scholarly journals Trends in the incidence and DALYs of schizophrenia at the global, regional and national levels: results from the Global Burden of Disease Study 2017

2020 ◽  
Vol 29 ◽  
Author(s):  
Hairong He ◽  
Qingqing Liu ◽  
Ning Li ◽  
Liyang Guo ◽  
Fengjie Gao ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Health Care Systems ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Uncertainty Interval ◽  
Systematic Analysis ◽  
Life Years ◽  
Disease Study ◽  
Incident Cases

Abstract Aim Schizophrenia is a serious health problem worldwide. This systematic analysis aims to quantify the burden of schizophrenia at the global, regional and national levels using the Global Burden of Disease Study 2017 (GBD 2017). Methods We collected detailed information on the number of incidence cases, disability-adjusted life years (DALYs) and age-standardised incidence rate (ASIR) and age-standardised rate of DALYs (ASDR) during 1990–2017 from GBD 2017. The estimated annual percentage changes (EAPCs) in the ASIR and in the ASDR were calculated to quantify the temporal trends in the ASIR and ASDR of schizophrenia. Results Globally there were 1.13 million (95% uncertainty interval [UI] = 1.00 to 1.28) incident schizophrenia cases and 12.66 million (95% UI = 9.48 to 15.56) DALYs due to schizophrenia in 2017. The global ASIR decreased slightly from 1990 to 2017 (EAPC = −0.124, 95% UI = −0.114 to −0.135), while the ASDR was stable. The number of incident cases, DALYs, ASIR and ASDR were higher for males than for females. The incident rate and DALYs rate were highest among those aged 20–29 and 30–54 years, respectively. ASIR and ASDR were highest in East Asia in 2017, at 19.66 (95% UI = 17.72 to 22.00) and 205.23 (95% UI = 153.13 to 253.34), respectively. In 2017, the ASIR was highest in countries with a high-moderate sociodemographic index (SDI) and the ASDR was highest in high-SDI countries. We also found that the EAPC in ASDR was negatively correlated with the ASDR in 1990 (P = 0.001, ρ = −0.23). Conclusion The global burden of schizophrenia remains large and continues to increase, thereby increasing the burden on health-care systems. The reported findings should be useful for resource allocation and health services planning for the increasing numbers of patients with schizophrenia in ageing societies.

scholarly journals Global, Regional, and National Burden of Myocarditis From 1990 to 2017: A Systematic Analysis Based on the Global Burden of Disease Study 2017

2021 ◽  
Vol 8 ◽  
Author(s):  
Xiqiang Wang ◽  
Xiang Bu ◽  
Linyan Wei ◽  
Jing Liu ◽  
Dandan Yang ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Uncertainty Interval ◽  
Systematic Analysis ◽  
Burden Distribution ◽  
The Past ◽  
Life Years ◽  
Global Age ◽  
Disease Study

Objective: The global trends in myocarditis burden over the past two decades remain poorly understood and might be increasing during the coronavirus disease 2019 (COVID-19) worldwide pandemic. This study aimed to provide comprehensive estimates of the incidence, mortality, and disability-adjusted life years (DALYs) for myocarditis globally from 1990 to 2017.Methods: Data regarding the incidence, mortality, DALY, and estimated annual percentage change (EAPC) between 1990 and 2017 for myocarditis worldwide were collected and calculated from the 2017 Global Burden of Disease study. We additionally calculated the myocarditis burden distribution based on the Socio-Demographic Index (SDI) quintile and Human Development Index (HDI).Results: The incidence cases of myocarditis in 2017 was 3,071,000, with a 59.6% increase from 1990, while the age-standardized incidence rate (ASIR) was slightly decreased. The number of deaths due to myocarditis increased gradually from 27,120 in 1990 to 46,490 in 2017. The middle SDI quintile showed the highest number of myocarditis-related deaths. On the contrary, the global age-standardized death rate (ASDR) decreased with an overall EAPC of −1.4 [95% uncertainty interval (UI) = −1.8 to −1.0]. Similar to ASDR, the global age-standardized DALY rate also declined, with an EAPC of −1.50 (95% UI = −2.30 to −0.8) from 1990 to 2017. However, there was a 12.1% increase in the number of DALYs in the past 28 years; the middle SDI and low-middle SDI quintiles contributed the most to the DALY number in 2017. We also observed significant positive correlations between the EPAC of age-standardized rate and HDI for both death and DALY in 2017.Conclusions: Globally, the ASIR, ASDR, and age-standardized DALY rate of myocarditis decreased slightly from 1990 to 2017. The middle SDI quintile had the highest level of ASIR, ASDR, and age-standardized DALY rate, indicating that targeted control should be developed to reduce the myocarditis burden especially based on the regional socioeconomic status. Our findings also provide a platform for further investigation into the myocarditis burden in the era of COVID-19.

scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Burden Of Disease ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Public Health Issue ◽  
Global Burden ◽  
Common Chronic Disease ◽  
Incidence Trends ◽  
Disease Study ◽  
Incident Cases

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASR trends also varied considerably by regions and countries. The increase in ASR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88).Conclusions: Both the number of incident cases and ASR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

scholarly journals Unintentional injuries in Mexico, 1990–2017: findings from the Global Burden of Disease Study 2017

2020 ◽  
Vol 26 (Supp 1) ◽  
pp. i154-i161
Author(s):  
Martha Híjar ◽  
Ricardo Pérez-Núñez ◽  
Elisa Hidalgo-Solórzano ◽  
Bernardo Hernández Prado ◽  
Rosario Valdez-Santiago ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Unintentional Injury ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Unintentional Injuries ◽  
Targeted Interventions ◽  
Life Years ◽  
Injury Burden ◽  
Disease Study ◽  
Incident Cases

BackgroundTo date, the burden of injury in Mexico has not been comprehensively assessed using recent advances in population health research, including those in the Global Burden of Disease Study 2017 (GBD 2017).MethodsWe used GBD 2017 for burden of unintentional injury estimates, including transport injuries, for Mexico and each state in Mexico from 1990 to 2017. We examined subnational variation, age patterns, sex differences and time trends for all injury burden metrics.ResultsUnintentional injury deaths in Mexico decreased from 45 363 deaths (44 662 to 46 038) in 1990 to 42 702 (41 439 to 43 745) in 2017, while age-standardised mortality rates decreased from 65.2 (64.4 to 66.1) in 1990 to 35.1 (34.1 to 36.0) per 100 000 in 2017. In terms of non-fatal outcomes, there were 3 120 211 (2 879 993 to 3 377 945) new injury cases in 1990, which increased to 5 234 214 (4 812 615 to 5 701 669) new cases of injury in 2017. We estimated 2 761 957 (2 676 267 to 2 859 777) disability-adjusted life years (DALYs) due to injuries in Mexico in 1990 compared with 2 376 952 (2 224 588 to 2 551 004) DALYs in 2017. We found subnational variation in health loss across Mexico’s states, including concentrated burden in Tabasco, Chihuahua and Zacatecas.ConclusionsIn Mexico, from 1990 to 2017, mortality due to unintentional injuries has decreased, while non-fatal incident cases have increased. However, unintentional injuries continue to cause considerable mortality and morbidity, with patterns that vary by state, age, sex and year. Future research should focus on targeted interventions to decrease injury burden in high-risk populations.

scholarly journals Burden of Eating Disorders in China, 1990-2019: An Updated Systematic Analysis of the Global Burden of Disease Study 2019

2021 ◽  
Vol 12 ◽  
Author(s):  
Zhitao Li ◽  
Lili Wang ◽  
Haixia Guan ◽  
Cheng Han ◽  
Peng Cui ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Burden Of Disease ◽  
National Level ◽  
Epidemiological Data ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Systematic Analysis ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study

Background: Eating disorders, including anorexia nervosa (AN) and bulimia nervosa (BN), are complex mental disorders. A better understanding of the burden of eating disorders is essential for improving their management. Information about the burden of eating disorders at the national level in China remains unclear.Methods: This is a systematic analysis of the Global Burden of Disease Study (GBD) 2019. The sex- and age-specific prevalence, incidence, and disability-adjusted life years (DALYs) of eating disorders in China were estimated by systematically reviewing all available epidemiological data and inputting these data into a Bayesian meta-regression tool (DisMod-MR 2.0). Trends in the age-standardized prevalence, incidence, and DALYs due to AN and BN were assessed from 1990 to 2019.Results: The age-standardized incidence rate (ASIR), prevalence rate (ASPR), and DALY rate per 100,000 population were estimated to be 13.22 (95% UI, 9.35–18.23), 38.08 (95% UI: 26.37–55.73), and 8.38 (95% UI, 4.87–13.35) for AN and 130.05 (95% UI, 84.02–187.13), 75.21 (95% UI, 48.52–105.97), and 16.16 (95% UI, 9.23–25.40) for BN, respectively, in 2019. The prevalence, incidence, and DALY rate of AN peaked at 15–19 years old. The prevalence and DALY rate of BN peaked at 30–34 years old. Females had a higher burden of AN and a lower burden of BN than males. The ASIR, ASPR, and DALY significantly increased by 1.3% (95% CI: 1.3–1.4%), 1.6% (95% CI, 1.5–1.6%), and 1.6% (95% CI, 1.5–1.7%) for AN and 1.4% (95% CI: 1.4–1.4%), 2.0% (95% CI, 2.0–2.1%), and 2.0% (95% CI, 2.0–2.1%) for BN, respectively, from 1990 to 2019 in China. In addition, the increments in all the age-standardized measures of BN were higher in males than in females.Conclusions: The burden of eating disorders in China showed unexpected patterns that varied by sex and age, with increasing trends of AN and BN from 1990 to 2019. More attention should be given to improving the burden of BN in males in China.

scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Burden Of Disease ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Public Health Issue ◽  
Global Burden ◽  
Common Chronic Disease ◽  
Incidence Trends ◽  
Disease Study ◽  
Incident Cases

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASIR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASIR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASIRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASIR trends also varied considerably by regions and countries. The increase in ASIR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88).Conclusions: Both the number of incident cases and ASIR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Burden Of Disease ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Public Health Issue ◽  
Global Burden ◽  
Common Chronic Disease ◽  
Incidence Trends ◽  
Disease Study ◽  
Incident Cases

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASR trends also varied considerably by regions and countries. The increase in ASR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88). Conclusions: Both the number of incident cases and ASR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

scholarly journals Global, regional, and national burden of neck pain in the general population, 1990-2017: systematic analysis of the Global Burden of Disease Study 2017

BMJ ◽  
2020 ◽  
pp. m791 ◽  
Author(s):  
Saeid Safiri ◽  
Ali-Asghar Kolahi ◽  
Damian Hoy ◽  
Rachelle Buchbinder ◽  
Mohammad Ali Mansournia ◽  
...  
Keyword(s):  
General Population ◽  
Neck Pain ◽  
Burden Of Disease ◽  
Point Prevalence ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Uncertainty Interval ◽  
Systematic Analysis ◽  
Disease Study ◽  
Years Lived With Disability

Abstract Objective To use data from the Global Burden of Disease Study between 1990 and 2017 to report the rates and trends of point prevalence, annual incidence, and years lived with disability for neck pain in the general population of 195 countries. Design Systematic analysis. Data source Global Burden of Diseases, Injuries, and Risk Factors Study 2017. Main outcome measures Numbers and age standardised rates per 100 000 population of neck pain point prevalence, annual incidence, and years lived with disability were compared across regions and countries by age, sex, and sociodemographic index. Estimates were reported with uncertainty intervals. Results Globally in 2017 the age standardised rates for point prevalence of neck pain per 100 000 population was 3551.1 (95% uncertainty interval 3139.5 to 3977.9), for incidence of neck pain per 100 000 population was 806.6 (713.7 to 912.5), and for years lived with disability from neck pain per 100 000 population was 352.0 (245.6 to 493.3). These estimates did not change significantly between 1990 and 2017. The global point prevalence of neck pain in 2017 was higher in females compared with males, although this was not significant at the 0.05 level. Prevalence increased with age up to 70-74 years and then decreased. Norway (6151.2 (95% uncertainty interval 5382.3 to 6959.8)), Finland (5750.3 (5058.4 to 6518.3)), and Denmark (5316 (4674 to 6030.1)) had the three highest age standardised point prevalence estimates in 2017. The largest increases in age standardised point prevalence estimates from 1990 to 2017 were in the United Kingdom (14.6% (10.6% to 18.8%)), Sweden (10.4% (6.0% to 15.4%)), and Kuwait (2.6% (2.0% to 3.2%)). In general, positive associations, but with fluctuations, were found between age standardised years lived with disability for neck pain and sociodemographic index at the global level and for all Global Burden of Disease regions, suggesting the burden is higher at higher sociodemographic indices. Conclusions Neck pain is a serious public health problem in the general population, with the highest burden in Norway, Finland, and Denmark. Increasing population awareness about risk factors and preventive strategies for neck pain is warranted to reduce the future burden of this condition.

scholarly journals The burden of cardiovascular diseases in Ethiopia from 1990 to 2017: evidence from the Global Burden of Disease Study

2020 ◽  
Author(s):  
Solomon Ali ◽  
Awoke Misganaw ◽  
Asnake Worku ◽  
Zelalem Destaw ◽  
Legesse Negash ◽  
...  
Keyword(s):  
Heart Disease ◽  
Cardiovascular Diseases ◽  
Burden Of Disease ◽  
Public Health Problem ◽  
Study Data ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Uncertainty Interval ◽  
Systematic Analysis ◽  
Life Years

Abstract In Ethiopia, evidence on the national burden of cardiovascular diseases (CVDs) is limited. To address this gap, this systematic analysis estimated the burden of CVDs in Ethiopia using the Global Burden of Disease (GBD) 2017 study data. The age-standardized CVD prevalence, disability-adjusted life years (DALYs) and mortality rates in Ethiopia were 5534 (95% uncertainty interval [UI] 5310.09 - 5774.0), 3549.6 (95% UI 3229.0 - 3911.9) and 182.63 (95% UI 165.49 - 203.9) per 100 000 population, respectively. Compared with 1990, the age-standardized CVD prevalence rate in 2017 showed no change. But significant reductions were observed in CVD mortality (54.7%), CVD DALYs (57.7%) and all-cause mortality (53.4%). The top three prevalent CVDs were ischaemic heart disease, rheumatic heart disease and stroke in descending order. The reduction in the mortality rate due to CVDs is slower than for communicable, maternal, neonatal and nutritional disease mortalities. As a result, CVDs are the leading cause of mortality in Ethiopia. These findings urge Ethiopia to consider CVDs as a priority public health problem.

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