Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives

2021 ◽  
Author(s):  
Anselm F. L. Schneider ◽  
Marina Kithil ◽  
M. Cristina Cardoso ◽  
Martin Lehmann ◽  
Christian P. R. Hackenberger
Keyword(s):  
Cell Surface ◽  
Cellular Uptake ◽  
Cell Penetrating Peptide ◽  
Reactive Cell ◽  
Cell Penetrating

Tat(48-60) peptide amino acid sequence is not unique in its cell penetrating properties and cell-surface glycosaminoglycans inhibit its cellular uptake

2012 ◽  
Vol 158 (2) ◽  
pp. 277-285 ◽  
Author(s):  
Astrid Subrizi ◽  
Eva Tuominen ◽  
Alex Bunker ◽  
Tomasz Róg ◽  
Maxim Antopolsky ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Cell Surface ◽  
Cellular Uptake ◽  
Cell Penetrating

scholarly journals A comparison of acyl-moieties for noncovalent functionalization of PLGA and PEG-PLGA nanoparticles with a cell-penetrating peptide

RSC Advances ◽  
2021 ◽  
Vol 11 (57) ◽  
pp. 36116-36124
Author(s):  
Omar Paulino da Silva Filho ◽  
Muhanad Ali ◽  
Rike Nabbefeld ◽  
Daniel Primavessy ◽  
Petra H. Bovee-Geurts ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Plga Nanoparticles ◽  
Cell Penetrating Peptides ◽  
Cell Penetrating Peptide ◽  
Noncovalent Functionalization ◽  
Cell Penetrating ◽  
A Cell

Noncovalent functionalization with acylated cell-penetrating peptides achieves an efficient cellular uptake of PLGA and PEG-PLGA nanoparticles.

Lipid–Cell-Penetrating-Peptide Conjugates as Effective Delivery Systems

Synlett ◽  
2017 ◽  
Vol 28 (15) ◽  
pp. 1897-1900
Author(s):  
Zi-Gang Li ◽  
Yan-Hong Jiang ◽  
Hui Zhao ◽  
Yuan Tian
Keyword(s):  
Cellular Uptake ◽  
Biological Research ◽  
Cell Penetrating Peptide ◽  
Peptide Conjugates ◽  
Cellular Toxicity ◽  
Wide Range ◽  
Cell Penetrating ◽  
Effective Delivery ◽  
Cellular Permeability ◽  
Small Molecule Therapeutics

A lipid–cell-penetrating-peptide (CPP) conjugate was designed to deliver cargoes with poor cellular permeability, including peptides or small-molecule therapeutics, into cells. The lipid–CPP conjugate facilitated the cellular uptake of cargoes noncovalently through an ATP-dependent micropinocytosis mechanism. This delivery system is simple, efficient, has minimal cellular toxicity, and might be useful in a wide range of biological research.

The influence of cell penetrating peptide branching on cellular uptake of QDs

2016 ◽  
Author(s):  
Joyce Breger ◽  
James Delehanty ◽  
Kimihiro Susumu ◽  
George Anderson ◽  
Markus Muttenhaler ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating
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