scholarly journals Building Block Based Construction of Membrane-Organelle Double Targeted Nanosystem for Two-Drug Delivery

2018 ◽  
Vol 29 (11) ◽  
pp. 3677-3685 ◽  
Author(s):  
Rafael R. Castillo ◽  
Daniel Lozano ◽  
María Vallet-Regí
Keyword(s):  
Drug Delivery ◽  
Building Block ◽  
Block Based ◽  
Membrane Organelle

Load-Transmitter Constraint Sets: Part I—An Effective Tool for Visualizing Load Flow in Compliant Mechanisms and Structures

2010 ◽  
Author(s):  
Girish Krishnan ◽  
Charles Kim ◽  
Sridhar Kota
Keyword(s):  
Building Block ◽  
Deformation Behavior ◽  
Design Methodology ◽  
Compliant Mechanisms ◽  
Compliant Mechanism ◽  
Load Flow ◽  
Mathematical Framework ◽  
Design Synthesis ◽  
Fundamental Building Block ◽  
Block Based

Visualizing load flow aids in conceptual design synthesis of machine components. In this paper, we present a mathematical framework to visualize load flow in compliant mechanisms and structures. This framework uses the concept of transferred forces to quantify load flow from input to the output of a compliant mechanism. The key contribution of this paper is the identification a fundamental building block known as the Load-Transmitter Constraint (LTC) set, which enables load flow in a particular direction. The transferred force in each LTC set is shown to be independent of successive LTC sets that are attached to it. This enables a continuous visualization of load flow from the input to the output. Furthermore, we mathematically relate the load flow with the deformation behavior of the mechanism. We can thus explain the deformation behavior of a number of compliant mechanisms from literature by identifying its LTC sets to visualize load flow. This method can also be used to visualize load flow in optimal stiff structure topologies. The insight obtained from this visualization tool facilitates a systematic building block based design methodology for compliant mechanisms and structural topologies.

scholarly journals Restriction of Conformation Transformation in Excited State: An Aggregation-Induced Emission Building Block Based on Stable Exocyclic C=N Group

iScience ◽  
2020 ◽  
Vol 23 (10) ◽  
pp. 101587
Author(s):  
Wentao Yu ◽  
Han Zhang ◽  
Ping-An Yin ◽  
Fan Zhou ◽  
Zhiming Wang ◽  
...  
Keyword(s):  
Excited State ◽  
Building Block ◽  
Aggregation Induced Emission ◽  
Block Based

A Flexible Discrete Building Block Synthesis Approach As Basis for the Design of Planar Linkages

2017 ◽  
Author(s):  
Simon Laudahn ◽  
Franz Irlinger ◽  
Kassim Abdul-Sater
Keyword(s):  
Building Block ◽  
Integrated Design ◽  
Optimal Solution ◽  
Design Tool ◽  
Grid Search ◽  
Approximate Synthesis ◽  
Synthesis Procedure ◽  
Block Based ◽  
Planar Linkages ◽  
Synthesis Approach

In this paper we present a computational approximate synthesis procedure for the planar RR chain. Our approach is based on a grid search and takes an arbitrary amount of user-defined task positions for the two outer bodies of the chain and restrictions for both joints into account. The result of this synthesis approach is not only one optimal solution, but a list of several possible solutions which are ranked according to their performance. The approach aims at being used in building block-based synthesis procedures of more complex linkages. The method shall later be included into a CAD-integrated design tool for planar linkages.

An Electron-Deficient Building Block Based on the B←N Unit: An Electron Acceptor for All-Polymer Solar Cells

2015 ◽  
Vol 55 (4) ◽  
pp. 1436-1440 ◽  
Author(s):  
Chuandong Dou ◽  
Xiaojing Long ◽  
Zicheng Ding ◽  
Zhiyuan Xie ◽  
Jun Liu ◽  
...  
Keyword(s):  
Solar Cells ◽  
Electron Acceptor ◽  
Building Block ◽  
Polymer Solar Cells ◽  
Block Based

Conceptual designs of multi-degree of freedom compliant parallel manipulators composed of wire-beam based compliant mechanisms

2014 ◽  
Vol 229 (3) ◽  
pp. 538-555 ◽  
Author(s):  
Guangbo Hao ◽  
Haiyang Li
Keyword(s):  
Rigid Body ◽  
Building Block ◽  
Compliant Mechanisms ◽  
Building Blocks ◽  
Parallel Manipulators ◽  
Parallel Mechanisms ◽  
Type Synthesis ◽  
Conceptual Designs ◽  
Rigid Body Model ◽  
Block Based

This paper proposes conceptual designs of multi-degree(s) of freedom (DOF) compliant parallel manipulators (CPMs) including 3-DOF translational CPMs and 6-DOF CPMs using a building block based pseudo-rigid-body-model (PRBM) approach. The proposed multi-DOF CPMs are composed of wire-beam based compliant mechanisms (WBBCMs) as distributed-compliance compliant building blocks (CBBs). Firstly, a comprehensive literature review for the design approaches of compliant mechanisms is conducted, and a building block based PRBM is then presented, which replaces the traditional kinematic sub-chain with an appropriate multi-DOF CBB. In order to obtain the decoupled 3-DOF translational CPMs (XYZ CPMs), two classes of kinematically decoupled 3-PPPR (P: prismatic joint, R: revolute joint) translational parallel mechanisms (TPMs) and 3-PPPRR TPMs are identified based on the type synthesis of rigid-body parallel mechanisms, and WBBCMs as the associated CBBs are further designed. Via replacing the traditional actuated P joint and the traditional passive PPR/PPRR sub-chain in each leg of the 3-DOF TPM with the counterpart CBBs (i.e. WBBCMs), a number of decoupled XYZ CPMs are obtained by appropriate arrangements. In order to obtain the decoupled 6-DOF CPMs, an orthogonally-arranged decoupled 6-PSS (S: spherical joint) parallel mechanism is first identified, and then two example 6-DOF CPMs are proposed by the building block based PRBM method. It is shown that, among these designs, two types of monolithic XYZ CPM designs with extended life have been presented.

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