A Photostable Far-Red/Near-Infrared Conjugated Polymer Photosensitizer with Aggregation-Induced Emission for Image-Guided Cancer Cell Ablation

2016 ◽  
Vol 49 (14) ◽  
pp. 5017-5025 ◽  
Author(s):  
Wenbo Wu ◽  
Guangxue Feng ◽  
Shidang Xu ◽  
Bin Liu
Keyword(s):  
Cancer Cell ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Aggregation Induced Emission ◽  
Image Guided ◽  
Cell Ablation

Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation

2016 ◽  
Vol 4 (1) ◽  
pp. 169-176 ◽  
Author(s):  
Youyong Yuan ◽  
Shidang Xu ◽  
Chong-Jing Zhang ◽  
Ruoyu Zhang ◽  
Bin Liu
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Normal Cell ◽  
Aggregation Induced Emission ◽  
Image Guided ◽  
Cell Ablation

The currently available photosensitizers (PSs) for photodynamic therapy (PDT) can easily lead to undesirable normal cell death due to their intrinsic photo-toxicity and lack of selectivity for cancer cells.

Far Red/Near-Infrared AIE Dots for Image-Guided Photodynamic Cancer Cell Ablation

2016 ◽  
Vol 8 (33) ◽  
pp. 21193-21200 ◽  
Author(s):  
Guangxue Feng ◽  
Wenbo Wu ◽  
Shidang Xu ◽  
Bin Liu
Keyword(s):  
Cancer Cell ◽  
Near Infrared ◽  
Image Guided ◽  
Cell Ablation

scholarly journals Organelle-specific bioprobes based on fluorogens with aggregation-induced emission (AIE) characteristics

2016 ◽  
Vol 14 (42) ◽  
pp. 9931-9944 ◽  
Author(s):  
Fang Hu ◽  
Bin Liu
Keyword(s):  
Cancer Cell ◽  
Aggregation Induced Emission ◽  
Image Guided ◽  
Cell Ablation

A number of aggregation-induced emission (AIE) probes with high photostability and specificity have been developed for organelle imaging and image-guided cancer cell ablation.

High performance photosensitizers with aggregation-induced emission for image-guided photodynamic anticancer therapy

2017 ◽  
Vol 4 (6) ◽  
pp. 1110-1114 ◽  
Author(s):  
Wenbo Wu ◽  
Duo Mao ◽  
Shidang Xu ◽  
Shenglu Ji ◽  
Fang Hu ◽  
...  
Keyword(s):  
High Performance ◽  
Near Infrared ◽  
Anticancer Therapy ◽  
Infrared Emission ◽  
Aggregation Induced Emission ◽  
Image Guided ◽  
Near Infrared Emission

A series of D–A′–π–A type photosensitizers were designed and synthesized to show strong aggregation-induced far red and near infrared emission and very effective 1O2 generation simultaneously, and have been successfully used for image-guided photodynamic anticancer therapy.

Artemisinin and AIEgen Conjugate for Mitochondria-Targeted and Image-Guided Chemo- and Photodynamic Cancer Cell Ablation

2018 ◽  
Vol 10 (14) ◽  
pp. 11546-11553 ◽  
Author(s):  
Guangxue Feng ◽  
Jie Liu ◽  
Chong-Jing Zhang ◽  
Bin Liu
Keyword(s):  
Cancer Cell ◽  
Image Guided ◽  
Cell Ablation

Conjugated polymer microparticles for selective cancer cell image-guided photothermal therapy

2015 ◽  
Vol 3 (6) ◽  
pp. 1135-1141 ◽  
Author(s):  
Guangxue Feng ◽  
Jie Liu ◽  
Junlong Geng ◽  
Bin Liu
Keyword(s):  
Cancer Cell ◽  
Conjugated Polymer ◽  
Photothermal Therapy ◽  
Image Guided ◽  
Cell Image ◽  
Infrared Laser Irradiation ◽  
Surface Decoration ◽  
Polymer Microparticles ◽  
Nih 3T3 ◽  
Mcf 7

We report conjugated polymers (CPs) microparticles (MPs) for selective cancer cell image-guided photothermal therapy. The CPMPs without surface functionalization can target MCF-7 cancer cells over NIH-3T3 normal cells, while nanoparticles need surface decoration to possess selectivity. Benefitting from large absorption, bright fluorescence, and efficient light-to-heat conversion of CPs, the fabricated MPs can selectively kill MCF-7 cells under NIR infrared laser irradiation.

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