Equine hair analysis: a non-invasive technique for identifying exposure to drugs and toxins

AbstractHair analysis has been evaluated as a retrospective non-invasive diagnostic technique to identify and quantify drug administration and exposure to mycotoxins and plant toxins in horses. The purpose of this review is to describe and discuss in detail the development and application of this technique to equine hair, and to interpret data generated thus far. Particular attention is paid to both extrinsic and intrinsic factors, including pigmentation and hair growth-rates, that impinge on the conduct of hair analysis and which can be potential sources of error. In the absence of research specific to the horse, this review draws upon comparative data in humans and other species, on hair analysis and potential toxins of particular relevance to the horse.

Download Full-text

Equine hair analysis: a non-invasive technique for identifying exposure to drugs and toxins

Applying Equine Science ◽

10.7313/upo9781904761945.004 ◽

2012 ◽

pp. 29-50

Author(s):

M. Dunnett ◽

S. Tracy ◽

P. Lees

Keyword(s):

Hair Analysis ◽

Invasive Technique ◽

Non Invasive

Download Full-text

The accuracy of non-invasive 3D-CT virtual bronchoscopy technique in comparison with invasive technique

International Journal of Medicine in Developing Countries ◽

10.24911/ijmdc.51-1538516450 ◽

2019 ◽

pp. 1

Author(s):

Basmah Altuwayjiri

Keyword(s):

Invasive Technique ◽

Virtual Bronchoscopy ◽

3D Ct ◽

Non Invasive

Download Full-text

USING DOPPLER TO ASSESS THE FETAL HEALTH FOR THE PREDICTION OF GESTATIONAL OUTCOME

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2014.4_5.1 ◽

2014 ◽

pp. 9-18

Author(s):

Thi Linh Giang Truong ◽

Vu Quoc Huy Nguyen

Keyword(s):

Middle Cerebral Artery ◽

Cerebral Artery ◽

Umbilical Artery ◽

Functional Method ◽

Invasive Technique ◽

Routine Practice ◽

Fetal Health ◽

Uterine Arteries ◽

Non Invasive ◽

Key Words Doppler

Background: Assessment of fetal health plays the most important role in prenatal care because of influence of the prediction of gestational outcome. One of the main aims of routine antenatal care is to identify the ‘ at risk ‘ fetus in order to apply clinical interventions which could results in reduced perinatal morbidity and mortality. Doppler ultrasound is a non invasive technique whereby the movement of blood is studied by detecting the change in frequence of reflected sound, Doppler blood flow velocity waves form of fetal side (umbilical artery, middle cerebral artery ...) and maternal side ( uterine arteries) are discussed and monograms for routine practice are presented. Recently this method is important tool for qualifying high risk pregnancies and help early forecasts the health of the babies and mothers disorder. Doppler sonography in obstetrics is a widely accepted functional method of examining the prediction of gestational outcome. Key words: Doppler, umbilical artery, middle cerebral artery, uterine arteries

Download Full-text

The Anti-Ageing and Whitening Potential of a Cosmetic Serum Containing 3-O-ethyl-l-ascorbic Acid

Life ◽

10.3390/life11050406 ◽

2021 ◽

Vol 11 (5) ◽

pp. 406

Author(s):

Nicola Zerbinati ◽

Sabrina Sommatis ◽

Cristina Maccario ◽

Serena Di Francesco ◽

Maria Chiara Capillo ◽

...

Keyword(s):

Ascorbic Acid ◽

Dermal Fibroblasts ◽

Melanin Content ◽

Dna Protection ◽

Melanin Pigmentation ◽

Intrinsic Factors ◽

Reconstructed Human Epidermis ◽

Solar Ultraviolet ◽

Damage Marker ◽

Extrinsic And Intrinsic Factors

Skin ageing has many manifestations such as wrinkles, dryness, hyperpigmentation, and uneven skin tone. Extrinsic and intrinsic factors, especially solar ultraviolet light (UVB), contribute to skin ageing; its main features are brown spots, alterations in melanin pigmentation, and a decrease in collagen and hyaluronic acid linked to oxidative stress. Several studies showed that topical products containing ingredients with antioxidant activity can reduce oxidative damage; to provide a maximum anti-ageing effect to the skin, topical products can combine various ingredients. C-SHOT SERUM contains a combination of two molecules with a proven anti-ageing activity: a high percentage (30%) of a more stable vitamin C derivative, 3-O-ethyl-l-ascorbic acid, and lactic acid (1%). The product showed a high biocompatibility, assessed through an MTT assay on keratinocytes and on Reconstructed Human Epidermis (RHE, SkinEthic); the anti-ageing activity was demonstrated on human dermal fibroblasts and keratinocytes by a statistically significant increase in collagen production and a reduction of a UVB-induced DNA damage marker (γ-H2AX histone), indicating DNA protection. Moreover, a depigmenting activity, shown by a highly significant decrease in melanin content on treated Reconstructed Human Pigmented Epidermis (RHPE), was assessed. According to the data of our study, the tested product contrasts the effect of skin ageing and irregular pigmentation due to the physiological decline of the skin.

Download Full-text

Non-invasive technique for real-time myocardial infarction detection using faster R-CNN

Multimedia Tools and Applications ◽

10.1007/s11042-021-10957-2 ◽

2021 ◽

Author(s):

H. M. Mohan ◽

P. V. Rao ◽

H. C. Shivaraj Kumara ◽

S. Manasa

Keyword(s):

Myocardial Infarction ◽

Real Time ◽

Invasive Technique ◽

Non Invasive

Download Full-text

Current status of ctDNA in precision oncology for hepatocellular carcinoma

Journal of Experimental & Clinical Cancer Research ◽

10.1186/s13046-021-01940-8 ◽

2021 ◽

Vol 40 (1) ◽

Author(s):

Yan Li ◽

Yuanyuan Zheng ◽

Liwei Wu ◽

Jingjing Li ◽

Jie Ji ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Cancer Progression ◽

Diagnostic Technique ◽

Response Assessment ◽

Selection Response ◽

Circulating Tumor Dna ◽

Current Status ◽

Precision Oncology ◽

Tumor Biopsy ◽

Non Invasive

AbstractThe conventional method used to obtain a tumor biopsy for hepatocellular carcinoma (HCC) is invasive and does not evaluate dynamic cancer progression or assess tumor heterogeneity. It is thus imperative to create a novel non-invasive diagnostic technique for improvement in cancer screening, diagnosis, treatment selection, response assessment, and predicting prognosis for HCC. Circulating tumor DNA (ctDNA) is a non-invasive liquid biopsy method that reveals cancer-specific genetic and epigenetic aberrations. Owing to the development of technology in next-generation sequencing and PCR-based assays, the detection and quantification of ctDNA have greatly improved. In this publication, we provide an overview of current technologies used to detect ctDNA, the ctDNA markers utilized, and recent advances regarding the multiple clinical applications in the field of precision medicine for HCC.

Download Full-text

Thermal Liquid Biopsy (TLB) Focused on Benign and Premalignant Pancreatic Cyst Diagnosis

Journal of Personalized Medicine ◽

10.3390/jpm11010025 ◽

2020 ◽

Vol 11 (1) ◽

pp. 25

Author(s):

Sonia Hermoso-Durán ◽

Guillermo García-Rayado ◽

Laura Ceballos-Laita ◽

Carlos Sostres ◽

Sonia Vega ◽

...

Keyword(s):

Liquid Biopsy ◽

Pancreatic Cyst ◽

Point Of View ◽

Invasive Technique ◽

Background Current ◽

Interesting Point ◽

Pancreatic Lesion ◽

Non Invasive ◽

Patient Diagnosis ◽

New Biomarkers

Background: Current efforts in the identification of new biomarkers are directed towards an accurate differentiation between benign and premalignant cysts. Thermal Liquid Biopsy (TLB) has been previously applied to inflammatory and tumor diseases and could offer an interesting point of view in this type of pathology. Methods: In this work, twenty patients (12 males and 8 females, average ages 62) diagnosed with a pancreatic cyst benign (10) and premalignant (10) cyst lesions were recruited, and biological samples were obtained during the endoscopic ultrasonography procedure. Results: Proteomic content of cyst liquid samples was studied and several common proteins in the different groups were identified. TLB cyst liquid profiles reflected protein content. Also, TLB serum score was able to discriminate between healthy and cysts patients (71% sensitivity and 98% specificity) and between benign and premalignant cysts (75% sensitivity and 67% specificity). Conclusions: TLB analysis of plasmatic serum sample, a quick, simple and non-invasive technique that can be easily implemented, reports valuable information on the observed pancreatic lesion. These preliminary results set the basis for a larger study to refine TLB serum score and move closer to the clinical application of TLB providing useful information to the gastroenterologist during patient diagnosis.

Download Full-text

The economic value and determinants of tourists’ counterfeit purchases: The case of Hong Kong

Tourism Economics ◽

10.1177/1354816619834482 ◽

2019 ◽

Vol 26 (1) ◽

pp. 155-178 ◽

Cited By ~ 3

Author(s):

Stephen Pratt ◽

Christine YH Zeng

Keyword(s):

Hong Kong ◽

Brand Image ◽

Economic Value ◽

Demand Side ◽

Counterfeit Goods ◽

Intrinsic Factors ◽

Extrinsic And Intrinsic Factors

Counterfeiting of fashion brands is a multi-billion dollar industry with an increasing number of goods being counterfeited. This research takes a demand-side approach to measuring counterfeiting activity among tourists in Hong Kong. Non-deceptive counterfeit purchases by tourists in Hong Kong amount to US$761.32 million per year. Tourists’ decision of whether to purchase counterfeit goods depended on a mix of extrinsic and intrinsic factors including psychometric variables, trip-related characteristics, and sociodemographics. Lowering the prices of genuine goods and explaining the risks of purchasing counterfeit goods would be the most effective anti-counterfeit measures. However, lowering the price of genuine goods can diminish the brand image of these luxury items.

Download Full-text