospital and Putri Hijau Hospital II Medan. The number of research subjects was determined using consecutive sampling techniques. Data were analyzed using chi square test statistics. Results: There was a significant correlation of LDL levels with sensorineural hearing loss with a value of p = 0.001. The highest age in this study was 50-60 years of age, the most sex was female, the highest degree of hearing loss was moderateConclusion: There is a significant relationship between LDL levels with sensorineural hearing loss.   Keywords: Audiometry, Hearing Loss, Sensorineural Hearing Loss, Low Density Lipoprotein, Lipid Profile  

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