scholarly journals Narrow Aperture Detection Electrodes ICR Cell with Quadrupolar Ion Detection for FT-ICR MS at the Cyclotron Frequency

2020 ◽  
Vol 31 (11) ◽  
pp. 2258-2269
Author(s):  
Konstantin O. Nagornov ◽  
Anton N. Kozhinov ◽  
Edith Nicol ◽  
Oleg Yu. Tsybin ◽  
David Touboul ◽  
...  
Keyword(s):  
Cyclotron Frequency ◽  
Ion Detection ◽  
Ft Icr Ms ◽  
Ft Icr

PHYTOCHEMICAL SCREENING, ANTIOXIDANT, ANTI-CYTOTOXIC AND ANTICANCER EFFECTS OF GALINSOGA PARVIFLORA AND VERNONIA POLYANTHES (ASTERACEAE) EXTRACTS

2020 ◽  
Vol 8 (10) ◽  
pp. 84-98
Author(s):  
Sula M. V. Feleti ◽  
Renê L. Aleluia ◽  
Suiany V. Gervásio ◽  
Jean Carlos V. Dutra ◽  
Jessica R. P. Oliveira ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Phenolic Acids ◽  
Unsaturated Fatty Acids ◽  
Biological Effects ◽  
Human Lymphocytes ◽  
Chemical Characterization ◽  
Total Content ◽  
Ags Cells ◽  
Ft Icr Ms ◽  
Ft Icr

The study was designed to investigate the chemical composition and the biological effects of G. parviflora and V. polyanthes ethanolic extracts in vitro. Total content of phenols, flavonoids and tannins was quantified by spectrophotometry; chemical characterization was permed by mass spectrometry (ESI (-) FT-ICR MS and APCI (+) FT-ICR MS analysis). Antioxidant activities were determined by FRAP and Fe2+ chelating methods. Extracts cytotoxicity was evaluated in human lymphocytes, sarcoma-180 (S-180) and human gastric adenocarcinoma (AGS) cells, by MTT assay. V. polyanthes presented higher total content of tannins and G. parviflora presented higher amount of phenols and flavonoids. Chemical characterization showed the presence of flavonoids, phenolic acids and sesquiterpene lactones in V. polyanthes extract, and steroids, phenolic acids and fatty acids (Poly Unsaturated Fatty Acids - PUFA) in G. parviflora extract. V. polyanthes extract stood out in the Fe2+ chelation test. G. parviflora extract did not present outstanding antioxidant results in the tested protocols. Both species showed a tendency to promote cytotoxicity in human lymphocyte cells. Regarding the antiproliferative effect, both species were able to reduce S-180 cell viability and G. parviflora extract showed high antiproliferative potential in the assay with AGS cells. These findings reinforce the medicinal use of these plants, as well as suggest their potential use for the development of new drugs and for the treatment of cancers.

Application of frequency multiple FT-ICR-MS signal acquisition for improved proteome research

2021 ◽  
pp. 116578
Author(s):  
Sung-Gun Park ◽  
Jared P. Mohr ◽  
Gordon A. Anderson ◽  
James E. Bruce
Keyword(s):  
Signal Acquisition ◽  
Ft Icr Ms ◽  
Ft Icr

Molecular insights into the reactivity of aquatic natural organic matter towards hydroxyl (•OH) and sulfate (SO4•−) radicals using FT-ICR MS

2021 ◽  
Vol 425 ◽  
pp. 130622
Author(s):  
Suona Zhang ◽  
Zhineng Hao ◽  
Jingfu Liu ◽  
Leo Gutierrez ◽  
Jean-Philippe Croué
Keyword(s):  
Organic Matter ◽  
Natural Organic Matter ◽  
Ft Icr Ms ◽  
Ft Icr

Pseudomolecular ion formation of explosives in FT-ICR-MS

1994 ◽  
Author(s):  
Choo Seng Giam ◽  
T. L. Holliday ◽  
M. S. Ahmed ◽  
G. E. Reed ◽  
G. Zhao
Keyword(s):  
Ion Formation ◽  
Ft Icr Ms ◽  
Ft Icr

Advanced Strategies for Proton-Transfer Reactions Coupled with Parallel Ion Parking on a 21 T FT-ICR MS for Intact Protein Analysis

2021 ◽  
Author(s):  
Chad R. Weisbrod ◽  
Lissa C. Anderson ◽  
Christopher L. Hendrickson ◽  
Leah V. Schaffer ◽  
Michael R. Shortreed ◽  
...  
Keyword(s):  
Proton Transfer ◽  
Protein Analysis ◽  
Transfer Reactions ◽  
Intact Protein ◽  
Proton Transfer Reactions ◽  
Intact Protein Analysis ◽  
Ft Icr Ms ◽  
Ft Icr

Asphaltenes subfractions characterization and calculation of their solubility parameter using ESI(-) FT-ICR MS: Part II

Fuel ◽  
2022 ◽  
Vol 312 ◽  
pp. 122864
Author(s):  
Fernanda E. Pinto ◽  
Victor R. Fonseca ◽  
Lindamara M. Souza ◽  
Luciana A. Terra ◽  
Sreedhar Subramanian ◽  
...  
Keyword(s):  
Solubility Parameter ◽  
Ft Icr Ms ◽  
Ft Icr
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