scholarly journals Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer

2020 ◽  
Vol 92 (5) ◽  
pp. 3674-3681 ◽  
Author(s):  
Jonathan P. Williams ◽  
Lindsay J. Morrison ◽  
Jeffery M. Brown ◽  
Joseph S. Beckman ◽  
Valery G. Voinov ◽  
...  
Keyword(s):  
Electron Capture ◽  
Mass Spectrometer ◽  
Electron Capture Dissociation ◽  
Ion Mobility ◽  
Protein Complexes ◽  
Native Protein ◽  
Top Down ◽  
Denatured Proteins

scholarly journals Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein

2015 ◽  
Vol 17 (16) ◽  
pp. 10538-10550 ◽  
Author(s):  
Sophie R. Harvey ◽  
Massimiliano Porrini ◽  
Robert C. Tyler ◽  
Cait E. MacPhee ◽  
Brian F. Volkman ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry ◽  
Top Down ◽  
Conformational Diversity ◽  
Metamorphic Protein

Ion mobility mass spectrometry can be combined with data from top-down sequencing to discern adopted conformations of proteins in the absence of solvent.

Top Down Characterization of Larger Proteins (45 kDa) by Electron Capture Dissociation Mass Spectrometry

2002 ◽  
Vol 124 (4) ◽  
pp. 672-678 ◽  
Author(s):  
Ying Ge ◽  
Brian G. Lawhorn ◽  
Mariam ElNaggar ◽  
Erick Strauss ◽  
Joo-Heon Park ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Top Down

scholarly journals Proteoform Differentiation using Tandem Trapped Ion Mobility, Electron Capture Dissociation, and ToF Mass Spectrometry

2021 ◽  
Author(s):  
Kevin Jeanne Dit Fouque ◽  
Desmond Kaplan ◽  
Valery G. Voinov ◽  
Frederik H. V. Holck ◽  
Ole N. Jensen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Ion Mobility ◽  
Trapped Ion
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