Compulsive and Addictive Sexual Disorders and the Family

CNS Spectrums ◽  
2000 ◽  
Vol 5 (10) ◽  
pp. 53-62 ◽  
Author(s):  
Jennifer P. Schneider
Keyword(s):  
Mental Health ◽  
Family History ◽  
Sexual Behaviors ◽  
Sexual Addiction ◽  
Family Treatment ◽  
Sexual Disorders ◽  
Family Unit ◽  
The Family ◽  
Compulsive Sexual Behaviors ◽  
History Of

AbstractIn the treatment of sexual addiction and compulsivity, the family unit is often neglected. Yet this disorder has a major impact not only on the identified patient, but also on the spouse or partner (the coaddict) and on the family as a whole. Moreover, the family unit is the context in which the sexual addict continues to live, and the mental health of the partner has a significant impact on the sexual addicts recovery. Increasing evidence points to a family history of addiction or dysfunction as a primary contributor to both sexual addiction and coaddiction in adulthood. When compulsive sexual behaviors are present within a family, treatment of both members of the couple improves the couple's relationship as well as the mental health of each partner. In addition, treatment of children in such a family can help break the cycle of sexual addiction and prevent its perpetuation into the next generation.

Kaiser or King?

Tautai ◽  
2017 ◽  
Author(s):  
Patricia O'Brien
Keyword(s):  
New Zealand ◽  
Family History ◽  
World War ◽  
World War One ◽  
Seismic Effects ◽  
Family Unit ◽  
The Family ◽  
History Of ◽  
1918 Influenza ◽  
The Great War

This chapter explores the family history of Ta’isi, the course of his marriage, the birth of his six children to Rosabel and the bringing into his family unit of his first born daughter, Lucy. It tracks the economic rise of Ta’isi as a businessman in the Sāmoan Islands and the prominent role he took to as an interlocutor with German administrators about the running of German Samoa. It then tracks the seismic effects of World War One and its aftermath on Sāmoa. World War One brought an abrupt end to German rule that was replaced by a New Zealand military occupation in 1914. The effects of the Great War were both enormously beneficial to Ta’isi as a businessman, but it also brought the devastating aftermath of the 1918 influenza epidemic that killed over 20% of Samoa’s population, including Ta’isi’s mother, sister, brother, sister-in-law and his beloved only son. This chapter traces these events and their effects on Ta’isi, showing how they led him into an activist role within Sāmoa.

scholarly journals Novel SCN5A p.Val1667Asp Missense Variant Segregation and Characterization in a Family with Severe Brugada Syndrome and Multiple Sudden Deaths

2021 ◽  
Vol 22 (9) ◽  
pp. 4700
Author(s):  
Michelle M. Monasky ◽  
Emanuele Micaglio ◽  
Giuseppe Ciconte ◽  
Ilaria Rivolta ◽  
Valeria Borrelli ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Family History ◽  
Risk Stratification ◽  
Brugada Syndrome ◽  
Electrophysiological Study ◽  
Functional Characterization ◽  
The Family ◽  
Novel Variant ◽  
History Of ◽  
Scn5a Gene

Genetic testing in Brugada syndrome (BrS) is still not considered to be useful for clinical management of patients in the majority of cases, due to the current lack of understanding about the effect of specific variants. Additionally, family history of sudden death is generally not considered useful for arrhythmic risk stratification. We sought to demonstrate the usefulness of genetic testing and family history in diagnosis and risk stratification. The family history was collected for a proband who presented with a personal history of aborted cardiac arrest and in whom a novel variant in the SCN5A gene was found. Living family members underwent ajmaline testing, electrophysiological study, and genetic testing to determine genotype-phenotype segregation, if any. Patch-clamp experiments on transfected human embryonic kidney 293 cells enabled the functional characterization of the SCN5A novel variant in vitro. In this study, we provide crucial human data on the novel heterozygous variant NM_198056.2:c.5000T>A (p.Val1667Asp) in the SCN5A gene, and demonstrate its segregation with a severe form of BrS and multiple sudden deaths. Functional data revealed a loss of function of the protein affected by the variant. These results provide the first disease association with this variant and demonstrate the usefulness of genetic testing for diagnosis and risk stratification in certain patients. This study also demonstrates the usefulness of collecting the family history, which can assist in understanding the severity of the disease in certain situations and confirm the importance of the functional studies to distinguish between pathogenic mutations and harmless genetic variants.

Association between gastric cancer and the family history of gastric cancer

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Hyo Geun Choi ◽  
Wook Chun ◽  
Kuk Hyun Jung
Keyword(s):  
Gastric Cancer ◽  
Family History ◽  
The Family ◽  
History Of

scholarly journals Prostate cancer screening characteristics in men with BRCA1/2 mutations attending a high-risk prevention clinic

2014 ◽  
Vol 8 (11-12) ◽  
pp. 783 ◽  
Author(s):  
Richard Walker ◽  
Alyssa Louis ◽  
Alejandro Berlin ◽  
Sheri Horsburgh ◽  
Robert G. Bristow ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Family History ◽  
High Risk ◽  
Prostate Cancer Screening ◽  
Brca2 Mutation ◽  
Aggressive Disease ◽  
Mutation Carriers ◽  
The Family ◽  
History Of ◽  
Prevention Clinic

Introduction: The prostate-specific antigen (PSA) era and resultant early detection of prostate cancer has presented clinicians with the challenge of distinguishing indolent from aggressive tumours. Mutations in the BRCA1/2 genes have been associated with prostate cancer risk and prognosis. We describe the prostate cancer screening characteristics of BRCA1/2 mutation carriers, who may be classified as genetically-defined high risk, as compared to another high-risk cohort of men with a family history of prostate cancer to evaluate the utility of a targeted screening approach for these men.Methods: We reviewed patient demographics, clinical screening characteristics, pathological features, and treatment outcomes between a group of BRCA1 or BRCA2 mutation carriers and age-matched men with a family history of prostate cancer followed at our institutional Prostate Cancer Prevention Clinic from 1995 to 2012.Results: Screening characteristics were similar between the mutation carriers (n = 53) and the family history group (n = 53). Some cancers would be missed in both groups by using a PSA cut-off of >4 ug/L. While cancer detection was higher in the family history group (21% vs. 15%), the mutation carrier group was more likely to have intermediate- or high-risk disease (88% vs. 36%). BRCA2 mutation carriers were more likely to have aggressive disease, biological recurrence, and distant metastasis.Conclusions: In our cohort, regular screening appears justified for detecting prostate cancer in BRCA1 and BRCA2 carriers and other high-risk populations. Lowering PSA cut-offs and defining monitoring of PSA velocity as part of the screening protocol may be useful. BRCA2 is associated with more aggressive disease, while the outcome for BRCA1 mutation carriers requires further study. Large multinational studies will be important to define screening techniques for this unique high-risk population.

HEREDITARY AND ENVIRONMENTAL FACTORS IN THE PATHOGENESIS OF RHEUMATIC FEVER

PEDIATRICS ◽  
1957 ◽  
Vol 19 (5) ◽  
pp. 908-915
Author(s):  
Eugene F. Diamond
Keyword(s):  
Family History ◽  
Rheumatic Fever ◽  
Autosomal Recessive ◽  
Positive Family History ◽  
Recessive Gene ◽  
Environmental Groups ◽  
Environmental Group ◽  
The Family ◽  
History Of ◽  
Unfavorable Environmental Factor

A study of cases of rheumatic fever admitted to La Rabida Sanitarium over a 5-year period was carried out to evaluate heredity and environment as etiologic factors in rheumatic disease. The incidence of rheumatic fever was shown to be higher in families where one or both parents were known to have a positive family history of rheumatic fever. The incidence of rheumatic fever was compared in environmental groups. A totally unfavorable environment was shown to increase the incidence of rheumatic fever. No single unfavorable environmental factor changed the incidence of rheumatic fever. The incidence of rheumatic fever in each environmental group was higher when there was a positive family history for rheumatic fever, indicating an hereditary factor in the family incidence of rheumatic fever. Analysis of the various mating types in the families with a positive rheumatic trait was carried out. Agreement with a simple autosomal recessive gene inheritance was obtained in families where both parents had a definite family history, but no agreement was obtained in cases where only one parent gave a positive family history.

A Sax Is Born

2019 ◽  
pp. 3-10
Author(s):  
Con Chapman
Keyword(s):  
Family History ◽  
Birth Certificate ◽  
The South ◽  
The Family ◽  
History Of

This chapter provides data regarding Cornelius Hodges’s birth and traces his family history to his grandparents’ generation. Confusion as to the exact spelling of his last name (“Hodges,” not “Hodge”) is resolved by reference to his birth certificate. Census records reveal that, contrary to prior accounts of his life, he had not one sister but three, all older. The change in his name from “Cornelius” to “Johnny” is discussed, along with the seven nicknames that he was given by colleagues. The chapter also details the history of the Cambridge, Massachusetts, neighborhood where he was born—Cambridgeport—and of the South End of Boston, to which the family would move when he was twelve, after a stop in North Cambridge that has been overlooked in prior accounts of his life.

Plot and Theme in the Book of Ruth

2018 ◽  
Author(s):  
J. Andrew Dearman
Keyword(s):  
Family History ◽  
Short Story ◽  
Narrative Analysis ◽  
National History ◽  
The Family ◽  
History Of ◽  
The Town

This chapter explores plot and theme in the book of Ruth as an example of narrative analysis. The book is identified as a short story with a dilemma facing the family of Elimelech from the town of Bethlehem and the tribe of Judah. The family history of Elimelech and the role of the Moabite Ruth in it are examined first as a self-contained narrative and then in the context of Israel’s national history. The family dilemma is resolved with the birth of an heir for the family of Elimelech and the contribution of the family to the tribe of Judah to Israel’s national storyline is further revealed in the kingship of David, a descendant of Elimelech and Ruth.

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