Rodent ultrasonic communication: Male prosocial 50-kHz ultrasonic vocalizations elicit social approach behavior in female rats (Rattus norvegicus).

The susceptibility of laboratory rats (Rattus norvegicus) to experimental inoculation with tachyzoites of Neospora caninum was examined. Groups of female rats were intramuscularly injected with 0, 2, or 4 mg of methylprednisolone acetate (MPA) 7 days prior to, and on the day of, subcutaneous inoculation with 0 or 1.5 × 105 tachyzoites. Clinical signs of disease or deaths did not occur in rats given nothing or only N. caninum tachyzoites. Rats given only 4 mg MPA failed to grow as well as rats given nothing or only N. caninum tachyzoites but were otherwise healthy. All of 20 rats given 4 mg MPA and tachyzoites died of hepatitis and pneumonia within 12 days postinoculation. Hepatic necrosis was the most striking lesion seen in these rats, and other milder lesions consisted of pneumonia, encephalitis, and myositis. The response of rats given 2 mg MPA and tachyzoites was less severe. Three of 20 rats died with encephalitis, myositis, hepatitis, and pancreatitis. Mild lesions, but no N. caninum tachyzoites, were seen in 3 of 14 rats inoculated only with tachyzoites. Rats given the 4 mg MPA treatment and inoculated with N. caninum tachyzoites appear to be suitable subjects for examining acute neosporosis and could be used in studies designed to examine treatment of acute disease.

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Touchscreen learning deficits and normal social approach behavior in the Shank3B model of Phelan–McDermid Syndrome and autism

Neuroscience ◽

10.1016/j.neuroscience.2016.05.016 ◽

2017 ◽

Vol 345 ◽

pp. 155-165 ◽

Cited By ~ 26

Author(s):

Nycole A. Copping ◽

Elizabeth L. Berg ◽

Gillian M. Foley ◽

Melanie D. Schaffler ◽

Beth L. Onaga ◽

...

Keyword(s):

Social Approach ◽

Learning Deficits ◽

Approach Behavior

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Improving the Quality of Oocytes of Old and Productive Ages White Rats (Rattus norvegicus) Using Pregnant Mare Serum Gonadotrophin

Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) ◽

10.20956/jrvi.v3i1.5627 ◽

2019 ◽

Vol 3 (1) ◽

Author(s):

Sultania A Suleman ◽

Andriyanto Andriyanto ◽

Aulia Andi Mustika ◽

Wasmen Manalu

Keyword(s):

Rattus Norvegicus ◽

Oocyte Quality ◽

The Other ◽

Female Rats ◽

Age Group ◽

White Rats ◽

Maze Test ◽

Swimming Test ◽

Pregnant Mare Serum Gonadotrophin

Abstract This study was conducted to improve the quality of oocytes in old-female rats by using pregnant mare serum gonadotrophin (PMSG). Female rats at productive age were used as a control. The experimental rats were injected with 4 doses of PMSG i.e., 0, 2.5, 5.0, and 10 IU PMSG. After 2 weeks of acclimation to the experimantal condition, the experimental rats were injected with PGF2α at a dose of 25µg/g BW two times with 2 days interval to synchronize estrous cycle. PMSG injections were conducted at the same time with the second PGF2α injection. After PMSG injection, the experimental rats were divided into two groups rats, i.e., rats without mating for masurement of oocyte qualities and rats mated for measurement of offspring qualities. Therefore, 16 experimental rats from each age group were sacrifized for maeasurement of oocyte qualities. The other 16 experimental rats for each age group were mated for measurement of offspring qualities. Parameters measured were hematological profile, uterine and ovarian weights, the qualities of oocytes, the qualities of the offsspring born by using swimming test and rat maze test. The collected data were analyzed by analysis of variance (ANOVA) and continued with Duncan test with a 95% confidence level. The data were analyzed using SSPS. The results showed that the improvement in the quality of oocytes in old female rats using the PMSG hormone in this study showed an increase in the quality of oocytes in old and productive age rats. The highest number of oocyte quality was found in rats of productive age (3.25) and significantly different (P< 0.05) from the other oocyte qualities. The quality of offspring born to old age and productive age rats injected with PMSG were improved. It was concluded that the improvement of oocyte quality by using PMSG also improves offspring qualities.

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Stimulus control of maternal responsiveness to Norway rat ( Rattus norvegicus) pup ultrasonic vocalizations.

Journal of Comparative Psychology ◽

10.1037/0735-7036.116.3.297 ◽

2002 ◽

Vol 116 (3) ◽

pp. 297-307 ◽

Cited By ~ 39

Author(s):

William J. Farrell ◽

Jeffrey R. Alberts

Keyword(s):

Stimulus Control ◽

Rattus Norvegicus ◽

Ultrasonic Vocalizations ◽

Maternal Responsiveness ◽

Norway Rat

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Maternal restraint stress during pregnancy negatively affects behaviors and antioxidant capacity of offspring rats (Rattus norvegicus)

Canadian Journal of Zoology ◽

10.1139/cjz-2017-0264 ◽

2018 ◽

Vol 96 (8) ◽

pp. 882-887 ◽

Cited By ~ 2

Author(s):

Chao Yin ◽

Guofu Wang ◽

Shixing Gao ◽

Yanping Huang ◽

Ruqian Zhao ◽

...

Keyword(s):

Antioxidant Capacity ◽

Soleus Muscle ◽

Rattus Norvegicus ◽

Biochemical Parameters ◽

Restraint Stress ◽

Gastrocnemius Muscle ◽

Female Offspring ◽

Female Rats ◽

Male Rats ◽

Biochemical Indices

This study evaluated the effect of maternal restraint stress during the gestation period on behaviors, biochemical parameters, and antioxidant capacities of offspring rats (Rattus norvegicus (Berkenhout,1769)) at weaning age. Behaviors, plasma biochemical indices, and antioxidant ability of the liver, soleus muscle, and gastrocnemius muscle of mother and (or) offspring rats were analyzed. Significant increases were found in the immobility and swinging behavior frequencies of offspring male rats; no difference was found in behaviors of female rats. The antioxidant indices including superoxide dismutase, nitric oxide synthase, and total antioxidant capacity in the soleus muscle of offspring male rats were significantly decreased in the restraint group. Female offspring rats showed significant lower glutathione and higher malondialdehyde levels in the gastrocnemius muscle and liver, respectively. No difference was found in the productive performance and plasma biochemical indices of maternal rats, nor in the biochemical parameters of the two groups of weaning rats. The results suggested that maternal chronic stresses negatively affected the behaviors and antioxidant abilities of offspring rats, and that these effects possibly have a greater impact on offspring male rats than on female rats.

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