scholarly journals Cardiac remodeling and diastolic dysfunction in DahlS.Z-Leprfa/Leprfa rats: a new animal model of metabolic syndrome

2011 ◽  
Vol 35 (2) ◽  
pp. 186-193 ◽  
Author(s):  
Tamayo Murase ◽  
Takuya Hattori ◽  
Masafumi Ohtake ◽  
Mayuna Abe ◽  
Yui Amakusa ◽  
...  
2010 ◽  
Vol 16 (9) ◽  
pp. S147
Author(s):  
Tamayo Murase ◽  
Takuya Hattori ◽  
Miwa Takatsu ◽  
Mayuna Abe ◽  
Yui Amakusa ◽  
...  

Hypertension ◽  
2013 ◽  
Vol 62 (5) ◽  
pp. 957-965 ◽  
Author(s):  
Miwa Takatsu ◽  
Chieko Nakashima ◽  
Keiji Takahashi ◽  
Tamayo Murase ◽  
Takuya Hattori ◽  
...  

2021 ◽  
Vol 45 (10) ◽  
Author(s):  
Pema Raj ◽  
Xavier L. Louis ◽  
Liping Yu ◽  
Yaw L. Siow ◽  
Miyoung Suh ◽  
...  

2016 ◽  
Vol 7 (8) ◽  
pp. 3390-3401 ◽  
Author(s):  
Damiana D. Rosa ◽  
Łukasz M. Grześkowiak ◽  
Célia L. L. F. Ferreira ◽  
Ana Carolina M. Fonseca ◽  
Sandra A. Reis ◽  
...  

Kefir supplementation in rats with induced metabolic syndrome was able to lower fasting glucose, fasting insulin levels, and reduce insulin resistance.


Lipids ◽  
2013 ◽  
Vol 48 (11) ◽  
pp. 1115-1134 ◽  
Author(s):  
Shizuyo Tanaka ◽  
Tohru Yamazaki ◽  
Satoshi Asano ◽  
Atsushi Mitsumoto ◽  
Daisuke Kobayashi ◽  
...  

2021 ◽  
Author(s):  
Kaushiki Kirty ◽  
Prabha Adhikari

Abstract Background :The purpose of the present study was to study the prevalence of metabolic syndrome in non diabetic patients of metabolic syndrome Materials and Methods: 100 patients of non diabetic metabolic syndrome were screened using 2-D Echocardiogram.Results: 34% of non diabetic patients of metabolic syndrome had diastolic dysfunction, with no association found between the components of metabolic syndrome and diastolic dysfunction. There was a strong correlation between a past history of hypertension and dyslipidemia with diastolic dysfunction.Conclusion: Our findings suggest that long standing metabolic syndrome is a risk factor for diastolic dysfunction, rather than short term elevation of the metabolic syndrome parameters. Also it is likely that Diabetes and Prediabetes itself is responsible for most of the diastolic dysfunction that is seen in metabolic syndrome


2020 ◽  
Vol 183 (11) ◽  
pp. 25-33
Author(s):  
S. N. Jadhav ◽  
V. G. Radchenko

The purpose of the study was to determine the frequency and nature of manifestations of left ventricular diastolic dysfunction in patients with non-alcoholic fatty liver disease with the background of metabolic syndrome (MS).Characteristics of patients and research methods: To solve this problem, 227 patients with MS (130 men and 97 women) were examined. The study was conducted in two phases. At the first stage, all patients with MS are divided into two groups: patients with NAFLD — 205 people and 22 — without liver damage. At the next stage, a group of NAFLD patients with left ventricular DD (n=136) (66.34%) (the main group) and patients with no DD (n=69) (33.66%) (the comparison group) were identified.Results of the study: the results of diagnostics, clinical and laboratory manifestations of left ventricular diastolic dysfunction in 136 patients with NAFLD on the background of metabolic syndrome are Presented. Significant factors of development and progression of diastolic dysfunction were identified, which include increased body weight and adipose tissue, insulin resistance, dyslipidemia, hyperuricemia, activity and stage of liver damage. According to the data of structural and functional changes in the myocardium, the role of diastolic dysfunction in the development of chronic heart failure in patients with NAFLD with manifestations of metabolic syndrome has been established.Conclusion: it was Found that the development of left ventricular diastolic dysfunction in patients with NAFLD is due to the morphofunctional state of the liver.


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