scholarly journals Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin-2 Receptor

2020 ◽  
Vol 3 (4) ◽  
pp. 706-719
Author(s):  
Paris Avgoustou ◽  
Ameera B. A. Jailani ◽  
Jean-Olivier Zirimwabagabo ◽  
Matthew J. Tozer ◽  
Karl R. Gibson ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Antagonist

A small molecule antagonist of ghrelin O-acyltransferase (GOAT)

2011 ◽  
Vol 47 (26) ◽  
pp. 7512 ◽  
Author(s):  
Amanda L. Garner ◽  
Kim D. Janda
Keyword(s):  
Small Molecule ◽  
Small Molecule Antagonist

scholarly journals Idalopirdine – a small molecule antagonist of 5-HT6 with therapeutic potential against obesity

2015 ◽  
Vol 30 (6) ◽  
pp. 1487-1494 ◽  
Author(s):  
Magdalena Dudek ◽  
Monika Marcinkowska ◽  
Adam Bucki ◽  
Adrian Olczyk ◽  
Marcin Kołaczkowski
Keyword(s):  
Small Molecule ◽  
Therapeutic Potential ◽  
Small Molecule Antagonist

The novel small-molecule antagonist MMG-11 preferentially inhibits TLR2/1 signaling

2020 ◽  
Vol 171 ◽  
pp. 113687 ◽  
Author(s):  
Maria Grabowski ◽  
Manuela S. Murgueitio ◽  
Marcel Bermudez ◽  
Gerhard Wolber ◽  
Günther Weindl
Keyword(s):  
Small Molecule ◽  
The Novel ◽  
Small Molecule Antagonist

scholarly journals A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis

2015 ◽  
Vol 76 (4) ◽  
pp. 891-901 ◽  
Author(s):  
Liang Fang ◽  
Qionghua Zhu ◽  
Martin Neuenschwander ◽  
Edgar Specker ◽  
Annika Wulf-Goldenberg ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Small Molecule ◽  
The Self ◽  
Self Renewal ◽  
Small Molecule Antagonist

Chimeric protein probes for C5a receptors through fusion of the anaphylatoxin C5a core region with a small-molecule antagonist

2019 ◽  
Vol 62 (10) ◽  
pp. 1371-1378 ◽  
Author(s):  
Chao Zuo ◽  
Wei-Wei Shi ◽  
Xiao-Xu Chen ◽  
Marie Glatz ◽  
Bernd Riedl ◽  
...  
Keyword(s):  
Small Molecule ◽  
Chimeric Protein ◽  
Core Region ◽  
Small Molecule Antagonist ◽  
Anaphylatoxin C5a ◽  
C5a Receptors
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