Rapid Determination of Domoic Acid in Serum and Urine by Liquid Chromatography−Electrospray Tandem Mass Spectrometry

2003 ◽  
Vol 51 (7) ◽  
pp. 1791-1796 ◽  
Author(s):  
Elizabeth R. Tor ◽  
Birgit Puschner ◽  
William E. Whitehead
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Domoic Acid ◽  
Rapid Determination ◽  
Tandem Mass ◽  
Electrospray Tandem Mass Spectrometry ◽  
Serum And Urine

scholarly journals Rapid Determination of Fosetyl-Aluminum Residues in Lettuce by Liquid Chromatography/Electrospray Tandem Mass Spectrometry

2003 ◽  
Vol 86 (4) ◽  
pp. 832-838 ◽  
Author(s):  
Félix Hernández ◽  
Juan V Sancho ◽  
Óscar J Pozo ◽  
Carme Villaplana ◽  
María Ibáñez ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Limit Of Detection ◽  
Rapid Determination ◽  
Tandem Mass ◽  
Electrospray Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Limit Of Quantitation

Abstract This paper describes a new method for the sensitive and selective determination of fosetyl-aluminum (Al) residues in vegetable samples. The method involves extraction with water by using a high-speed blender and subsequent injection of the 5-fold diluted extract into the liquid chromatograph. Fosetyl-Al is determined by liquid chromatography with electrospray tandem mass spectrometry after the addition of tetrabutylammonium acetate as the ion-pairing re-agent. The method has been used to assay lettuce samples spiked at 2 and 0.2 mg/kg. Recoveries were satisfactory, with mean values of 98 and 106%, respectively, and relative standard deviations were <10%. The limit of quantitation was 0.2 mg/kg, and the limit of detection was as low as 0.05 mg/kg. Matrix-matched calibration was used for quantitation, and the addition of an internal standard improved repeatability. The developed method allows the accurate and rapid determination of low levels of fosetyl-Al residues in lettuce with very little sample handling and good sensitivity; it was shown to be robust by the analysis of almost 100 samples.

scholarly journals Rapid Determination of Orotic Acid in Urine by Liquid Chromatography–Electrospray Tandem Mass Spectrometry

2003 ◽  
Vol 49 (3) ◽  
pp. 499-501 ◽  
Author(s):  
Mohamed S Rashed ◽  
Minnie Jacob ◽  
Mohamed Al-Amoudi ◽  
Zuhair Rahbeeni ◽  
Moeen A D Al-Sayed ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Orotic Acid ◽  
Rapid Determination ◽  
Tandem Mass ◽  
Electrospray Tandem Mass Spectrometry
Sign in / Sign up

Export Citation Format

Share Document