Implementation of an HIV Rapid Testing/Linkage to Care Project Among Homeless Individuals

2014 ◽  
Author(s):  
Henry Anaya ◽  
Herschel Knapp ◽  
Magdalena Esquivel ◽  
Sophia F. Rumanes ◽  
Jaimi N. Butler ◽  
...  
2015 ◽  
Vol 20 (14) ◽  
Author(s):  
M J Belza ◽  
J Hoyos ◽  
S Fernández-Balbuena ◽  
A Diaz ◽  
M J Bravo ◽  
...  

We assess the added value of a multisite, street-based HIV rapid testing programme by comparing its results to pre-existing services and assessing its potential to reduce ongoing transmission. Between 2008 and 2011, 8,923 individuals underwent testing. We compare outcomes with those of a network of 20 sexually transmitted infections (STI)/HIV clinics (EPI-VIH) and the Spanish National HIV Surveillance System (SNHSS); evaluate whether good visibility prompts testing and assess whether it reaches under-tested populations. 89.2% of the new infections were in men who have sex with men (MSM) vs 78.0% in EPI-VIH and 56.0% in SNHSS. 83.6% of the MSM were linked to care and 20.9% had?<350 CD4 HIV prevalence was substantially lower than in EPI-VIH. 56.5% of the HIV-positive MSM tested because they happened to see the programme, 18.4% were previously untested and 26.3% had their last test ≥2 years ago. The programme provided linkage to care and early diagnosis mainly to MSM but attendees presented a lower HIV prevalence than EPI-VIH. From a cost perspective it would benefit from being implemented in locations highly frequented by MSM. Conversely, its good visibility led to reduced periods of undiagnosed infection in a high proportion of MSM who were not testing with the recommended frequency.


PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e80594 ◽  
Author(s):  
Huanmiao Xun ◽  
Dianmin Kang ◽  
Tao Huang ◽  
Yuesheng Qian ◽  
Xiufang Li ◽  
...  

2017 ◽  
Vol 20 ◽  
pp. 21780 ◽  
Author(s):  
Peter Bock ◽  
Comfort Phiri ◽  
Estelle Piwowar-Manning ◽  
Barry Kosloff ◽  
Nomtha Mandla ◽  
...  

Author(s):  
Maira Sohail ◽  
Emily Bess Levitan ◽  
Aadia Iftikhar Rana ◽  
Sonya Lynn Heath ◽  
Jeremiah Rastegar ◽  
...  

Estimating the population with undiagnosed HIV (PUHIV) is the most methodologically challenging aspect of evaluating 90-90-90 goals. The objective of this review is to discuss assumptions, strengths, and shortcomings of currently available methods of this estimation. Articles from 2000 to 2018 on methods to estimate PUHIV were reviewed. Back-calculation methods including CD4 depletion and test–retest use diagnosis CD4 count, or previous testing history to determine likely infection time thus, providing an estimate of PUHIV for previous years. Biomarker methods use immunoassays to differentiate recent from older infections. Statistical techniques treat HIV status as missing data and impute data for models of infection. Lastly, population surveys using HIV rapid testing most accurately calculates the current HIV prevalence. Although multiple methods exist to estimate the number of PUHIV, the appropriate method for future applications depends on multiple factors, namely data availability and population of interest.


Public Health ◽  
2017 ◽  
Vol 151 ◽  
pp. 23-26 ◽  
Author(s):  
I. Sangare ◽  
A. Jolivet ◽  
A. Adenis ◽  
L. Adriouch ◽  
M. Levy-Loeb ◽  
...  

2020 ◽  
Vol 45 (6) ◽  
pp. 1228-1235
Author(s):  
Shamaya Whitby ◽  
◽  
Amanda Smith ◽  
Rebecca Rossetti ◽  
Johanna Chapin-Bardales ◽  
...  

Abstract HIV rapid testing algorithms (RTAs) using any two orthogonal rapid tests (RTs) allow for on-site confirmation of infection. RTs vary in performance characteristics therefore the selection of RTs in an algorithm may affect identification of infection, particularly if acute. National HIV Behavioral Surveillance (NHBS) assessed RTAs among men who have sex with men recruited using anonymous venue-based sampling. Different algorithms were evaluated among participants who self-reported never having received a positive HIV test result prior to the interview. NHBS project areas performed sequential or parallel RTs using whole blood. Participants with at least one reactive RT were offered anonymous linkage to care and provided a dried blood spot (DBS) for testing at CDC. Discordant results (RT-1 reactive/RT-2 non-reactive) were tested at CDC with lab protocols modified for DBS. DBS were also tested for HIV-1 RNA (VL) and antiretroviral (ARV) drug levels. Of 6500 RTAs, 238 were RT-1 reactive; of those, 97.1% (231/238) had concordant results (RT-1/RT-2 reactive) and 2.9% (7/238) had discordant results. Five DBS associated with discordant results were available for confirmation at CDC. Four had non-reactive confirmatory test results that implied RT-1 false reactivity; one had ambiguous confirmatory test results which was non-reactive in further testing. Regardless of order and type of RT used, RTAs demonstrated high concordant results in the population surveyed. Additional laboratory testing on DBS following discordant results confirmed no infection. Implementing RTAs in the context of anonymous venue-based HIV testing could be an option when laboratory follow-up is not practicable.


2016 ◽  
Vol 17 (5) ◽  
pp. 722-730 ◽  
Author(s):  
Sonjia Kenya ◽  
Ikenna S. Okoro ◽  
Kiera Wallace ◽  
Michael Ricciardi ◽  
Olveen Carrasquillo ◽  
...  

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