Post-conflict initiatives and the exclusion of conflict-affected young people in northern Uganda

2021 ◽  
Vol 59 (1) ◽  
pp. 21-39
Author(s):  
Alina Dixon
Keyword(s):  
Young People ◽  
Family System ◽  
Social Systems ◽  
Structure And Function ◽  
Northern Uganda ◽  
Social Environments ◽  
Post Conflict ◽  
The Family ◽  
And Function

ABSTRACTYoung people are among the most severely impacted by conflict and as such many post-conflict initiatives are aimed at assisting them. Yet the impacts of these initiatives on young people's ability to successfully overcome the adversity they faced during conflict are not fully understood. This paper attempts to examine these impacts by conceptualising post-conflict initiatives as enmeshed within young people's social environments. It argues that post-conflict initiatives are intimately connected to broader processes of exclusion from social systems such as the family. While these systems had previously served to protect young people against adversity, conflict and post-conflict initiatives have disrupted their ability to continue this mission. In particular, the structure and function of the family system are examined to demonstrate the types of disruptions that have taken place that have ultimately negatively impacted the landscape in which young people develop.

scholarly journals Exotoxins of Staphylococcus aureus

2000 ◽  
Vol 13 (1) ◽  
pp. 16-34 ◽  
Author(s):  
Martin M. Dinges ◽  
Paul M. Orwin ◽  
Patrick M. Schlievert
Keyword(s):  
Staphylococcus Aureus ◽  
Toxic Shock Syndrome ◽  
Molecular Basis ◽  
Molecular Mechanisms ◽  
Food Poisoning ◽  
Structure And Function ◽  
Toxic Shock ◽  
The Family ◽  
Toxic Shock Syndrome Toxin ◽  
And Function

SUMMARY This article reviews the literature regarding the structure and function of two types of exotoxins expressed by Staphylococcus aureus, pyrogenic toxin superantigens (PTSAgs) and hemolysins. The molecular basis of PTSAg toxicity is presented in the context of two diseases known to be caused by these exotoxins: toxic shock syndrome and staphylococcal food poisoning. The family of staphylococcal PTSAgs presently includes toxic shock syndrome toxin-1 (TSST-1) and most of the staphylococcal enterotoxins (SEs) (SEA, SEB, SEC, SED, SEE, SEG, and SEH). As the name implies, the PTSAgs are multifunctional proteins that invariably exhibit lethal activity, pyrogenicity, superantigenicity, and the capacity to induce lethal hypersensitivity to endotoxin. Other properties exhibited by one or more staphylococcal PTSAgs include emetic activity (SEs) and penetration across mucosal barriers (TSST-1). A detailed review of the molecular mechanisms underlying the toxicity of the staphylococcal hemolysins is also presented.

scholarly journals Phylogeny of the Serpin Superfamily: Implications of Patterns of Amino Acid Conservation for Structure and Function

2000 ◽  
Vol 10 (12) ◽  
pp. 1845-1864
Author(s):  
James A. Irving ◽  
Robert N. Pike ◽  
Arthur M. Lesk ◽  
James C. Whisstock
Keyword(s):  
Sequence Data ◽  
Initial Point ◽  
Structure And Function ◽  
Conserved Residues ◽  
Consensus Analysis ◽  
The Family ◽  
Protein Sequence Data ◽  
And Function ◽  
Conserved Amino Acids ◽  
Genome Projects

We present a comprehensive alignment and phylogenetic analysis of the serpins, a superfamily of proteins with known members in higher animals, nematodes, insects, plants, and viruses. We analyze, compare, and classify 219 proteins representative of eight major and eight minor subfamilies, using a novel technique of consensus analysis. Patterns of sequence conservation characterize the family as a whole, with a clear relationship to the mechanism of function. Variations of these patterns within phylogenetically distinct groups can be correlated with the divergence of structure and function. The goals of this work are to provide a carefully curated alignment of serpin sequences, to describe patterns of conservation and divergence, and to derive a phylogenetic tree expressing the relationships among the members of this family. We extend earlier studies by Huber and Carrell as well as by Marshall, after whose publication the serpin family has grown functionally, taxonomically, and structurally. We used gene and protein sequence data, crystal structures, and chromosomal location where available. The results illuminate structure–function relationships in serpins, suggesting roles for conserved residues in the mechanism of conformational change. The phylogeny provides a rational evolutionary framework to classify serpins and enables identification of conserved amino acids. Patterns of conservation also provide an initial point of comparison for genes identified by the various genome projects. New homologs emerging from sequencing projects can either take their place within the current classification or, if necessary, extend it.

scholarly journals A qualitative study of parents’ and their child’s experience of a medial epicondyle fracture

2021 ◽  
Vol 2 (6) ◽  
pp. 359-364
Author(s):  
Kinga Papiez ◽  
Elizabeth Tutton ◽  
Emma E. Phelps ◽  
Janis Baird ◽  
Matthew L. Costa ◽  
...  
Keyword(s):  
Young People ◽  
Controlled Trial ◽  
Qualitative Interviews ◽  
Medial Epicondyle ◽  
Competitive Sports ◽  
Randomized Controlled ◽  
The Family ◽  
And Function ◽  
The Impact ◽  
Medial Epicondyle Fracture

Aims The aim of this study was to explore parents and young people’s experience of having a medial epicondyle fracture, and their thoughts about the uncertainty regarding the optimal treatment. Methods Families were identified after being invited to participate in a randomized controlled trial of surgery or no surgery for displaced medial epicondyle fractures of the humerus in children. A purposeful sample of 25 parents (22 females) and five young people (three females, mean age 11 years (7 to 14)) from 15 UK hospitals were interviewed a mean of 39 days (14 to 78) from injury. Qualitative interviews were informed by phenomenology and themes identified to convey participants’ experience. Results The results identify parents’ desire to do the best for their child expressed through two themes: 1) ‘uncertainty’ (being uncertain about the best treatment option); and 2) ‘facilitating recovery’ (sharing the experience). Parents and young people were shocked when confronted with uncertainty about treatment and they felt responsible for the decision. They searched for further information, drew on their own experience, and struggled to weigh up risks of the treatments. Discussion with surgeons provided crucial support for decision-making, and young people were involved to a varying degree. In facilitating recovery, parents balanced increasing activity with protecting their child, but lacked knowledge about pain management, and how to improve strength and function of the arm. They hoped for a return to normal, including competitive sports. Conclusion Surgeons are aware of the impact of injury on children and their parents; however, they may be less aware of the turmoil created by treatment uncertainty. Confident surgeons who appreciate and contextualize the importance of pre-existing experience and beliefs are best placed to help the family develop confidence to embrace uncertainty, particularly regarding participation in clinical trials. Cite this article: Bone Jt Open 2021;2(6):359–364.

Lost in Transition: Determining HIV Prevalence and Related Vulnerabilities Among Young People in Post-conflict Northern Uganda

2012 ◽  
Author(s):  
Sheetal H. Patel ◽  
Martin T. Schechter ◽  
Herbert Muyinda ◽  
Noah Kiwanuka ◽  
Nelson K. Sewankambo ◽  
...  
Keyword(s):  
Young People ◽  
Hiv Prevalence ◽  
Northern Uganda ◽  
Post Conflict

Mammalian social systems: Structure and function

1976 ◽  
Vol 24 (2) ◽  
pp. 261-274 ◽  
Author(s):  
J.H. Crook ◽  
J.E. Ellis ◽  
J.D. Goss-Custard
Keyword(s):  
Social Systems ◽  
Structure And Function ◽  
And Function

A Multilevel Social Systems Practice Model for Working with AFDC JOBS Program Clients

1992 ◽  
Vol 73 (1) ◽  
pp. 3-13 ◽  
Author(s):  
Nancy R. Vosler ◽  
Martha N. Ozawa
Keyword(s):  
Welfare Reform ◽  
Family Support ◽  
Family System ◽  
Social Systems ◽  
System Change ◽  
Practice Model ◽  
National State ◽  
Local Neighborhood ◽  
Systems Practice ◽  
The Family

A multilevel social systems practice model is presented for work with individuals and families affected by the Family Support (“welfare reform”) Act of 1988. Discussion of issues in the implementation of the JOBS progam focuses on six social systems levels: national, state, local, neighborhood, family, and individual. A specific example of contrasting programs at local and neighborhood levels highlights differential approaches to facilitating individual and/or family system change.

The family in the view of Israeli adolescents in foster care

2016 ◽  
Vol 18 (2) ◽  
pp. 201-221
Author(s):  
Michal Mahat-Shamir ◽  
Bilha Davidson Arad ◽  
Guy Shilo ◽  
Ronit Adler ◽  
Ronit D Leichtentritt
Keyword(s):  
Foster Care ◽  
Young People ◽  
Family Life ◽  
Family Of Origin ◽  
Family System ◽  
Genetic System ◽  
Social Expectation ◽  
Biological Parents ◽  
The Social ◽  
The Family

Summary This qualitative study explores the unique views about the family system held by adolescents who have spent years in foster care in Israel. This inductive study is among the few to address the unheard views held, and the salient challenges faced, by adolescents who have not grown up in their biological parents’ home, with a focus on their view of the family. Findings Participants’ demonstrated conflicting, polarizing perceptions of the family: (a) family is a genetic system: blood is thicker than water; (b) the family system is constructed and limited by terminology; and (c) communication is essential to family life. Applications While the first two themes highlighted the participants’ family of origin as their “true family” the last theme emphasized on the foster family as their “true” family system. Synthesis between these views could not be achieved as informants embraced the social expectation perceiving the family as one. Raising social and professional awareness about the difficulties these young people face partly because of an exclusive social view of the family lies in the sphere of interest and the social work professional expertise.

— Zur Morphologie und Funktion des — Helodiden-Aedoeagus (Col.)1

1972 ◽  
Vol 3 (2) ◽  
pp. 81-119 ◽  
Author(s):  
Tord Nyholm
Keyword(s):  
Distal Part ◽  
Comparative Morphology ◽  
Structure And Function ◽  
The Other ◽  
Gradual Change ◽  
Median Lobe ◽  
Initial Form ◽  
The Family ◽  
Different Types ◽  
And Function

AbstractThe structure and function of the aedeagus were investigated in 9 genera of the family Helodidae, most thoroughly in Helodes and Cyphon. On the basis of this investigation, the different types of tegmen and penis represented within the family are described. The tegmen of the Helodidae, which is either entirely devoid of a sclerotized "basal piece" or possesses only rudiments of such, may be divided into three main types; in addition there are a few quite aberrant cases. The penis (median lobe), more interesting from the standpoint of comparative morphology, is extremely diversified. A separation between two main types could however be maintained: one represented by genus Helodes alone, the other by all remaining genera. The Helodes type is more primitive, though at the same time rather specialized in certain details. The second penis type is still more specialized. Its main characteristic is a separate triangular sclerite (a "trigonium") situated ventrally in the distal part of penis. In certain genera it is cleft medially into a pair of moveable appendages ("prosthemata"). A splitting of the penis apex into two lobes ("parameroids") occurs in most species of Helodes, but also among the majority of remaining genera. The evolution of the penis from a supposed primitive initial form towards the Helodes type on one side and the highly specialized type represented by certain species of Cyphon on the other, is outlined and discussed. The importance of a gradual change of the copulatory method for this evolution is particularly stressed. The morphology of the aedeagus as basis for the systematics of the Helodidae is briefly treated. The investigation was also extended to cover representatives of other families, generally regarded as related to the Helodidae. Most of them possess an aedeagus of a rather primitive trilobed type. Deviating from this pattern are the Dascillidae, with the penis completely cleft into one dorsal and one ventral sclerite, and also the Psephenidae. In this family, the penis is supplied with a separate sclerite, apparently homologous with the "trigonium" of the Helodidae and with a similar evolution.

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