Pyriform aperture enlargement in all aspects

2017 ◽  
Vol 131 (6) ◽  
pp. 476-479 ◽  
Author(s):  
E Esen ◽  
N Bayar Muluk ◽  
N Altintoprak ◽  
K Ipci ◽  
C Cingi

AbstractBackground:The pyriform aperture comprises the central area of facial bone structure. It is formed by the free corners of the nasal bone and the frontal processes of the maxillae, which articulate with each other at the nasomaxillary suture lines. Congenital nasal pyriform aperture stenosis might be linked to various craniofacial problems. This review presents all aspects of pyriform aperture stenosis and enlargement.Methods:A literature search was conducted. Pyriform aperture definition, nasal development, congenital nasal pyriform aperture stenosis and pyriform aperture enlargement were reviewed.Results:One of the most common abnormalities is holoprosencephaly, which is a midline developmental deficiency that may also be present in combination with facial clefting. The aetiology of nasal pyriform aperture stenosis remains unclear. When diagnosed, the choice of treatment is between non-surgical and operative methods, depending on the seriousness of the problem. Provided the sufferer can maintain a secure air passage with the help of specialised medical procedures and respiratory tract adjuvants, operative therapy may be delayed.Conclusion:The operative outcomes are extremely good, and the prognosis relies mainly on coexisting neural and endocrine problems. This paper evaluates the nasal pyriform aperture in detail.

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Emanuela Sitzia ◽  
Sara Santarsiero ◽  
Filippo Maria Tucci ◽  
Giovanni De Vincentiis ◽  
Angela Galeotti ◽  
...  

Abstract Background Congenital nasal pyriform aperture stenosis (CNPAS) is a rare condition that may occur alone or as part of a multi-formative syndrome. Management remains difficult. There is no specific treatment protocol. Traditional surgery would be anachronistic; a non-invasive or minimally invasive therapeutic option is required. However, the rarity of the disease and the infantile context render randomised clinical trials difficult. Case presentation We present the case of a one-month-old Caucasian boy with CNPAS. He presented to the Emergency Department of the Bambino Gesù Pediatric Hospital with nasal obstruction, noisy breathing, feeding difficulties, and suspected sleep apnoea. During hospitalisation, he underwent overnight pulse oximetry, airway endoscopy, and maxillofacial computed tomography (CT); the final diagnosis was CNPAS with moderate obstructive sleep apnoea syndrome. We successfully treated the patient using an innovative strategy that involved collaboration between ear-nose-and-throat surgeons and orthodontists. Conclusions A combination of minimally invasive balloon surgery and placement of a palatal device may successfully treat CNPAS; it may also treat other types of nasal bone stenosis. Future studies may allow the development of practice consensus treatment strategies.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Abdul Shukor Tajul Ariff ◽  
Ima Nirwana Soelaiman ◽  
J. Pramanik ◽  
Ahmad Nazrun Shuid

Testosterone replacement is the choice of treatment in androgen-deficient osteoporosis. However, long-term use of testosterone is potentially carcinogenic.Eurycoma longifolia(EL) has been reported to enhance testosterone level and prevent bone calcium loss but there is a paucity of research regarding its effect on the bone structural parameters. This study was conducted to explore the bone structural changes following EL treatment in normal and androgen-deficient osteoporosis rat model. Thirty-six male Sprague-Dawley rats aged 12 months were divided into normal control, normal rat supplemented with EL, sham-operated, orchidectomised-control, orchidectomised with testosterone replacement, and orchidectomised with EL supplementation groups. Testosterone serum was measured both before and after the completion of the treatment. After 6 weeks of the treatment, the femora were processed for bone histomorphometry. Testosterone replacement was able to raise the testosterone level and restore the bone volume of orchidectomised rats. EL supplementation failed to emulate both these testosterone actions. The inability of EL to do so may be related to the absence of testes in the androgen deficient osteoporosis model for EL to stimulate testosterone production.


2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Asieh Zamani Naser ◽  
Mariyya Panahi Boroujeni

Background. The aim of the present study was to have normative data of nasal bone thickness for use before reconstructive surgery and nasal augmentation through radiography analysis. Methods and Materials. In this descriptive-analytical study, 74 patients were selected from people referred to Radiology Department of Isfahan University for CBCT examination in 2012. Patients with a history of nasal surgery or facial trauma and known congenital anomaly were excluded from the study. Height of nasal bone and width of pyriform aperture and nasal bone thickness in lateral and medial osteotomy line were measured. All these measurements were repeated by two radiologists; finally one sample t-test was performed. Results. The mean thickness of nasal bone on the lateral osteotomy line was 1.92 ± 0.29 mm in females and 1.73 ± 0.32 mm in males (P value = 0.39). The mean thickness of medial osteotomy line was 1.63 ± 0.47 mm in females and 1.94 ± 0.19 mm in males (P value = 0.31). The mean length of nasal bone was 23.5 ± 3.34 mm in females and 25.7 ± 2.96 mm in males (P value = 0.11). The mean width of pyriform aperture was 23.77 ± 2.58 mm in females and 25.67 ± 1.79 mm in males (P value = 0.25). Conclusions. The dimensions of nasal pyramid are known to be significant in choosing suitable osteotome size for reducing surgery side effect. Our results can be used for preoperative estimation of nasal bone dimension of people undergoing reconstructive surgery and augmentation.


2014 ◽  
Vol 25 (6) ◽  
pp. 2214-2219 ◽  
Author(s):  
Neslihan Yüzbaşioğlu ◽  
Mehmet Tuğrul Yilmaz ◽  
Aynur Emine Çicekcibasi ◽  
Muzaffer Şeker ◽  
Mehmet Emin Sakarya

2021 ◽  
Author(s):  
Sara Santarsiero

Abstract BackgroundCongenital nasal pyriform aperture stenosis (CNPAS) is a rare condition isolated or inserted in a multi-formative syndrome, which still encounters management difficulties. There are no specific treatment protocols and the use of traditional surgery represents an anachronism since cognitive assumptions and non-invasive or minimally invasive therapeutic innovations would currently be available. However, the rarity of the disease and the infantile context makes RCTs difficult to process. Case presentationWe expose the case of a one-month-old caucasian male infant suffering from CNPAS. The patient presented to the Emergency Department of the Bambino Gesù Pediatric Hospital with a clinical picture characterized by nasal obstruction, noisy breathing, feeding difficulties and suspected sleep apnea. During hospitalization he underwent overnight pulse oximetry, airway endoscopy and maxillofacial CT with a final diagnosis of CNPAS with moderate obstructive sleep apnea. We treated him successfully through an innovative therapeutic strategy that required the collaboration of a team of ENT surgeons and orthodontists.ConclusionsThe combination of minimally invasive balloon surgery and the application of a palatal device may represent a successful strategy for patients with CNPAS, probably also applicable to other types of nasal bone stenosis. Future studies may allow the definition of treatment strategies of these pathologies, we hope in the context of novel practical guidelines.


2020 ◽  
Vol 36 (05) ◽  
pp. 499-504
Author(s):  
Charmain Liling Zhao ◽  
Suzanne Teo ◽  
Lisa Lim ◽  
Sandeep Uppal

AbstractOsteotomies in rhinoplasty are performed to correct deformities in nasal contour. The size of osteotome used is dictated by the thickness of the bony nasal pyramid along the osteotomy route. The aim of this study is to determine whether nasal bony dimensions differ between different ethnic groups in Singapore. Randomly selected patients' computed tomography (CT) scans of the face performed between the years 2010 to 2013 in our institution (Khoo Teck Puat Hospital) were evaluated. The setting was a tertiary government hospital. CT images of 309 patients (233 Chinese [147 males, 86 females], 32 Malays [16 males, 16 females], and 44 Indians [33 males, 11 females]) were evaluated. Anthropomorphic measurements of the nasal bone along the track of the lateral, medial, and intermediate osteotomies, as well as the nasal bone length and pyriform aperture width were measured on the CT images by two independent observers. Statistical analysis was performed using Student's t-test and two-way analysis of variance (ANOVA) test. There was no significant difference between the nasal pyramid bone thickness between different ethnicities along the osteotomy tracks (p > 0.05; degrees of freedom [df] = 2). However, there was a significant difference between males and females of the same ethnicity at the low level of the lateral osteotomy (p = 0.003) and the midlevel (p = 0.002) and high-level (p = 0.004) of the intermediate osteotomy. There was a statistically significant difference in nasal pyramid length (p < 0.05, df = 2) and pyriform aperture width (p < 0.05, df = 2) among the races and between the genders (p < 0.05). The mean difference in nasal pyramid length of 2.54 mm and pyriform aperture width of 1.89 mm was particularly significant between the Chinese and the Indians. Gender and ethnic differences in nasal bony dimensions should be considered in surgical planning for rhinoplasty.


Author(s):  
Jiang Xishan

This paper reports the growth step pattern and morphology at equilibrium and growth states of (Mn,Fe)S single crystal on the wall of micro-voids in ZG25 cast steel by using scanning electron microscope. Seldom report was presented on the growth morphology and steppattern of (Mn,Fe)S single crystal.Fig.1 shows the front half of the polyhedron of(Mn,Fe)S single crystal,its central area being the square crystal plane,the two pairs of hexagons symmetrically located in the high and low, the left and right with a certain, angle to the square crystal plane.According to the symmetrical relationship of crystal, it was defined that the (Mn,Fe)S single crystal at equilibrium state is tetrakaidecahedron consisted of eight hexagonal crystal planes and six square crystal planes. The macroscopic symmetry elements of the tetrakaidecahedron correpond to Oh—n3m symmetry class of fcc structure,in which the hexagonal crystal planes are the { 111 } crystal planes group,square crystal plaits are the { 100 } crystal planes group. This new discovery of the (Mn,Fe)S single crystal provides a typical example of the point group of Oh—n3m.


2006 ◽  
Vol 5 (12) ◽  
pp. 30
Author(s):  
KERRI WACHTER
Keyword(s):  

Author(s):  
Zafer Sahin ◽  
Alpaslan Ozkurkculer ◽  
Omer Faruk Kalkan ◽  
Ahmet Ozkaya ◽  
Aynur Koc ◽  
...  

Abstract. Alterations of essential elements in the brain are associated with the pathophysiology of many neuropsychiatric disorders. It is known that chronic/overwhelming stress may cause some anxiety and/or depression. We aimed to investigate the effects of two different chronic immobilization stress protocols on anxiety-related behaviors and brain minerals. Adult male Wistar rats were divided into 3 groups as follows ( n = 10/group): control, immobilization stress-1 (45 minutes daily for 7-day) and immobilization stress-2 (45 minutes twice a day for 7-day). Stress-related behaviors were evaluated by open field test and forced swimming test. In the immobilization stress-1 and immobilization stress-2 groups, percentage of time spent in the central area (6.38 ± 0.41% and 6.28 ± 1.03% respectively, p < 0.05) and rearing frequency (2.75 ± 0.41 and 3.85 ± 0.46, p < 0.01 and p < 0.05, respectively) were lower, latency to center area (49.11 ± 5.87 s and 44.92 ± 8.04 s, p < 0.01 and p < 0.01, respectively), were higher than the control group (8.65 ± 0.49%, 5.37 ± 0.44 and 15.3 ± 3.32 s, respectively). In the immobilization stress-1 group, zinc (12.65 ± 0.1 ppm, p < 0.001), magnesium (170.4 ± 1.7 ppm, p < 0.005) and phosphate (2.76 ± 0.1 ppm, p < 0.05) levels were lower than the control group (13.87 ± 0.16 ppm, 179.31 ± 1.87 ppm and 3.11 ± 0.06 ppm, respectively). In the immobilization stress-2 group, magnesium (171.56 ± 1.87 ppm, p < 0.05), phosphate (2.44 ± 0.07 ppm, p < 0.001) levels were lower, and manganese (373.68 ± 5.76 ppb, p < 0.001) and copper (2.79 ± 0.15 ppm, p < 0.05) levels were higher than the control group (179.31 ± 1.87 ppm, 3.11 ± 0.06 ppm, 327.25 ± 8.35 ppb and 2.45 ± 0.05 ppm, respectively). Our results indicated that 7-day chronic immobilization stress increased anxiety-related behaviors in both stress groups. Zinc, magnesium, phosphate, copper and manganese levels were affected in the brain.


Swiss Surgery ◽  
1999 ◽  
Vol 5 (3) ◽  
pp. 116-121 ◽  
Author(s):  
Schmassmann

Surgical resection is the first choice of treatment for patients with hepatocellular (HCC) and cholangiocellular carcinomas. Prolongation of survival is, however, the only realistic goal for most patients, which can be often achieved by nonsurgical therapies. Inoperable patients with large or multiple HCCs are usually treated with transarterial chemoembolization (TACE) with lipiodol in combination with a chemotherapeutic drug and gelfoam. Three-year survival depends on the stage of the disease and is about 20%. Patients with earlier tumor stages (one or two tumor nodules less than 3cm in size) are suitable for treatment with percutaneous ethanol injection (PEI) alone or in combination with TACE. Several studies have shown that in these early stages, the 3-year survival rate is approximately 55%-70% in the actively treated patients which is significantly higher than in untreated patients. In advanced stages of the disease, TACE and PEI have no effect on survival and should not be performed. Some of these patients have been successfully treated with octreotide. Patients with inoperable cholangiocellular carcinoma are treated by endoscopic or percutaneous stent placement. If stenting does not achieve adequate biliary drainage, multidisciplinary therapy including internal / external radiotherapy or photodynamic therapy should be considered in patients with potential long-term survival. In conclusion, nonresectional therapies play an essential role in the therapy of inoperable hepato- and cholangiocellular carcinomas as they lead to satisfactory survival. Multidisciplinary therapy appears to be the current trend of management.


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