Premotor systems, language-related neurodynamics, and cetacean communication

1998 ◽  
Vol 21 (4) ◽  
pp. 517-518
Author(s):  
Gary Goldberg ◽  
Roberta Brooks
Keyword(s):  
Cerebral Cortex ◽  
Speech Production ◽  
Language Production ◽  
Cetacean Species ◽  
Target Article ◽  
Significant Divergence ◽  
Content Theory ◽  
Production Mechanisms ◽  
Motor Acts

The frame/content theory of speech production is restricted to output mechanisms in the target article; we suggest that these ideas might best be viewed in the context of language production proceeding as a coordinated dynamical whole. The role of the medial premotor system in generating frames matches the important role it may play in the internally dependent timing of motor acts. The proposed coevolution of cortical architectonics and language production mechanisms suggests a significant divergence between primate and cetacean species corresponding to major differences in areal differentiation trends in cerebral cortex.

scholarly journals The role of language production mechanisms in children's sentence repetition: Evidence from an inflectionally rich language

2017 ◽  
Vol 39 (2) ◽  
pp. 303-325 ◽  
Author(s):  
SONALI NAG ◽  
MARGARET J. SNOWLING ◽  
JELENA MIRKOVIĆ
Keyword(s):  
Language Production ◽  
Developmental Disorders ◽  
Native Speakers ◽  
Sentence Length ◽  
Clinical Tool ◽  
Speech Error ◽  
Sentence Repetition ◽  
Error Analyses ◽  
Production Mechanisms

ABSTRACTWe examine the role of language production mechanisms in sentence repetition, a task widely used as a diagnostic tool in developmental disorders. We investigate sentence repetition in 5- to 8-year-old native speakers of Kannada, an inflectionally rich language of India. The inflectional characteristics of the language make it an ideal testing ground for exploring the engagement of grammatical and phonological encoding processes. We presented active, passive, and embedded sentences and, in a subset of the material, we also manipulated sentence length. Using accuracy and speech error analyses at the sentence, word, and affix levels, we provide evidence that individual differences in task performance are influenced by the linguistic properties of the material. These findings clarify the role of key language production mechanisms involved in sentence repetition. We propose that it is the versatility to develop a profile across several language production mechanisms that makes sentence repetition particularly useful as a clinical tool.

Choosing a Markov blanket

2020 ◽  
Vol 43 ◽  
Author(s):  
Thomas Parr
Keyword(s):  
Markov Blanket ◽  
Target Article ◽  
The Relationship

Abstract This commentary focuses upon the relationship between two themes in the target article: the ways in which a Markov blanket may be defined and the role of precision and salience in mediating the interactions between what is internal and external to a system. These each rest upon the different perspectives we might take while “choosing” a Markov blanket.

Shall I Move My Right or My Left Hand?

2003 ◽  
Vol 17 (2) ◽  
pp. 69-86 ◽  
Author(s):  
Claudio Babiloni ◽  
Fabio Babiloni ◽  
Filippo Carducci ◽  
Febo Cincotti ◽  
Claudio Del Percio ◽  
...  
Keyword(s):  
Bimanual Coordination ◽  
Central Area ◽  
Eeg Analysis ◽  
Complementary Information ◽  
Left Hand ◽  
Mirror Movements ◽  
Related Potentials ◽  
Motor Acts ◽  
Abstract Event

Abstract Event-related desynchronization/synchronization (ERD/ERS) at alpha (10Hz), beta (20Hz), and gamma (40Hz) bands and movement-related potentials (MRPs) were investigated in right-handed subjects who were “free” to decide the side of unilateral finger movements (“fixed” side as a control). As a novelty, this “multi-modal” EEG analysis was combined with the evaluation of involuntary mirror movements, taken as an index of “bimanual competition.” A main issue was whether the decision regarding the hand to be moved (“free” movements) could modulate ERD/ERS or MRPs overlying sensorimotor cortical areas typically involved in bimanual tasks. Compared to “fixed” movements, “free” movements induced the following effects: (1) more involuntary mirror movements discarded from EEG analysis; (2) stronger vertex MRPs (right motor acts); (3) a positive correlation between these potentials and the number of involuntary mirror movements; (4) gamma ERS over central areas; and (5) preponderance of postmovement beta ERS over left central area (dominant hemisphere). These results suggest that ERD/ERS and MRPs provide complementary information on the cortical processes belonging to a lateralized motor act. In this context, the results on vertex MRPs would indicate a key role of supplementary/cingulate motor areas not only for bimanual coordination but also for the control of “bimanual competition” and involuntary mirror movements.

Könyvismertetések

2007 ◽  
Vol 62 (2) ◽  
pp. 253-265
Author(s):  
István Fekete ◽  
Mária Gósy ◽  
Rozália Eszter Ivády ◽  
Péter Kardos
Keyword(s):  
Second Language ◽  
Second Language Acquisition ◽  
Language Acquisition ◽  
Speech Production ◽  
Perception And Action

DianePecherés RolfA. Zwaan(szerk.): Grounding cognition: The role of perception and action in memory, language, and thinking (Fekete István)     253 CsépeValéria: Az olvasó agy (Gósy Mária) 256 Kormos, Judit: Speech production and second language acquisition (Ivády Rozália Eszter)      260 MarosánGyörgy: Hogyan készül a történelem? (Kardos Péter) 263

scholarly journals Pre-motor versus motor cerebral cortex neuromodulation for chronic neuropathic pain

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Igor Lavrov ◽  
Timur Latypov ◽  
Elvira Mukhametova ◽  
Brian Lundstrom ◽  
Paola Sandroni ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cerebral Cortex ◽  
Motor Cortex ◽  
Initial Assessment ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain ◽  
Long Term Effect ◽  
Stimulation Of

AbstractElectrical stimulation of the cerebral cortex (ESCC) has been used to treat intractable neuropathic pain for nearly two decades, however, no standardized approach for this technique has been developed. In order to optimize targeting and validate the effect of ESCC before placing the permanent grid, we introduced initial assessment with trial stimulation, using a temporary grid of subdural electrodes. In this retrospective study we evaluate the role of electrode location on cerebral cortex in control of neuropathic pain and the role of trial stimulation in target-optimization for ESCC. Location of the temporary grid electrodes and location of permanent electrodes were evaluated in correlation with the long-term efficacy of ESCC. The results of this study demonstrate that the long-term effect of subdural pre-motor cortex stimulation is at least the same or higher compare to effect of subdural motor or combined pre-motor and motor cortex stimulation. These results also demonstrate that the initial trial stimulation helps to optimize permanent electrode positions in relation to the optimal functional target that is critical in cases when brain shift is expected. Proposed methodology and novel results open a new direction for development of neuromodulation techniques to control chronic neuropathic pain.

Role of Cerebral Cortex in Voluntary Movements

1985 ◽  
Vol 65 (5) ◽  
pp. 624-635 ◽  
Author(s):  
Paul D. Cheney
Keyword(s):  
Cerebral Cortex ◽  
Voluntary Movements

scholarly journals Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Hua Yang ◽  
Mengjie Zhang ◽  
Jiahao Shi ◽  
Yunhe Zhou ◽  
Zhipeng Wan ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Mouse Model ◽  
Glutamate Release ◽  
Critical Role ◽  
Conditional Knockout ◽  
Snare Complex ◽  
Extracellular Glutamate ◽  
Glutamate Level

Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explore the possible pathogenetic role of SNAP-25 in schizophrenia. We showed that SNAP-25 conditional knockout (cKO) mice exhibited typical schizophrenia-like phenotype. A significantly elevated extracellular glutamate level was detected in the cerebral cortex of the mouse model. Compared with Ctrls, SNAP-25 was dramatically reduced by about 60% both in cytoplasm and in membrane fractions of cerebral cortex of cKOs, while the other two core members of SNARE complex: Syntaxin-1 (increased ~80%) and Vamp2 (increased ~96%) were significantly increased in cell membrane part. Riluzole, a glutamate release inhibitor, significantly attenuated the locomotor hyperactivity deficits in cKO mice. Our findings provide in vivo functional evidence showing a critical role of SNAP-25 dysfunction on synaptic transmission, which contributes to the developmental of schizophrenia. It is suggested that a SNAP-25 cKO mouse, a valuable model for schizophrenia, could address questions regarding presynaptic alterations that contribute to the etiopathophysiology of SZ and help to consummate the pre- and postsynaptic glutamatergic pathogenesis of the illness.

scholarly journals The future of SIMS: Who embodies which smile and when?

2010 ◽  
Vol 33 (6) ◽  
pp. 464-480 ◽  
Author(s):  
Paula M. Niedenthal ◽  
Martial Mermillod ◽  
Marcus Maringer ◽  
Ursula Hess
Keyword(s):  
Facial Expression ◽  
Eye Contact ◽  
Initial Position ◽  
Top Down ◽  
The Core ◽  
Facial Expression Of Emotion ◽  
Expression Of Emotion ◽  
Target Article ◽  
The Future

AbstractThe set of 30 stimulating commentaries on our target article helps to define the areas of our initial position that should be reiterated or else made clearer and, more importantly, the ways in which moderators of and extensions to the SIMS can be imagined. In our response, we divide the areas of discussion into (1) a clarification of our meaning of “functional,” (2) a consideration of our proposed categories of smiles, (3) a reminder about the role of top-down processes in the interpretation of smile meaning in SIMS, (4) an evaluation of the role of eye contact in the interpretation of facial expression of emotion, and (5) an assessment of the possible moderators of the core SIMS model. We end with an appreciation of the proposed extensions to the model, and note that the future of research on the problem of the smile appears to us to be assured.

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