scholarly journals Serum and red-blood-cell folate demonstrate differential associations with BMI in pregnant women

2016 ◽  
Vol 19 (14) ◽  
pp. 2572-2579 ◽  
Author(s):  
Minxue Shen ◽  
Shazia Hira Chaudhry ◽  
Amanda J MacFarlane ◽  
Laura Gaudet ◽  
Graeme N Smith ◽  
...  
Keyword(s):  
Folic Acid ◽  
Pregnant Women ◽  
Maternal Education ◽  
Folic Acid Supplementation ◽  
Differential Association ◽  
Serum Folate ◽  
Obese Women ◽  
Sample Collection ◽  
Cross Sectional ◽  
Acid Supplementation

AbstractObjectiveTo examine the association between BMI and folate concentrations in serum and red blood cells (RBC) in pregnant women.DesignA cross-sectional comparison of folate concentrations in serum and RBC sampled simultaneously from the same individual.SettingThe Ottawa Hospital and Kingston General Hospital, Ontario, Canada.SubjectsPregnant women recruited between 12 and 20 weeks of gestation.ResultsA total of 869 pregnant women recruited from April 2008 to April 2009 were included in the final analysis. Serum folate was inversely associated and RBC folate positively associated with BMI, after adjusting for folic acid supplementation, age, gestational age at blood sample collection, race, maternal education, annual income, smoking and MTHFR 677C→T genotype. In stratified analyses, this differential association was significant in women with the MTHFR CC variant. In women with the CT and TT variants, the differential associations were in the same direction but not significant. Folic acid supplementation during pregnancy did not alter the differential association of BMI with serum and RBC folate concentration. This indicates that the current RBC folate cut-off approach for assessing risk of neural tube defects in obese women may be limited.ConclusionsBMI is inversely associated with serum folate and positively associated with RBC folate in pregnant women, especially for those with the MTHFR CC variant.

scholarly journals Adherence rate to iron folic acid supplementation among pregnant women

2019 ◽  
Author(s):  
Wondwossen Niguse
Keyword(s):  
Folic Acid ◽  
Data Collection ◽  
Pregnant Women ◽  
Maternal Education ◽  
Folic Acid Supplementation ◽  
Adherence Rate ◽  
Antenatal Visit ◽  
Acid Supplementation ◽  
Iron Folic Acid Supplementation ◽  
Iron Folic Acid

AbstractIntroductionGlobally 41.8% of pregnant women are anemic with the highest proportion affected in developing countries. Nationally, only 0.4% of the pregnant women take Iron supplements more than 90 days of the recommended 180 days. In Oromiya region 75.3% of pregnant women do not take any iron tablets or syrup during their last pregnancy, while 10.8% take for less than 60 days, 0.4% took for 60-89 days and only 0.3% took for 90 days or more.ObjectiveTo assess the adherence rate to iron and folic acid supplements among pregnant women attending antenatal clinics in Asella Town, south east EthiopiaMethod and materialsInstitution based cross-sectional quantitative study design was conducted in Asella town from September 2015 to June 2016. A purposive sampling technique used to select the health institution. There are six health institutions selected for this study. The sample size 317 was selected with systematic random sampling method. Ten percent of pre-test was conducted in one institution which is not included in data collection. Data were collected using structured pre-tested questionnaire. Before data collection verbal consent was obtained. The collected data were analyzed using Epi-data and SPSS version 22.00 packages.ResultThe study revealed that Out of 317 pregnant women 296 (93%) responded to the questioner. The study revealed that 177 (59.8%) of pregnant mothers in the town adhered to the iron/folic acid supplement.Conclusion and recommendationAdherence of iron/folic acid supplementation found in this study is very low. Consequently, maternal education, adequate supplement supply to the health facility, early starting antenatal visit, and health education on duration of supplementation

scholarly journals Counselling and knowledge on iron and folic acid supplementation (IFAS) among pregnant women in Kiambu County, Kenya: a cross-sectional study

2019 ◽  
Vol 1 ◽  
pp. 21
Author(s):  
Mary Kamau ◽  
Samuel Kimani ◽  
Waithira Mirie
Keyword(s):  
Folic Acid ◽  
Pregnant Women ◽  
Community Education ◽  
Folic Acid Supplementation ◽  
Cross Sectional Study ◽  
Health Facilities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Acid Supplementation ◽  
Iron And Folic Acid

Background: The increased demand for iron and folic acid during pregnancy is not met through diet due to insufficiency or reduced bioavailability of nutrients among women from low income countries. Thus, iron and folic acid supplementation (IFAS) is a promising interventional strategy for control of anaemia during pregnancy. Kenya adopted the global IFAS intervention with a target of 80% coverage by 2017, however, the compliance remains low. Increasing awareness, counselling, communication and community education on IFAS have improved compliance among pregnant women. Thus, we aimed to determine: IFAS knowledge, availability, practices, and content of IFAS counselling among pregnant women attending health facilities in Kiambu County, Kenya. Methods: A cross-sectional study involving 364 pregnant women aged 15-49 years. A two stage cluster sampling, including one sub-county and five public health facilities were used. A pre-tested structured questionnaire consisting of socio-demographic data, maternal knowledge and counselling on IFAS was used. An observation checklist was used to observe practices and content of antenatal counselling session in each facility. Data was analysed using STATA in which descriptive and inferential statistics were computed. Results: Of 364 respondents, less than half (40.9%) scored high on knowledge on IFAS. Women who were counselled on duration of IFAS intake, side effects, and their mitigation were more likely (p <0.005) to have high IFAS knowledge. Although all the health facilities had varied IFAS posters displayed, none had key IFAS counselling documents. Conclusion: Less than half of the pregnant women had high IFAS knowledge, IFAS documents were scarce in health facilities, IFAS counselling information in different health facilities was limited and varied and content of counselling was associated with levels of knowledge on IFAS. This underscores the need to strengthen focused and targeted IFAS counselling for pregnant women and standardization of counselling messages to improve compliance and pregnancy outcomes.

scholarly journals Knowledge and Compliance of Iron and Folic Acid Supplementation among Pregnant & Postnatal Women in a Hospital of Kathmandu

2020 ◽  
Vol 7 (1) ◽  
pp. 63-69
Author(s):  
Rupesh Kumar Mishra ◽  
Kalpana Tiwari
Keyword(s):  
Folic Acid ◽  
Pregnant Women ◽  
Compliance Rate ◽  
Folic Acid Supplementation ◽  
Deficiency Anemia ◽  
Cross Sectional ◽  
Acid Supplementation ◽  
Postnatal Women ◽  
Level Of Knowledge ◽  
Iron And Folic Acid

The high prevalence of iron deficiency anemia and low compliance of iron and folic acid supplementation was reported among pregnant women in Nepal. This study aimed to determine the knowledge and compliance of iron and folic acid supplementation among pregnant and postnatal women in Kathmandu. A descriptive cross-sectional study design was adopted for the study. Sample size was 103 and purposive sampling technique was used to collect the data. All Pregnant women of having above 7 month pregnancy and postnatal’s up to 6 months women were included. Data was collected by using self-administered questionnaire .All the obtained data were analyzed with the help of SPSS version 20. Assessment of knowledge revealed that 85.6 % (88) of the participants have adequate knowledge regarding iron and folic acid supplementation .The findings showed 78.6% (81) of the respondents had  iron and folic acid compliance as standard of Nepal government that is to be taken minimum 180 tablet before delivery. It concludes that the level of knowledge and compliance rate of iron and folic acid supplementation in Kathmandu is satisfactory in comparisons to national status i.e. 42% according to Nepal Demographic health survey 2016. Pearson chi-square test shows that level of knowledge on iron and folic acid tablet is not associated with the compliance of iron and folic acid tablet (χ²= 0.019, p< 0.889). The main reason of respondents having compliance is due to having proper counseling from health worker and non compliance is due to forgetting to have tablet. Therefore improving knowledge level only can’t improve compliance level, various factors like counseling, accessibility and availability of iron and folic acid tablet, side effect of tablet and family support also affects the compliance of iron and folic acid supplementation.

Obesity is associated with folate metabolism

2020 ◽  
Vol 90 (3-4) ◽  
pp. 353-364 ◽  
Author(s):  
Süleyman Köse ◽  
Saniye Sözlü ◽  
Hatice Bölükbaşi ◽  
Nüket Ünsal ◽  
Makbule Gezmen-Karadağ
Keyword(s):  
Folic Acid ◽  
Folic Acid Supplementation ◽  
Normal Weight ◽  
Folate Intake ◽  
Serum Folate ◽  
Systemic Review ◽  
Lower Serum ◽  
Cross Sectional ◽  
Acid Supplementation ◽  
Supplement Use

Abstract. Objective: The aim of the present study is to perform a systemic review of the previous studies executed on the association between obesity and folate. Method: In the present research, the selected keywords were scanned on the PubMed, Web of Science, Cochrane and Lilac databases between May and June, 2017 through Gazi University’s network. In total, 4236 clinical, randomized controlled, cross-sectional and prospective studies were determined and 17 of these that specifically fit the aims of the present research were reviewed. This study involved an electronic literature search of databases on folic acid and obesity published in the English language between 2000 and 2016. Results: Of the 17 studies, 5 were based on folic acid supplementation and 12 were related with participants’ folate status. As a general consequence of both intake and serum/status measurements of folic acid supplementation: It was found that obesity-associated metabolic changes might affect individual folate use and obese individuals had lower serum folate levels, although there was no change in folate intake. Conclusion: Overweight and obese individuals have lower serum folate concentrations when compared with individuals with normal weight. It is explained by increased use of folic acid, urinary excretion, dilution of blood volume, different levels in different tissues and changes in the endocrine functions of folate. Individuals with higher Body Mass Indexes have less supplement use, unhealthier diets and donot consume sufficient vegetables and fruits, all of which can affect decrease in folate levels. Furthermore, adiposity may affect folate absorption by intestinal epithelium.

scholarly journals Maternal Knowledge Associated with the Prevalence of Iron and Folic Acid Supplementation Among Pregnant Women in Muntinlupa, Philippines: A Cross-Sectional Study

2021 ◽  
Vol Volume 15 ◽  
pp. 501-510
Author(s):  
Tadashi Yamashita ◽  
Ramon Emilio Daniel Roces ◽  
Cecilia Ladines-Llave ◽  
Maria Teresa Reyes Tuliao ◽  
Mary Wanjira Kamau ◽  
...  
Keyword(s):  
Folic Acid ◽  
Pregnant Women ◽  
Folic Acid Supplementation ◽  
Cross Sectional Study ◽  
Maternal Knowledge ◽  
Sectional Study ◽  
Cross Sectional ◽  
Acid Supplementation ◽  
Iron And Folic Acid

scholarly journals Counselling and knowledge on iron and folic acid supplementation (IFAS) among pregnant women in Kiambu County, Kenya: a cross-sectional study

2019 ◽  
Vol 1 ◽  
pp. 21
Author(s):  
Mary Kamau ◽  
Samuel Kimani ◽  
Waithira Mirie
Keyword(s):  
Folic Acid ◽  
Pregnant Women ◽  
Community Education ◽  
Folic Acid Supplementation ◽  
Cross Sectional Study ◽  
Health Facilities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Acid Supplementation ◽  
Iron And Folic Acid

Background: The increased demand for iron and folic acid during pregnancy is not met through diet due to insufficiency or reduced bioavailability of nutrients among women from low income countries. Thus, iron and folic acid supplementation (IFAS) is a promising interventional strategy for control of anaemia during pregnancy. Kenya adopted the global IFAS intervention with a target of 80% coverage by 2017, however, the compliance remains low. Increasing awareness, counselling, communication and community education on IFAS have improved compliance among pregnant women. Thus, we aimed to determine: IFAS knowledge, availability, practices, and content of IFAS counselling among pregnant women attending health facilities in Kiambu County, Kenya. Methods: A cross-sectional study involving 364 pregnant women aged 15-49 years. A two stage cluster sampling, including one sub-county and five public health facilities were used. A pre-tested, structured questionnaire consisting of socio-demographic data, maternal knowledge and counselling on IFAS was used. An observation checklist was used to observe practices and content of antenatal counselling session in each facility. Data was analysed using STATA in which descriptive and inferential statistics were computed. Results: Of 364 respondents, less than half (40.9%) scored high on knowledge on IFAS. Women who were counselled on duration of IFAS intake, side effects, and their mitigation were more likely (p <0.005) to have high IFAS knowledge. Although all the health facilities had varied IFAS posters displayed, none had key IFAS counselling documents. Conclusion: Less than half of the pregnant women had high IFAS knowledge, IFAS documents were scarce in health facilities, IFAS counselling information in different health facilities was limited and varied, and content of counselling was associated with levels of knowledge on IFAS. This underscores the need to strengthen focused and targeted IFAS counselling for pregnant women and standardization of counselling messages to improve compliance and pregnancy outcomes.

scholarly journals Counselling on iron and folic acid supplementation (IFAS) is associated with improved knowledge among pregnant women in a rural county of Kenya: a cross-sectional study

2018 ◽  
Vol 1 ◽  
pp. 21
Author(s):  
Mary Kamau ◽  
Samuel Kimani ◽  
Waithira Mirie
Keyword(s):  
Folic Acid ◽  
Side Effects ◽  
Pregnant Women ◽  
Folic Acid Supplementation ◽  
Cross Sectional Study ◽  
Health Facilities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Acid Supplementation ◽  
Iron And Folic Acid

Background: The demand for iron and folic acid, is greatly increased during pregnancy. The high demand is not met through diet due to insufficiency or reduced bioavailability of nutrients among women from low income countries. Thus, iron and folic acid supplementation (IFAS) is a promising interventional strategy for control of anaemia during pregnancy. Kenya adopted the global IFAS intervention with a target of 80% coverage by 2017, however, the compliance remains low. Increasing awareness, counselling, communication and community education on IFAS have improved compliance among pregnant women. Thus, we aimed to determine: availability, practices, and content of IFAS counselling on knowledge of antenatal mothers attending health facilities in Kiambu County, Kenya. Methods: A cross-sectional study involving 364 pregnant women aged 15-49 years attending antenatal clinic. A two stage cluster sampling, including one sub-county and five public primary health facilities were used. A pre-tested structured questionnaire consisting of socio-demographic data, maternal knowledge and counselling on IFAS was used. An observation checklist was used to observe practices and content of antenatal counselling session in each facility. Data was analysed using STATA in which descriptive and inferential statistics were computed. Results: Of 364 respondents, less than half (40.9%) scored high on knowledge on IFAS. Women who were counselled on duration of IFAS intake, side effects, and their mitigation were more likely (p <0.005) to have high IFAS knowledge. Although all the health facilities had varied IFAS posters displayed, none had key IFAS counselling documents. Conclusion: Content of counselling substantially contributed to high level of knowledge on IFAS among pregnant women. Counselling information on the duration of IFAS supplementation, IFAS side effects, and their management are the predictors of IFAS knowledge among pregnant women. This underscores the need to strengthen focused and targeted IFAS counselling for pregnant women to improve compliance and pregnancy outcomes.

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