Synthesis of derivatives of prenylacetic acids by reactions of alkyl malonate, cyanoacetate, and acetoacetate with alkylating reagents in ionic liquids

2004 ◽  
Vol 53 (3) ◽  
pp. 652-658 ◽  
Author(s):  
G. V. Kryshtal ◽  
G. M. Zhdankina ◽  
S. G. Zlotin
Author(s):  
Chandrakant Sarode ◽  
Sachin Yeole ◽  
Ganesh Chaudhari ◽  
Govinda Waghulde ◽  
Gaurav Gupta

Aims: To develop an efficient protocol, which involves an elegant exploration of the catalytic potential of both the room temperature and surfactant ionic liquids towards the synthesis of biologically important derivatives of 2-aminothiazole. Objective: Specific heat capacity data as a function of temperature for the synthesized 2- aminothiazole derivatives has been advanced by exploring their thermal profiles. Method: The thermal gravimetry analysis and differential scanning calorimetry techniques are used systematically. Results: The present strategy could prove to be a useful general strategy for researchers working in the field of surfactants and surfactant based ionic liquids towards their exploration in organic synthesis. In addition to that, effect of electronic parameters on the melting temperature of the corresponding 2-aminothiazole has been demonstrated with the help of thermal analysis. Specific heat capacity data as a function of temperature for the synthesized 2-aminothiazole derivatives has also been reported. Conclusion: Melting behavior of the synthesized 2-aminothiazole derivatives is to be described on the basis of electronic effects with the help of thermal analysis. Additionally, the specific heat capacity data can be helpful to the chemists, those are engaged in chemical modelling as well as docking studies. Furthermore, the data also helps to determine valuable thermodynamic parameters such as entropy and enthalpy.


Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 652 ◽  
Author(s):  
Monika Olesiejuk ◽  
Agnieszka Kudelko ◽  
Marcin Swiatkowski ◽  
Rafal Kruszynski

New derivatives of 4-alkyl-3,5-diaryl-4H-1,2,4-triazole were synthesized utilizing the Suzuki cross-coupling reaction. The presented methodology comprises of the preparation of bromine-containing 4-alkyl-4H-1,2,4-triazoles and their coupling with different commercially available boronic acids in the presence of ionic liquids or in conventional solvents. The obtained compounds were tested for their luminescence properties.


RSC Advances ◽  
2020 ◽  
Vol 10 (15) ◽  
pp. 8653-8663 ◽  
Author(s):  
Anna Turguła ◽  
Konrad Stęsik ◽  
Katarzyna Materna ◽  
Tomasz Klejdysz ◽  
Tadeusz Praczyk ◽  
...  

Novel ionic liquids with cations based on alkyl derivatives of 1,4-diazabicyclo[2.2.2]octane (DABCO) and an anion derived from naturally occurring pelargonic acid possessed double biological functions: herbicidal and deterrent activity.


2014 ◽  
Vol 55 (25) ◽  
pp. 3565-3568 ◽  
Author(s):  
Marcin Smiglak ◽  
Rafał Kukawka ◽  
Piotr Lewandowski ◽  
Henryk Pospieszny

2013 ◽  
Vol 117 (46) ◽  
pp. 14372-14384 ◽  
Author(s):  
Ilya A. Shkrob ◽  
Timothy W. Marin ◽  
Huimin Luo ◽  
Sheng Dai

2005 ◽  
Vol 17 (17) ◽  
pp. 2142-2146 ◽  
Author(s):  
H. Xue ◽  
J. M. Shreeve

2014 ◽  
Vol 43 (20) ◽  
pp. 7171-7187 ◽  
Author(s):  
Bingwei Xin ◽  
Jingcheng Hao

Supported ionic liquids (SILs), which refer to ionic liquids (ILs) immobilized on supports, are among the most important derivatives of ILs.


Molecules ◽  
2020 ◽  
Vol 25 (11) ◽  
pp. 2705
Author(s):  
João Luís Ferreira da Silva ◽  
M. Fátima Minas da Piedade ◽  
Vânia André ◽  
Sofia Domingos ◽  
Inês C. B. Martins ◽  
...  

This short review presents and highlights the work performed by the Lisbon Group on the mechanochemical synthesis of active pharmaceutical ingredients (APIs) multicomponent compounds. Here, we show some of our most relevant contributions on the synthesis of supramolecular derivatives of well-known commercial used drugs and the corresponding improvement on their physicochemical properties. The study reflects, not only our pursuit of using crystal engineering principles for the search of supramolecular entities, but also our aim to correlate them with the desired properties. The work also covers our results on polymorphic screening and describes our proposed alternatives to induce and maintain specific polymorphic forms, and our approach to avoid polymorphism using APIs as ionic liquids. We want to stress that all the work was performed using mechanochemistry, a green advantageous synthetic technique.


Sign in / Sign up

Export Citation Format

Share Document