Short-term exposure to ambient ozone and stroke hospital admission: A case-crossover analysis

Abstract Background Long-term exposure to air pollution results in a high incidence of cardiovascular disease. Whether acute myocardial infarction is triggered by short-term exposure to air pollution is related to the average severity of air pollution in the area.DesignCase-crossover analysis.MethodsThis was a retrospective study based on hospital medical records. The study period was 2017-2018. Research data were collected from Taoyuan Hospital, which is located in a low-severity pollution area, and Taichung Hospital, which is in a high-severity pollution area, and the correlation between short-term air pollution exposure and acute myocardial infarction was analyzed.ResultsThe correlation between short-term exposure to ambient air pollutants and acute myocardial infarction was not significant for the cases collected from Taoyuan Hospital (PM2.5 OR: 1.006 & 95% CI: 0.995-1.017; PM10 OR: 0.996 & 95% CI: 0.988-1.003). However, for the cases collected from Taichung Hospital, short-term exposure to ambient PM2.5 (odds ratio: 1.021; 95% confidence interval: 1.002-1.040) and PM10 (odds ratio: 1.010; 95% confidence interval: 1.001-1.020) resulted in high incidence of acute myocardial infarction.ConclusionsShort-term pollutant exposure will increase the incidence of acute myocardial infarction based on the severity of regional air pollution. In addition to addressing traditional cardiovascular disease risk factors, the government must formulate relevant policies for reducing air pollution and thus the hazards to national health.

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Faculty Opinions recommendation of Atrial Fibrillation Burden and Short-Term Risk of Stroke: Case-Crossover Analysis of Continuously Recorded Heart Rhythm From Cardiac Electronic Implanted Devices.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725640831.793514215 ◽

2016 ◽

Author(s):

Scott Kasner

Keyword(s):

Atrial Fibrillation ◽

Heart Rhythm ◽

Short Term ◽

Case Crossover ◽

Crossover Analysis ◽

Atrial Fibrillation Burden ◽

Stroke Case ◽

Implanted Devices

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Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China

Respiratory Research ◽

10.1186/s12931-021-01731-x ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Zhan Ren ◽

Xingyuan Liu ◽

Tianyu Liu ◽

Dieyi Chen ◽

Kuizhuang Jiao ◽

...

Keyword(s):

Air Pollution ◽

Hospital Admission ◽

Hospital Admissions ◽

Conditional Logistic Regression ◽

Warm Season ◽

Central China ◽

Air Pollution Control ◽

Short Term ◽

Short Term Exposure ◽

Increased Risk

Abstract Background Positive associations between ambient PM2.5 and cardiorespiratory disease have been well demonstrated during the past decade. However, few studies have examined the adverse effects of PM2.5 based on an entire population of a megalopolis. In addition, most studies in China have used averaged data, which results in variations between monitoring and personal exposure values, creating an inherent and unavoidable type of measurement error. Methods This study was conducted in Wuhan, a megacity in central China with about 10.9 million people. Daily hospital admission records, from October 2016 to December 2018, were obtained from the Wuhan Information center of Health and Family Planning, which administrates all hospitals in Wuhan. Daily air pollution concentrations and weather variables in Wuhan during the study period were collected. We developed a land use regression model (LUR) to assess individual PM2.5 exposure. Time-stratified case-crossover design and conditional logistic regression models were adopted to estimate cardiorespiratory hospitalization risks associated with short-term exposure to PM2.5. We also conducted stratification analyses by age, sex, and season. Results A total of 2,806,115 hospital admissions records were collected during the study period, from which we identified 332,090 cardiovascular disease admissions and 159,365 respiratory disease admissions. Short-term exposure to PM2.5 was associated with an increased risk of a cardiorespiratory hospital admission. A 10 μg/m3 increase in PM2.5 (lag0–2 days) was associated with an increase in hospital admissions of 1.23% (95% CI 1.01–1.45%) and 1.95% (95% CI 1.63–2.27%) for cardiovascular and respiratory diseases, respectively. The elderly were at higher PM-induced risk. The associations appeared to be more evident in the cold season than in the warm season. Conclusions This study contributes evidence of short-term effects of PM2.5 on cardiorespiratory hospital admissions, which may be helpful for air pollution control and disease prevention in Wuhan.

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Association of Short-term Particulate Matter Exposure with Suicide Death Among Major Depressive Disorder Patients: A Time-Stratified Case-Crossover Analysis

10.21203/rs.3.rs-290077/v1 ◽

2021 ◽

Author(s):

In Young Hwang ◽

Daein Choi ◽

Jihoon Andrew Kim ◽

Seulggie Choi ◽

Jooyoung Chang ◽

...

Keyword(s):

Major Depressive Disorder ◽

Particulate Matter ◽

Depressive Disorder ◽

Short Term ◽

Major Depressive ◽

Suicide Death ◽

Case Crossover ◽

Crossover Analysis ◽

High Level ◽

Particulate Matter Exposure

Abstract Objective: There is growing evidence that suggests a potential association between particulate matter (PM) and suicide. However, it is unclear that PM exposure and suicide death among major depressive disorder (MDD) patients, a high-risk group for suicide.Methods: We investigated the risk of suicide among 1,046,169 newly-diagnosed MDD patients from 2004 to 2015 within the Korean National Health Insurance Service (NHIS) database. We identified 3,372 suicide cases from January 1, 2015, to December 31, 2017, within the death statistics database of the Korean National Statistical Office. PMs with diameter less than 2.5 μm (PM2.5), less than 10 μm (PM10), and 2.5 μm to 10 μm (PM2.5-10) were considered, which were provided from the National Ambient Air Monitoring System in South Korea. Time-stratified case-crossover analysis was performed to investigate the association of particulate matter exposure to suicide events.Results: The risk of suicide was significantly high upon the high level of exposure to PM2.5-10, PM10 on lag 1 (p for trend = 0.044, 0.035, respectively). A similar association was observed in the multi-day lag model (lag 0-3). Increasing exposure to PM 2.5 was not associated with increased suicide risk.Conclusions: Short-term exposure to a high level of PM2.5-10 and PM10 was associated with an elevated risk for suicide among MDD patients, while PM2.5 did not. There is a clear dose-response relationship between short-term coarse particle exposures with suicide death among Major Depressive Disorder patients. This result will be used as an essential basis for consideration when establishing an air pollution alarm system and implementing a suicide prevention program for reducing adverse health outcomes by PM.

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