Large Scale Domain Alignment of a Block Copolymer from Solution Using Electric Fields

2002 ◽  
Vol 35 (4) ◽  
pp. 1319-1325 ◽  
Author(s):  
Alexander Böker ◽  
Armin Knoll ◽  
Hubert Elbs ◽  
Volker Abetz ◽  
Axel H. E. Müller ◽  
...  
Soft Matter ◽  
2006 ◽  
Vol 2 (12) ◽  
pp. 1089-1094 ◽  
Author(s):  
Violetta Olszowka ◽  
Markus Hund ◽  
Volker Kuntermann ◽  
Sabine Scherdel ◽  
Larisa Tsarkova ◽  
...  

1998 ◽  
Vol 31 (13) ◽  
pp. 4399-4401 ◽  
Author(s):  
P. Mansky ◽  
J. DeRouchey ◽  
T. P. Russell ◽  
J. Mays ◽  
M. Pitsikalis ◽  
...  

2012 ◽  
Vol 24 (18) ◽  
pp. 2390-2397 ◽  
Author(s):  
Tandra Ghoshal ◽  
Tuhin Maity ◽  
Jeffrey F. Godsell ◽  
Saibal Roy ◽  
Michael A. Morris

Author(s):  
Charles F. Kennel

Around the time the steady convection model was being developed, Akasofu (1964) was arranging ground-based magnetometer and all-sky camera observations of the complex time dependence of nightside auroral activity into the central phenomenological conception of tune-dependent magnetospheric physics—the auroral substorm. In this chapter, we assemble a description of a substorm from modern observations. We will see that observations of electric fields, auroral X rays, cosmic noise absorption, ionospheric density, and geomagnetic micropulsations have also been successfully ordered by the substorm paradigm. At the same time, it will become clear that each individual substorm has its own irreducible individuality, and that our summary description is really a list of effects that anyone thinking about substorms ought to consider. No real substorm will look exactly like the one described here. Spacecraft observations of auroral light, precipitation, currents, and fields from polar orbit have held out high promise for unified understanding of the development of the auroral substorm around the entire oval. Without truly global auroral observations, it would be difficult to establish decisive contact with observations of large-scale convection and the associated changes in magnetospheric configuration. Despite the high promise and the many other successes of spacecraft observations of the aurora, synthetic understanding of the time development of the auroral substorm at all local times, dayside and nightside, evening and dawn, has been slow in emerging, perhaps because a stringent combination of field of view, sensitivity, space and time resolution, and multispectral capability is required. One needs images of the whole oval with sufficient space resolution to identify important arc structures (50-100 km or better) in a temporal sequence that can articulate the evolution of activity on better than the 10-minute time scale on which polar cap convection develops. Only recently has it been possible to observe auroral activity at all local tunes around the auroral oval simultaneously and follow its time development from the beginning of the growth phase until well into the expansion phase. This amplification of the original paradigm is the subject of Sections 12.2 and 12.3.


2007 ◽  
Vol 25 (6) ◽  
pp. 1311-1322 ◽  
Author(s):  
R. B. Cosgrove

Abstract. It has recently been shown, by computation of the linear growth rate, that midlatitude sporadic-E (Es) layers are subject to a large scale electrodynamic instability. This instability is a logical candidate to explain certain frontal structuring events, and polarization electric fields, which have been observed in Es layers by ionosondes, by coherent scatter radars, and by rockets. However, the original growth rate derivation assumed an infinitely thin Es layer, and therefore did not address the short wavelength cutoff. Also, the same derivation ignored the effects of F region loading, which is a significant wavelength dependent effect. Herein is given a generalized derivation that remedies both these short comings, and thereby allows a computation of the wavelength dependence of the linear growth rate, as well as computations of various threshold conditions. The wavelength dependence of the linear growth rate is compared with observed periodicities, and the role of the zeroth order meridional wind is explored. A three-dimensional paper model is used to explain the instability geometry, which has been defined formally in previous works.


2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi282-vi282
Author(s):  
Jeffrey Arle ◽  
Eric Wong ◽  
Anders Korshoej ◽  
Socrates Dokos ◽  
Ze’ev Bomzon ◽  
...  

Abstract The efficacy of Tumor-Treating Fields (TTFields) rests on the result of a large-scale clinical trial that demonstrated an increase in the survival of newly diagnosed glioblastoma patients when combined with temozolomide chemotherapy. Overall survival now extends to over 60 months in some of our patients when dexamethasone, which we suspected of interference with TTFields effects, is replaced with celecoxib to control tumor-associated inflammation. The transcranial method of delivering TTFields has not changed in light of ongoing advances in deep brain stimulation (DBS) and transcranial electric stimulation (TES), notably that the resistivity of the skull is the principle obstacle to placing therapeutic electric field strength of 2 V/cm into target tumor sites and variation in skull thickness is the main difference in TES efficiency across individuals. Realistic human head finite element modeling (FEM) predicted that surgical craniectomy beneath TTFields’ electrodes would enhance field strength at target tumor sites. Here we show that 2 V/cm can be reliably delivered to tumor sites using minimally-invasive DBS cylindrical leads or ribbon electrode arrays, pre- or post-resection. Two objections arise to the in situ method: 1) Will TTFields stimulate axons in situ? 2) Will field strength exceed safety limits for cell damage? Neural stimulation modeling and experiments show that TTFields’ frequency of 200 kHz, 1–3 orders of magnitude higher than ion channel time constants, is too high to stimulate them. Furthermore, 2 V/cm is well below cell damage limits of 700 V/mm. Thus we propose a new delivery method to improve tumor control in glioblastoma patients and to provide valuable information on TTFields’ effects via cell studies using in situ electric fields at 200 kHz.


Small ◽  
2015 ◽  
Vol 11 (45) ◽  
pp. 6058-6064 ◽  
Author(s):  
Clemens Liedel ◽  
Christian Lewin ◽  
Larisa Tsarkova ◽  
Alexander Böker

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