scholarly journals Intake of high-fructose corn syrup sweetened soft drinks, fruit drinks and apple juice is associated with prevalent arthritis in US adults, aged 20–30 years

2016 ◽  
Vol 6 (3) ◽  
pp. e199-e199 ◽  
Author(s):  
L R DeChristopher ◽  
J Uribarri ◽  
K L Tucker
Keyword(s):  
Apple Juice ◽  
Soft Drinks ◽  
High Fructose Corn Syrup ◽  
Corn Syrup ◽  
High Fructose

scholarly journals Identification of Hydrolyzed Inulin Syrup and High-Fructose Corn Syrup in Apple Juice by Capillary Gas Chromatography PVM 4:1999

2001 ◽  
Vol 84 (2) ◽  
pp. 486-492 ◽  
Author(s):  
Nicholas H Low ◽  
Michael A McLaughlin ◽  
Samuel W Page ◽  
Benjamin J Canas ◽  
Allan R Brause ◽  
...  
Keyword(s):  
Apple Juice ◽  
Test Sample ◽  
High Fructose Corn Syrup ◽  
Corn Syrup ◽  
Flame Ionization ◽  
High Fructose ◽  
Freeze Dried ◽  
Juice Concentrate ◽  
Trimethylsilyl Derivatives ◽  
Brix Value

Abstract A peer-verified, gas chromatographic (GC) method is presented for the identification of hydrolyzed inulin syrup (HIS) and high-fructose corn syrup (HFCS) in apple juice. The procedure involves determining the Brix value of the apple juice or apple juice concentrate and preparing a dilution of the test sample to 5.5° Brix. A 100 μL aliquot of the 5.5° Brix test solution is then freeze-dried in a GC autosampler vial. The sugars in the freeze-dried residue are converted to trimethylsilyl derivatives, by the addition of an appropriate silylation reagent, and the vial is heated at 75°C for 30 min. After derivatization, the solution is introduced into a gas chromatograph where the analytes are separated on a 30 m, 0.25 mm id DB-5 column. The method can use hydrogen, helium, or nitrogen as the carrier gas. The analytes and marker compounds are measured by use of a flame ionization detector. Commercial apple juice concentrates were diluted with one of the 2 syrups at 2 levels. Dilution was ascertained by the presence of retrograde sugar markers found in the 2 sugar syrups. All 3 laboratories involved in the study were able to identify the correct diluent in the blind, randomly coded, apple juice test portions. The levels of dilution in the test portions were 0, 6.9% (HIS), 16.0% (HIS), 8.1% (HFCS), and 17.0% (HFCS). No false positive results were reported. Quantitative conclusions can be drawn when the same syrup is used for dilution and as a reference standard.

scholarly journals Excess free fructose, high-fructose corn syrup and adult asthma: the Framingham Offspring Cohort

2018 ◽  
Vol 119 (10) ◽  
pp. 1157-1167 ◽  
Author(s):  
Luanne R. DeChristopher ◽  
Katherine L. Tucker
Keyword(s):  
Orange Juice ◽  
Apple Juice ◽  
Asthma Prevalence ◽  
High Fructose Corn Syrup ◽  
Offspring Cohort ◽  
Corn Syrup ◽  
Fructose Malabsorption ◽  
Diet Soda ◽  
Asthma Risk ◽  
High Fructose

AbstractThere is growing evidence that intakes of high-fructose corn syrup (HFCS), HFCS-sweetened soda, fruit drinks and apple juice – a high-fructose 100 % juice – are associated with asthma, possibly because of the high fructose:glucose ratios and underlying fructose malabsorption, which may contribute to enteral formation of pro-inflammatory advanced glycation end products, which bind receptors that are mediators of asthma. Cox proportional hazards models were used to assess associations between intakes of these beverages and asthma risk, with data from the Framingham Offspring Cohort. Diet soda and orange juice – a 100 % juice with a 1:1 fructose:glucose ratio – were included for comparison. Increasing intake of any combination of HFCS-sweetened soda, fruit drinks and apple juice was significantly associated with progressively higher asthma risk, plateauing at 5–7 times/weekv. never/seldom, independent of potential confounders (hazard ratio 1·91,P<0·001). About once a day consumers of HFCS-sweetened soda had a 49 % higher risk (P<0·011), moderate apple juice consumers (2–4 times/week) had a 61 % higher risk (P<0·007) and moderate fruit drink consumers had a 58 % higher risk (P<0·009), as compared with never/seldom consumers. There were no associations with diet soda/orange juice. These associations are possibly because of the high fructose:glucose ratios, and fructose malabsorption. Recommendations to reduce consumption may be inadequate to address asthma risk, as associations are evident even with moderate intake of these beverages, including apple juice – a 100 % juice. The juice reductions in the US Special Supplemental Nutrition Program for Women, Infants, and Children in 2009, and the plateauing/decreasing asthma prevalence (2010–2013), particularly among non-Hispanic black children, may be related. Further research regarding the consequences of fructose malabsorption is needed.

scholarly journals Intakes of apple juice, fruit drinks and soda are associated with prevalent asthma in US children aged 2–9 years

2015 ◽  
Vol 19 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Luanne Robalo DeChristopher ◽  
Jaime Uribarri ◽  
Katherine L Tucker
Keyword(s):  
Advanced Glycation End Products ◽  
Apple Juice ◽  
High Fructose Corn Syrup ◽  
Advanced Glycation ◽  
Corn Syrup ◽  
High Fructose ◽  
Glycation End Products ◽  
End Products ◽  
Asthma In Children ◽  
Us Children

AbstractObjectiveHigh soft drink consumption has been linked with asthma. Anecdotal evidence links high-fructose corn syrup with asthma. The receptor of advanced glycation end products (RAGE) has emerged as a mediator of asthma. The objectives of the present study were to: (i) assess the correlation between intake of beverages containing excess free fructose (EFF beverages) and asthma in children; and (ii) epidemiologically test the mechanistic hypothesis that intake of high EFF beverages, such as apple juice or beverages sweetened with high-fructose corn syrup, is associated with increased risk of asthma. This hypothesis is based on the possible effect of increases in the in situ intestinal formation of advanced glycation end products (enFruAGE) with EFF, which may be absorbed and play a role in RAGE-mediated asthma.DesignWe examined cross-sectional associations between beverage intake and self-reported current or history of asthma. Exposure variables were EFF beverages, including apple juice (AJ), non-diet soft drinks (ndSD) and fruit drinks (FD). Orange juice (OJ), not an EFF beverage, was included as a comparison. Rao–Scott χ2 analysis was used for prevalence differences and logistic regression for associations, adjusted for age, sex, race/ethnicity, BMI and total energy intake.SettingData are from the National Health and Nutrition Examination Survey 2003–2006, a nationally representative survey.SubjectsUS children (n 1961) aged 2–9 years with complete responses on the dietary frequency questionnaire.ResultsIntakes of EFF beverages were significantly associated with asthma in 2–9-year-olds. Adjusted odds of asthma in children consuming EFF beverages ≥5 times/week was more than five times that in children consuming these beverages ≤1 time/month (OR=5·29, P=0·012). Children consuming AJ ≥5 times/week v. ≤1 time/month, adjusted for the other beverages, were more than twice as likely to have asthma (OR=2·43, P=0·035). In contrast, there was a tendency for OJ to be protective.ConclusionsThese results support the hypothesis that intake of high EFF beverages, including AJ and beverages sweetened with high-fructose corn syrup, is associated with asthma in children aged 2–9 years. Results support the mechanistic hypothesis that enFruAGE may be an overlooked contributor to asthma in children. Longitudinal studies are needed to provide evidence of causal association.

scholarly journals EXPLORING THE EFFECTS OF CONSUMERS’ NUTRITIONAL KNOWLEDGE AND INFORMATION INTEREST ON THE ACCEPTANCE OF ARTIFICIAL SWEETENER USAGE IN SOFT DRINKS

2019 ◽  
pp. 33-44 ◽  
Author(s):  
Yusuf Arslan
Keyword(s):  
Soft Drink ◽  
Food Additives ◽  
Well Being ◽  
Soft Drinks ◽  
Artificial Sweetener ◽  
High Fructose Corn Syrup ◽  
Nutritional Knowledge ◽  
Corn Syrup ◽  
The Public ◽  
High Fructose

Together with the increasing health awareness levels of consumers’, artificial food additives have been highly criticized by the public. However, these kinds of sweeteners are still being used widely all over the world. One of the sectors that prefer mostly these kinds of sweeteners is the soft drink industry. High fructose corn syrup, which has been associated with serious health problems recently, is one of these additives which is highly preferred in the soft drink industry. Upon examining the situation, it is understood that there is a conflict between the implementations of the soft drink industry and consumer attitudes towards them. However, it is seen that the consumers’ perspective is not clarified enough empirically in terms of this issue. This means that the players of the soft drink industry have a lack of insight in terms of consumer thoughts and attitudes regarding artificial sweetener usage in soft drinks. Owing to this research gap in the literature and the importance of the subject in terms of consumer well-being, this study aims to explore the antecedents for the acceptance of high fructose corn syrup usage in soft drinks. To reach this aim, four research questions represented to understand how frequent consumers prefer soft drinks containing high fructose corn syrup, to reveal consumers’ attitudes and acceptance towards high fructose corn syrup and to understand how nutritional knowledge and nutritional information interest affect consumers’ acceptance specifically on high fructose corn syrup usage in soft drinks. To answer these questions, a structured survey was developed and conducted on 888 soft drink consumers who are aware of high fructose corn syrup in soft drinks as an additive

scholarly journals Excessive Intake of High-Fructose Corn Syrup Drinks Induces Impaired Glucose Tolerance

Biomedicines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 541
Author(s):  
Hidemi Hattori ◽  
Yuma Hanai ◽  
Yuto Oshima ◽  
Hiroaki Kataoka ◽  
Nozomu Eto
Keyword(s):  
Insulin Secretion ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Caloric Intake ◽  
Soft Drinks ◽  
High Fructose Corn Syrup ◽  
Corn Syrup ◽  
High Fructose ◽  
Excessive Consumption ◽  
Excessive Intake

The number of patients with diabetes was approximately 463 million worldwide in 2019, with almost 57.6% of this population concentrated in Asia. Asians often develop type 2 diabetes (T2D), even if they are underweight and consume a smaller amount of food. Soft drinks contain large amounts of sweeteners, such as high-fructose corn syrup (HFCS). Excessive intake of HFCS drinks is considered to be one of the causes of T2D. In the present study, we investigated the effect of excessive consumption of HFCS–water on glucose tolerance and obesity under conditions of controlled caloric intake using a mouse model. Three-week-old male ICR mice were divided into two groups and given free access to 10% HFCS–water or deionized water. The caloric intake was adjusted to be the same in both groups using a standard rodent diet. The excess HFCS–water intake did not lead to obesity, but led to impaired glucose tolerance (IGT) due to insulin-secretion defect. It affected glucose and fructose metabolism; for example, it decreased the expression of glucokinases, ketohexokinase, and glucose transporter 2 in the pancreas. These results suggest that excessive consumption of HFCS drinks, such as soft drinks, without a proper diet, induces nonobese IGT due to insulin-secretion defect.

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