scholarly journals Multi-modal magnetic resonance imaging in a mouse model of concussion

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Xuan Vinh To ◽  
Fatima A. Nasrallah
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Data Collection ◽  
Mouse Model ◽  
Meta Analysis ◽  
Data Repository ◽  
Resonance Imaging ◽  
Loss Of Righting Reflex ◽  
Post Impact ◽  
Magnetic Resonance Imaging Mri

AbstractThis data collection contains Magnetic Resonance Imaging (MRI) data, including structural, diffusion, stimulus-evoked, and resting-state functional MRI and behavioural assessment results, including acute post-impact Loss-of-Righting Reflex time and acute, subacute, and longer-term Neural Severity Score, and Open Field Behaviour obtained from a mouse model of concussion. Four cohorts with 43 3–4 months old male mice in total were used: Sham (n = 14, n = 6 day 2, n = 3 day 7, n = 5 day 14), concussion day 2 (CON 2; n = 9), concussion day 7 (CON 7; n = 10), concussion day 14 (CON 14; n = 10). The data collection contains the aforementioned MRI data in compressed NIFTI format, data sheets on animal’s backgrounds and behavioural outcomes and is made publicly available from a data repository. The available data are intended to facility cross-study comparisons, meta-analysis, and science reproducibility.

scholarly journals Global hippocampal atrophy in major depressive disorder: a meta-analysis of magnetic resonance imaging studies

2018 ◽  
Vol 40 (4) ◽  
pp. 369-378 ◽  
Author(s):  
Marcelo Antônio Oliveira Santos ◽  
Lucas Soares Bezerra ◽  
Ana Rita Marinho Ribeiro Carvalho ◽  
Alessandra Mertens Brainer-Lima
Keyword(s):  
Magnetic Resonance Imaging ◽  
Major Depressive Disorder ◽  
Magnetic Resonance ◽  
Depressive Disorder ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Hippocampal Atrophy ◽  
Resonance Imaging ◽  
Major Depressive ◽  
Magnetic Resonance Imaging Mri

Abstract Introduction: Major depressive disorder (MDD), an incapacitating mental disorder, is characterized by episodes of at least 2 weeks of apparent changes in mood, cognition, and neurovegetative functions. Many neuroimaging studies using magnetic resonance imaging (MRI) have examined morphometric changes in patients with MDD, but the results are not conclusive. This study aims to review the literature and perform a meta-analysis on hippocampal volume (HcV) in patients with MDD. Methods: Studies on HcV in patients with MDD diagnosis were identified from major databases (MEDLINE, EMBASE, The Cochrane Library, Scopus, PsycINFO, and SciELO) using the search terms depression, major depressive disorder, MDD, unipolar, magnetic resonance imaging, MRI, and hippocampus. Results: A meta-analysis of 29 studies fulfilling specific criteria was performed. The sample included 1327 patients and 1004 healthy participants. The studies were highly heterogeneous with respect to age, sex, age of onset, and average illness duration. However, the pooled effect size of depression was significant in both hippocampi. MDD was associated with right (-0.43; 95% confidence interval [95%CI] −0.66 to −0.21) and left (-0.40; 95%CI −0.66 to −0.15) hippocampal atrophy. Conclusions: MDD seems to be associated with global HcV atrophy. Larger longitudinal follow-up studies designed to analyze the influence of sociodemographic variables on this relationship are required to yield better evidence about this topic.

M1224 Accuracy of Magnetic Resonance Imaging (MRI) for the Diagnosis of Crohn S Disease (CD): A Systematic Review and Meta-Analysis

2010 ◽  
Vol 138 (5) ◽  
pp. S-358
Author(s):  
Maria Chaparro ◽  
Blanca Martínez de Guereñu ◽  
Jordi Rimola ◽  
Julian Panes ◽  
Javier P. Gisbert
Keyword(s):  
Magnetic Resonance Imaging ◽  
Systematic Review ◽  
Magnetic Resonance ◽  
Meta Analysis ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri
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