India — stop looking down on international collaborations

Abstract Introduction Pooling population-based data from all national bariatric registries may provide international real-world evidence for outcomes that will help establish a universal standard of care, provided that the same variables and definitions are used. Therefore, this study aims to assess the concordance of variables across national registries to identify which outcomes can be used for international collaborations. Methods All 18 countries with a national bariatric registry who contributed to The International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) Global Registry report 2019 were requested to share their data dictionary by email. The primary outcome was the percentage of perfect agreement for variables by domain: patient, prior bariatric history, screening, operation, complication, and follow-up. Perfect agreement was defined as 100% concordance, meaning that the variable was registered with the same definition across all registries. Secondary outcomes were defined as variables having “substantial agreement” (75–99.9%) and “moderate agreement” (50–74.9%) across registries. Results Eleven registries responded and had a total of 2585 recorded variables that were grouped into 250 variables measuring the same concept. A total of 25 (10%) variables have a perfect agreement across all domains: 3 (18.75%) for the patient domain, 0 (0.0%) for prior bariatric history, 5 (8.2%) for screening, 6 (11.8%) for operation, 5 (8.8%) for complications, and 6 (11.8%) for follow-up. Furthermore, 28 (11.2%) variables have substantial agreement and 59 (23.6%) variables have moderate agreement across registries. Conclusion There is limited uniform agreement in variables across national bariatric registries. Further alignment and uniformity in collected variables are required to enable future international collaborations and comparison. Graphical abstract

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Commission 9: Instrumentation and Techniques: (Instrumentation et Techniques)

Transactions of the International Astronomical Union ◽

10.1017/s0251107x00003266 ◽

2000 ◽

Vol 24 (1) ◽

pp. 316-327

Author(s):

Ian S. McLean ◽

Ding-Qiang Su ◽

Thomas Armstrong ◽

Noah Brosch ◽

Martin Cullum ◽

...

Keyword(s):

Adaptive Optics ◽

Global Networks ◽

General Ground ◽

International Collaborations ◽

Long Time ◽

Robotic Telescopes ◽

New Instruments ◽

Innovative Techniques ◽

Full Operation

The last triennium, and coincidentally the last few years of the 20th century, has been a most remarkable time for Commission 9, and for astronomy in general. Ground-based astronomy in particular has received an enormous boost due to the arrival of an astonishing array of new telescopes, novel instruments and innovative techniques. For those of us closely involved in developing new observatories, instrumentation or detectors, the last few years have been rather hectic! As an astronomer with a long-time interest in the development of new instruments, what amazes me is the breadth of technology and the visionary scope of all these incredible new achievements. Many of the very large 8-10 meter class telescopes are now coming into full operation – yet, just as this is happening, numerous smaller “survey” telescopes are providing a wealth of new sources. Adaptive optics is being practiced at many sites and diffraction-limited imaging from the ground is now a reality. Several optical-IR interferometers are now working and more are coming along very soon. Detectors continue to get bigger and better, especially for the infrared, and instrumentation is increasingly more sophisticated, complex and efficient. Remote observing, robotic telescopes and global networks of telescopes are common, and international collaborations are larger and stronger than ever before.

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Prognostic Factors for Wilms Tumor Recurrence: A Review of the Literature

Cancers ◽

10.3390/cancers13133142 ◽

2021 ◽

Vol 13 (13) ◽

pp. 3142

Author(s):

Alissa Groenendijk ◽

Filippo Spreafico ◽

Ronald R. de Krijger ◽

Jarno Drost ◽

Jesper Brok ◽

...

Keyword(s):

Prognostic Factors ◽

Tumor Recurrence ◽

Wilms Tumor ◽

Clinicopathological Characteristics ◽

Copy Number Variations ◽

First Line ◽

Prognostic Variables ◽

Treatment Regimens ◽

International Collaborations ◽

Patients Experience

In high-income countries, the overall survival of children with Wilms tumors (WT) is ~90%. However, overall, 15% of patients experience tumor recurrence. The adverse prognostic factors currently used for risk stratification (advanced stage, high risk histology, and combined loss of heterozygosity at 1p and 16q in chemotherapy-naïve WTs) are present in only one third of these cases, and the significance of these factors is prone to change with advancing knowledge and improved treatment regimens. Therefore, we present a comprehensive, updated overview of the published prognostic variables for WT recurrence, ranging from patient-, tumor- and treatment-related characteristics to geographic and socioeconomic factors. Improved first-line treatment regimens based on clinicopathological characteristics and advancing knowledge on copy number variations unveil the importance of further investigating the significance of biological markers for WT recurrence in international collaborations.

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Papers from international collaborations have higher impact

Cortex ◽

10.1016/j.cortex.2014.03.003 ◽

2014 ◽

Vol 53 ◽

pp. A1-A3 ◽

Cited By ~ 2

Author(s):

Jennifer A. Foley ◽

Sergio Della Sala

Keyword(s):

International Collaborations

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Guidelines for Genetic Nomenclature and Community Governance for the Model Legume Medicago truncatula

Molecular Plant-Microbe Interactions ◽

10.1094/mpmi.2001.14.12.1364 ◽

2001 ◽

Vol 14 (12) ◽

pp. 1364-1367 ◽

Cited By ~ 14

Author(s):

Kathryn A. VandenBosch ◽

Julia Frugoli

Keyword(s):

Medicago Truncatula ◽

Rapid Growth ◽

Model System ◽

Gene Nomenclature ◽

Community Governance ◽

Model Legume ◽

The Past ◽

Genetic Nomenclature ◽

International Collaborations

At the 2nd Medicago meeting (a satellite of the 1999 IS-MPMI meeting in Amsterdam), investigators perceived a need for standardization of genetic nomenclature in Medicago truncatula, due to the rapid growth of research on this species in the past few years. Establishment of such standards grew out of discussions begun at this meeting and continued electronically throughout the M. truncatula community. The proposed standards presented here are the consensus results of those discussions. In addition to standards for gene nomenclature, a method for community governance and a website for cataloging gene names and submitting new ones are presented. The purpose of implementing these guidelines is to help maintain consistency in the literature, to avoid redundancy, to contribute to the accuracy of databases, and, in general, to aid the international collaborations that have made M. truncatula a model system for legume biology.

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Adrenocortical Carcinoma: Current Therapeutic State-of-the-Art

Journal of Oncology ◽

10.1155/2012/234726 ◽

2012 ◽

Vol 2012 ◽

pp. 1-11 ◽

Cited By ~ 14

Author(s):

Amir H. Lebastchi ◽

John W. Kunstman ◽

Tobias Carling

Keyword(s):

Adrenocortical Carcinoma ◽

Clinical Trial Design ◽

Staging System ◽

Rational Drug Design ◽

Proper Role ◽

Rational Drug ◽

International Collaborations ◽

Low Prevalence ◽

Made In

Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy that generally conveys a poor prognosis. Currently, surgical resection is considered the lone curative treatment modality. In addition, the low prevalence of ACC has limited effective clinical trial design to develop evidence-based approaches to ACC therapy. The proper role of radio- and chemotherapy treatment for ACC is still being defined. Similarly, the molecular pathogenesis of ACC remains to be fully characterized. Despite these challenges, progress has been made in several areas. After years of refinement, an internationally accepted staging system has been defined. International collaborations have facilitated increasingly robust clinical trials, especially regarding agent choice and patient selection for chemotherapeutics. Genetic array data and molecular profiling have identified new potential targets for rational drug design as well as potential tumor markers and predictors of therapeutic response. However, these advances have not yet been translated into a large outcomes benefit for ACC patients. In this paper, we summarize established therapy for ACC and highlight recent findings in the field that are impacting clinical practice.

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Perspectives on the active volcanoes of China

Geological Society London Special Publications ◽

10.1144/sp510-2021-87 ◽

2021 ◽

pp. SP510-2021-87

Author(s):

Jiandong Xu ◽

Clive Oppenheimer ◽

James O. S. Hammond ◽

Haiquan Wei

Keyword(s):

Hainan Island ◽

Special Volume ◽

Quarter Century ◽

The Past ◽

Special Publication ◽

Current State ◽

International Collaborations ◽

Comprehensive Survey ◽

Natural Laboratory ◽

Active Volcanoes

AbstractChina ishas a rich record of Holocene volcanism that is relatively little known outside the country. It is encountered in home to a number of volcanoes that have erupted in the Holocene. These range from large stratovolcanoes in the northeast, linked to subduction of the pPacific plate (e.g., Changbaishan); in , more diffuse volcanismsmaller volcanoes on the edges of the TibetTibetan margin, linked toassociated with the collision of India and AEurasia (e.g., Tengchong, Ashishan), and more isolated regions of volcanismcentres possibly linked topossibly resulting from mantle upwelling (e.g., volcanoes in Hainan island). This makes China a natural laboratory for studyingstudies of intraplate volcanism, yet the study of volcanology in China is young, with a significant increase in research only over the last 25 yearsand significant progress in understanding its nature and origins has been made over the past quarter century. To highlight recent advances and the current state of knowledge, thisHere, we introduce the first publication in English to provide a comprehensive survey of the state of knowledge and research highlights. special volume presents the first compilation of research on the active volcanoes of China in English. This first paper introduces the book, which coversAccordingly, we provide an overview of the dynamics, geology, geochemistry, volcanic histories and geophysical studies of the 14 volcanoesvolcanic areas that have erupted in theassociated with Holocene documented thus far. Our hope is that this special publication acts as The special publication represents a benchmark reference on the topic but, as importantly, we hope it will stimulatea resource to allow new, international collaborations to be developed to help understandaimed at deepening our understanding of the origins, history, hazards and associated risks from future eruptions of China's volcanoes.

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