Fabrication of Microfiber-Templated Microfluidic Chips with Microfibrous Channels for High Throughput and Continuous Production of Nanoscale Droplets

2022 ◽  
pp. 127-134
Author(s):  
Guk-Young Ahn ◽  
Inseong Choi ◽  
Minju Song ◽  
Soo Kyung Han ◽  
Kangho Choi ◽  
...  
Keyword(s):  
High Throughput ◽  
Continuous Production ◽  
Microfluidic Chips

scholarly journals The Fabrication and Application Mechanism of Microfluidic Systems for High Throughput Biomedical Screening: A Review

Micromachines ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 297 ◽  
Author(s):  
Kena Song ◽  
Guoqiang Li ◽  
Xiangyang Zu ◽  
Zhe Du ◽  
Liyu Liu ◽  
...  
Keyword(s):  
High Throughput ◽  
New Technologies ◽  
Biomedical Application ◽  
Raw Materials ◽  
Physical Structure ◽  
Microfluidic System ◽  
Microfluidic Chips ◽  
Microfluidic Systems ◽  
Microfluidic Technology

Microfluidic systems have been widely explored based on microfluidic technology, and it has been widely used for biomedical screening. The key parts are the fabrication of the base scaffold, the construction of the matrix environment in the 3D system, and the application mechanism. In recent years, a variety of new materials have emerged, meanwhile, some new technologies have been developed. In this review, we highlight the properties of high throughput and the biomedical application of the microfluidic chip and focus on the recent progress of the fabrication and application mechanism. The emergence of various biocompatible materials has provided more available raw materials for microfluidic chips. The material is not confined to polydimethylsiloxane (PDMS) and the extracellular microenvironment is not limited by a natural matrix. The mechanism is also developed in diverse ways, including its special physical structure and external field effects, such as dielectrophoresis, magnetophoresis, and acoustophoresis. Furthermore, the cell/organ-based microfluidic system provides a new platform for drug screening due to imitating the anatomic and physiologic properties in vivo. Although microfluidic technology is currently mostly in the laboratory stage, it has great potential for commercial applications in the future.

High-throughput roll-to-roll fabrication of flexible thermochromic coatings for smart windows with VO2 nanoparticles

2018 ◽  
Vol 6 (13) ◽  
pp. 3451-3458 ◽  
Author(s):  
Youngkwang Kim ◽  
Sangbae Yu ◽  
Jaeseoung Park ◽  
Daseob Yoon ◽  
Amir Masoud Dayaghi ◽  
...  
Keyword(s):  
High Throughput ◽  
Continuous Production ◽  
Smart Windows ◽  
Roll To Roll

Here, we demonstrate the scalable and continuous production of large coatings with thermochromic VO2 nanoparticles for “smart” windows.

Simple, fast and high-throughput single-cell analysis on PDMS microfluidic chips

2008 ◽  
Vol 29 (24) ◽  
pp. 5055-5060 ◽  
Author(s):  
Linfen Yu ◽  
Huaiqing Huang ◽  
Xiuling Dong ◽  
Dapeng Wu ◽  
Jinhua Qin ◽  
...  
Keyword(s):  
Single Cell ◽  
High Throughput ◽  
Single Cell Analysis ◽  
Cell Analysis ◽  
Microfluidic Chips

High-throughput continuous production of liposomes using hydrodynamic flow-focusing microfluidic devices

2017 ◽  
Vol 156 ◽  
pp. 349-357 ◽  
Author(s):  
Mariano Michelon ◽  
Davi Rocha Bernardes Oliveira ◽  
Guilherme de Figueiredo Furtado ◽  
Lucimara Gaziola de la Torre ◽  
Rosiane Lopes Cunha
Keyword(s):  
High Throughput ◽  
Continuous Production ◽  
Microfluidic Devices ◽  
Hydrodynamic Flow ◽  
Flow Focusing

Leaf-templated, microwell-integrated microfluidic chips for high-throughput cell experiments

2018 ◽  
Vol 10 (2) ◽  
pp. 025008 ◽  
Author(s):  
Mao Mao ◽  
Jiankang He ◽  
Yongjie Lu ◽  
Xiao Li ◽  
Tianjiao Li ◽  
...  
Keyword(s):  
High Throughput ◽  
Microfluidic Chips

scholarly journals High-throughput sorting of drops in microfluidic chips using electric capacitance

2015 ◽  
Vol 9 (4) ◽  
pp. 044116 ◽  
Author(s):  
Arjen M. Pit ◽  
Riëlle de Ruiter ◽  
Anand Kumar ◽  
Daniel Wijnperlé ◽  
Michèl H. G. Duits ◽  
...  
Keyword(s):  
High Throughput ◽  
Microfluidic Chips ◽  
Electric Capacitance

scholarly journals X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization

2017 ◽  
Vol 11 (2) ◽  
pp. 024118 ◽  
Author(s):  
Jeremy M. Schieferstein ◽  
Ashtamurthy S. Pawate ◽  
Chang Sun ◽  
Frank Wan ◽  
Paige N. Sheraden ◽  
...  
Keyword(s):  
Membrane Protein ◽  
High Throughput ◽  
High Throughput Screening ◽  
Protein Crystallization ◽  
Microfluidic Chips ◽  
X Ray ◽  
Membrane Protein Crystallization

scholarly journals Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
H. B. Atakan ◽  
R. Xiang ◽  
M. Cornaglia ◽  
L. Mouchiroud ◽  
E. Katsyuba ◽  
...  
Keyword(s):  
High Throughput ◽  
Agar Plate ◽  
Model Organism ◽  
Suitable Model ◽  
Microfluidic Chips ◽  
Long Term Culture ◽  
C Elegans ◽  
Bleaching Procedure ◽  
Automated Platform

Abstract The nematode Caenorhabditis elegans is a suitable model organism in drug screening. Traditionally worms are grown on agar plates, posing many challenges for long-term culture and phenotyping of animals under identical conditions. Microfluidics allows for ‘personalized’ phenotyping, as microfluidic chips permit collecting individual responses over worms’ full life. Here, we present a multiplexed, high-throughput, high-resolution microfluidic approach to culture C. elegans from embryo to the adult stage at single animal resolution. We allocated single embryos to growth chambers, for observing the main embryonic and post-embryonic development stages and phenotypes, while exposing worms to up to 8 different well-controlled chemical conditions. Our approach allowed eliminating bacteria aggregation and biofilm formation-related clogging issues, which enabled us performing up to 80 hours of automated single worm culture studies. Our microfluidic platform is linked with an automated phenotyping code that registers organism-associated phenotypes at high-throughput. We validated our platform with a dose-response study of the anthelmintic drug tetramisole by studying its influence through the life cycle of the nematodes. In parallel, we could observe development effects and variations in single embryo and worm viability due to the bleaching procedure that is standardly used for harvesting the embryos from a worm culture agar plate.

scholarly journals A simple method for production of hydrophilic, rigid, and sterilized multi-layer 3D integrated polydimethylsiloxane microfluidic chips

Lab on a Chip ◽  
2020 ◽  
Vol 20 (13) ◽  
pp. 2354-2363 ◽  
Author(s):  
Tomoko Gowa Oyama ◽  
Kotaro Oyama ◽  
Mitsumasa Taguchi
Keyword(s):  
Electron Beam ◽  
High Throughput ◽  
Microfluidic Chips ◽  
Simple Method ◽  
High Throughput Method ◽  
Γ Ray

We have developed a high-throughput method for obtaining hydrophilic, rigid, low-absorption/adsorption, and sterilized multi-layer 3D integrated PDMS microfluidic chips simply by applying electron beam or γ-ray irradiation to stacked PDMS layers.

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