Superparamagnetic Iron Oxide Nanoparticles with Rigid Cross-linked Polyethylene Glycol Fumarate Coating for Application in Imaging and Drug Delivery

2009 ◽  
Vol 113 (19) ◽  
pp. 8124-8131 ◽  
Author(s):  
Morteza Mahmoudi ◽  
Abdolreza Simchi ◽  
Mohammad Imani ◽  
Urs O. Häfeli
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

Impact of the chain length on the biodistribution profiles of PEGylated iron oxide nanoparticles: a multimodal imaging study

2021 ◽  
Author(s):  
Dimitri Stanicki ◽  
Lionel Larbanoix ◽  
Sébastien Boutry ◽  
Thomas Vangijzegem ◽  
Indiana Ternad ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Iron Oxide ◽  
Chain Length ◽  
Iron Oxide Nanoparticles ◽  
Multimodal Imaging ◽  
Imaging Study ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Chain Lengths

Bimodal sub-5 nm superparamagnetic iron oxide nanoparticles (SPIO-5) coated with polyethylene glycol of different chain lengths (i.e. PEG-800, -2000 and -5000) have been prepared and characterized.

ß-Amido Acid Functionalised Superparamagnetic Iron Oxide Nanoparticles as a Novel Carrier for Efficient Delivery of Doxorubicine

2017 ◽  
Vol 41 (3) ◽  
pp. 129-135
Author(s):  
Fatemeh Ebrahimi ◽  
Maryam Karimi ◽  
Hasan Sereshti ◽  
Mohsen Yousefifar
Keyword(s):  
Electron Microscopy ◽  
Drug Delivery ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Precipitation Method ◽  
Hydrodynamic Diameter ◽  
Oxide Nanoparticles ◽  
Amido Acid

Superparamagnetic iron oxide nanoparticles are increasingly used in medical applications due to their unique physical properties. They are useful carriers for delivering antitumour drugs in targeted cancer treatment. In this study, amido acid-functionalised magnetic nanoparticles (AAFMNs) are used as drug-delivery vehicles for doxorubicine as an efficient tool for the treatment of cancer. Magnetic iron oxide nanoparticles were synthesised using a co-precipitation method. The prepared iron oxide nanoparticles were then functionalised with amido acid functional groups. Finally, the synthesised AAFMNs were used for the delivery of doxorubicine. AAFMNs were characterised by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, thermogravimetric analysis and zeta potential. An in vitro-determined hydrodynamic diameter of ∼80 nm suggested their applicability for this purpose. The findings show that AAFMNs are a promising tool for potential magnetic drug delivery.

scholarly journals Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles

2018 ◽  
Vol Volume 13 ◽  
pp. 8443-8460 ◽  
Author(s):  
Jasmin Matuszak ◽  
Barbara Lutz ◽  
Aleksander Sekita ◽  
Jan Zaloga ◽  
Christoph Alexiou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Atherosclerotic Plaques
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