Modification of Poly(lactic acid) Films:  Enhanced Wettability from Surface-Confined Photografting and Increased Degradation Rate Due to an Artifact of the Photografting Process

Abstract Poly-lactic acid based biocomposite strengthened with magnesium alloy wires (Mg wires/PLA composite) is prepared for bone fixation implantation. The influence of wire content and load mode on the degradation performances of the composite and its components is studied. The result suggests the degradation of Mg wires could slow down the pH decrease originated from the degradation of PLA, while a relatively high wire content contributes to descend the degradation rate of Mg wire in the composite. Dynamic load significantly promotes the mechanical loss of the specimens. After 30 days immersion, the Sb retention is about 65%, 52% and 55%, respectively for pure PLA, the composite at 10 vol% and 20 vol% under dynamic load, comparing to 75%, 70% and 72% under no load. Moreover, dynamic load could further mitigate the degradation of Mg wires by increasing convective transport of acidic products out of the composite.

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Base-Catalyzed Hydrolysis Behavior of PLA/PBS Blends

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.821-822.941 ◽

2013 ◽

Vol 821-822 ◽

pp. 941-944

Author(s):

Shi Jie Zhang ◽

Yi Wen Tang ◽

Li Hua Cheng

Keyword(s):

Molecular Weight ◽

Lactic Acid ◽

Degradation Rate ◽

Degradation Process ◽

Poly Lactic Acid ◽

Biodegradable Materials ◽

Butylene Succinate ◽

New Type

Poly (butylene succinate) (PBS) was mixed with Poly (lactic acid) (PLA) through Haake Reomix, a new type of biodegradable materials can be obtained. With the increasing addition of PBS and the raise of the solution basicity, the degradation rate of blends increase sharply. The GPC analysis can approve the reduction of molecular weight in the degradation process of PLA/PBS blends.

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Controlling degradation rate of poly(lactic acid) for its biomedical applications

Biomedical Engineering Letters ◽

10.1007/s13534-011-0025-8 ◽

2011 ◽

Vol 1 (3) ◽

pp. 163-167 ◽

Cited By ~ 37

Author(s):

Catherine Shasteen ◽

Young Bin Choy

Keyword(s):

Lactic Acid ◽

Biomedical Applications ◽

Degradation Rate ◽

Poly Lactic Acid

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Tuning the hydrolytic degradation rate of poly-lactic acid (PLA) to more durable applications

10.1063/1.5016801 ◽

2017 ◽

Author(s):

Iozzino Valentina ◽

Askanian Haroutioun ◽

Leroux Fabrice ◽

Verney Vincent ◽

Pantani Roberto

Keyword(s):

Lactic Acid ◽

Degradation Rate ◽

Hydrolytic Degradation ◽

Poly Lactic Acid

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Amphiphilic biodegradable copolymer, poly(aspartic acid-co-lactide): acceleration of degradation rate and improvement of thermal stability for poly(lactic acid), poly(butylene succinate) and poly(ε-caprolactone)

Polymer Degradation and Stability ◽

10.1016/s0141-3910(02)00404-4 ◽

2003 ◽

Vol 80 (2) ◽

pp. 241-250 ◽

Cited By ~ 38

Author(s):

Hosei Shinoda ◽

Yukiko Asou ◽

Takeshi Kashima ◽

Takazo Kato ◽

Yvonne Tseng ◽

...

Keyword(s):

Thermal Stability ◽

Lactic Acid ◽

Aspartic Acid ◽

Degradation Rate ◽

Poly Lactic Acid ◽

Butylene Succinate ◽

Biodegradable Copolymer ◽

Copolymer Poly

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Research on Preparation and Hydrolysis Resistance of Poly(lactic acid) Modified by MDI

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.320.112 ◽

2011 ◽

Vol 320 ◽

pp. 112-117

Author(s):

Jian Jiang Shang ◽

Jian Ning Wu ◽

De Qiang Li ◽

Ya Xi Huang ◽

Ling Ming Zhao ◽

...

Keyword(s):

Lactic Acid ◽

Degradation Rate ◽

Addition Reaction ◽

Aqueous Media ◽

Poly Lactic Acid ◽

Diphenylmethane Diisocyanate ◽

Degradation Behavior ◽

The Stability ◽

Hydrolysis Resistance ◽

Degradation Properties

The poly(lactic acid) (PLA) was modified by 4,4'-diphenylmethane diisocyanate (MDI) successfully prepared to improve the stability of PLA. The MDI and the hydroxyl terminated PLA could form PLA modified by MDI (MDI-PLA) via addition reaction. The structure of MDI-PLA was confirmed by FTIR and its degradation properties were investigated. The results showed that the pH of the aqueous media and the ion strength together played an important role in the degradation behavior of the PLA and MDI-PLA. Both of the PLA and MDI-PLA had the highest degradation rate in 0.01 M NaOH. It offers the best stability to hydrolysis resistance by adding the 0.6 wt% of MDI to the PLA materials，and have a more stable of 15 times than unmodified PLA.

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