Macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Results from the Australian Longitudinal Study on Women's Health

AbstractObjectiveTo investigate the association between macronutrient intake and type 2 diabetes risk in middle-aged Australian women.DesignA prospective cohort study, with 6 years (2002–2007) of follow up. Dietary intake was assessed with a validated FFQ. Relative risks with 95 % confidence intervals were used to examine risk associations.SettingAustralian Longitudinal Study on Women's Health, Australia.SubjectsAustralian women (n 8370) from the Australian Longitudinal Study on Women's Health aged 45–50 years and free of type 2 diabetes at baseline.ResultsAfter 6 years of follow-up, 311 women developed type 2 diabetes. After adjusting for sociodemographic, lifestyle and other dietary risk factors, MUFA, total n-3 PUFA, α-linolenic acid and total n-6 PUFA intakes were positively associated with the incidence of type 2 diabetes. The relative risks for type 2 diabetes for the highest compared with the lowest quintiles were 1·64 (95 % CI 1·06, 2·54), P = 0·04 for MUFA; 1·55 (95 % CI 1·03, 2·32), P = 0·01 for n-3 PUFA; 1·84 (95 % CI 1·25, 2·71), P < 0·01 for α-linolenic acid; and 1·60 (95 % CI 1·03, 2·48), P = 0·04 for n-6 PUFA. Other dietary macronutrients were not significantly associated with diabetes risk.ConclusionsThe data indicate that consumption of MUFA, n-3 PUFA and n-6 PUFA may influence the risk of developing type 2 diabetes in women.

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Diet quality score is a predictor of type 2 diabetes risk in women: The Australian Longitudinal Study on Women's Health

British Journal Of Nutrition ◽

10.1017/s0007114514001688 ◽

2014 ◽

Vol 112 (6) ◽

pp. 945-951 ◽

Cited By ~ 15

Author(s):

Amani Alhazmi ◽

Elizabeth Stojanovski ◽

Mark McEvoy ◽

Wendy Brown ◽

Manohar L. Garg

Keyword(s):

Type 2 Diabetes ◽

Longitudinal Study ◽

Women’S Health ◽

Women's Health ◽

Diet Quality ◽

Diabetes Risk ◽

Dietary Guidelines ◽

Australian Longitudinal Study ◽

Incident Cases

The present study aimed to determine the ability of two diet quality scores to predict the incidence of type 2 diabetes in women. The study population comprised a nationally representative sample of 8370 Australian middle-aged (45–50 years) women participating in the ALSWH (Australian Longitudinal Study on Women's Health), who were free of diabetes and completed FFQ at baseline. The associations between the Australian Recommended Food Score (ARFS) and Dietary Guideline Index (DGI) with type 2 diabetes risk were assessed using multiple logistic regression models, adjusting for sociodemographic characteristics, lifestyle factors and energy intake. During 6 years of follow-up, 311 incident cases of type 2 diabetes were reported. The DGI score was inversely associated with type 2 diabetes risk (OR comparing the highest with the lowest quintile of DGI was 0·51; 95 % CI 0·35, 0·76; P for trend = 0·01). There was no statistically significant association between the ARFS and type 2 diabetes risk (OR comparing the highest with the lowest quintile of ARFS was 0·99; 95 % CI 0·68, 1·43; P for trend = 0·42). The results of the present prospective study indicate that the DGI score, which assesses compliance with established dietary guidelines, is predictive of type 2 diabetes risk in Australian women. The risk of type 2 diabetes among women in the highest quintile of DGI was approximately 50 % lower than that in women in the lowest quintile. The ARFS was not significantly predictive of type 2 diabetes.

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