scholarly journals Natural bladder filling alters resting brain function at multiple spatial scales: a proof-of-concept MAPP Network Neuroimaging Study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ishtiaq Mawla ◽  
Andrew Schrepf ◽  
Eric Ichesco ◽  
Steven E. Harte ◽  
David J. Klumpp ◽  
...  
Keyword(s):  
Brain Function ◽  
Spatial Scales ◽  
Self Report ◽  
High Rate ◽  
Research Network ◽  
Brain Response ◽  
Specific Stimulus ◽  
Bladder Filling ◽  
Multiple Spatial Scales ◽  
Urinary Urge

AbstractNeural circuitry regulating urine storage in humans has been largely inferred from fMRI during urodynamic studies driven by catheter infusion of fluid into the bladder. However, urodynamic testing may be confounded by artificially filling the bladder repeatedly at a high rate and examining associated time-locked changes in fMRI signals. Here we describe and test a more ecologically-valid paradigm to study the brain response to bladder filling by (1) filling the bladder naturally with oral water ingestion, (2) examining resting state fMRI (rs-fMRI) which is more natural since it is not linked with a specific stimulus, and (3) relating rs-fMRI measures to self-report (urinary urge) and physiologic measures (voided volume). To establish appropriate controls and analyses for future clinical studies, here we analyze data collected from healthy individuals (N = 62) as part of the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. Participants orally ingested approximately 350 mL of water, and had a 10 min “fuller bladder” rs-fMRI scan approximately 1 h later. A second 10 min “empty bladder” rs-fMRI scan was conducted immediately following micturition. We examined multiple spatial scales of brain function, including local activity, circuits, and networks. We found changes in brain function distributed across micturition loci (e.g., subregions of the salience, sensorimotor, and default networks) that were significantly related to the stimulus (volume) and response (urinary urge). Based on our results, this paradigm can be applied in the future to study the neurobiological underpinnings of urologic conditions.

Inhibition of coral settlement at multiple spatial scales by a pervasive algal competitor

2019 ◽  
Vol 612 ◽  
pp. 29-42 ◽  
Author(s):  
NR Evensen ◽  
C Doropoulos ◽  
KM Morrow ◽  
CA Motti ◽  
PJ Mumby
Keyword(s):  
Spatial Scales ◽  
Coral Settlement ◽  
Multiple Spatial Scales

scholarly journals Risk Behaviours Associated with Dating and Relationship Violence among 11–16 Year Olds in Wales: Results from the 2019 Student Health and Wellbeing Survey

2021 ◽  
Vol 18 (3) ◽  
pp. 1192
Author(s):  
Danielle V. R. Couturiaux ◽  
Honor Young ◽  
Rebecca E. Anthony ◽  
Nicholas Page ◽  
Emily Lowthian ◽  
...  
Keyword(s):  
Peer Relationships ◽  
School Health ◽  
Risk Behaviour ◽  
Self Report ◽  
Research Network ◽  
Student Health ◽  
Relationship Violence ◽  
Risk Behaviours ◽  
Cross Sectional ◽  
Logistic Regression Models

(1) Background: This study examines the associations between risk behaviours and adolescent emotional and physical dating and relationship violence (DRV) victimisation and perpetration, and how these vary by gender. The risk behaviours explored include bullying, cyberbullying, sexting, alcohol, and cannabis use; (2) Methods: Cross-sectional self-report data from the School Health Research Network (SHRN) 2019 Student Health Wellbeing (SHW) survey of 48,397 students aged 11–16 from 149 schools across Wales were analysed using single and multiple-behaviour logistic regression models to explore the associations between each risk behaviour and emotional and physical DRV victimisation and perpetration; (3) Results: Bivariate analyses revealed a statistically significant association between DRV and all risk behaviours. In multivariate analyses, students who reported bullying, cyberbullying, sexting, and substance use, compared to those that had not, had significantly higher odds of experiencing and perpetrating emotional and physical DRV; and (4) Conclusions: Future studies on DRV should consider a mixed-methods approach to explore the context in which DRV and risk behaviours interrelate. Results from this study indicate the possibility that prevention and intervention programmes in school settings that seek to develop healthy school environments and peer-to-peer relationships, could inadvertently reduce the occurrence of future DRV and associated risk behaviours.

Assessment of clogging in constructed wetlands by saturated hydraulic conductivity measurements

2019 ◽  
Vol 79 (2) ◽  
pp. 314-322 ◽  
Author(s):  
F. Licciardello ◽  
R. Aiello ◽  
V. Alagna ◽  
M. Iovino ◽  
D. Ventura ◽  
...  
Keyword(s):  
Sensitivity Analysis ◽  
Hydraulic Conductivity ◽  
Constructed Wetlands ◽  
Spatial Scales ◽  
Pilot Scale ◽  
Laboratory Scale ◽  
Test Method ◽  
Conductivity Measurements ◽  
Multiple Spatial Scales ◽  
Ks Values

Abstract This study aims at defining a methodology to evaluate Ks reductions of gravel material constituting constructed wetland (CW) bed matrices. Several schemes and equations for the Lefranc's test were compared by using different gravel sizes and at multiple spatial scales. The falling-head test method was implemented by using two steel permeameters: one impervious (IMP) and one pervious (P) on one side. At laboratory scale, mean K values for a small size gravel (8–15 × 10−2 m) measured by the IMP and the P permeameters were equal to 19,466 m/d and 30,662 m/d, respectively. Mean Ks values for a big size gravel (10–25 × 10−2 m) measured by the IMP and the P permeameters were equal to 12,135 m/d and 20,866 m/d, respectively. Comparison of Ks values obtained by the two permeameters at laboratory scale as well as a sensitivity analysis and a calibration, lead to the modification of the standpipe equation, to evaluate also the temporal variation of the horizontal Ks. In particular, both permeameters allow the evaluation of the Ks decreasing after 4 years-operation and 1–1.5 years' operation of the plants at full scale (filled with the small size gravel) and at pilot scale (filled with the big size gravel), respectively.

scholarly journals FORMULATION OF THE HEAT CONDUCTION EQUATION FOR HETEROGENEOUS MEDIA WITH MULTIPLE SPATIAL SCALES USING REITERATED HOMOGENIZATION

2016 ◽  
Vol 15 (1) ◽  
pp. 96
Author(s):  
E. Iglesias-Rodríguez ◽  
M. E. Cruz ◽  
J. Bravo-Castillero ◽  
R. Guinovart-Díaz ◽  
R. Rodríguez-Ramos ◽  
...  
Keyword(s):  
Heat Conduction ◽  
Small Parameter ◽  
Heat Conduction Equation ◽  
Heterogeneous Media ◽  
Spatial Scales ◽  
Conduction Equation ◽  
Small Scale ◽  
Multiple Spatial Scales ◽  
Effective Coefficients ◽  
Reiterated Homogenization

Heterogeneous media with multiple spatial scales are finding increased importance in engineering. An example might be a large scale, otherwise homogeneous medium filled with dispersed small-scale particles that form aggregate structures at an intermediate scale. The objective in this paper is to formulate the strong-form Fourier heat conduction equation for such media using the method of reiterated homogenization. The phases are assumed to have a perfect thermal contact at the interface. The ratio of two successive length scales of the medium is a constant small parameter ε. The method is an up-scaling procedure that writes the temperature field as an asymptotic multiple-scale expansion in powers of the small parameter ε . The technique leads to two pairs of local and homogenized equations, linked by effective coefficients. In this manner the medium behavior at the smallest scales is seen to affect the macroscale behavior, which is the main interest in engineering. To facilitate the physical understanding of the formulation, an analytical solution is obtained for the heat conduction equation in a functionally graded material (FGM). The approach presented here may serve as a basis for future efforts to numerically compute effective properties of heterogeneous media with multiple spatial scales.

Applying systematic conservation planning to improve the allocation of restoration actions at multiple spatial scales

2021 ◽  
Author(s):  
Ben L. Gilby ◽  
Andrew D. Olds ◽  
Christopher J. Brown ◽  
Rod M. Connolly ◽  
Christopher J. Henderson ◽  
...  
Keyword(s):  
Conservation Planning ◽  
Spatial Scales ◽  
Systematic Conservation Planning ◽  
Multiple Spatial Scales

Bird research in the ACWERN lab at the Faculty of Forestry and Environmental Management, University of New Brunswick

2008 ◽  
Vol 84 (4) ◽  
pp. 548-552 ◽  
Author(s):  
Antony W Diamond
Keyword(s):  
New Brunswick ◽  
Forest Cover ◽  
Spatial Scales ◽  
Breeding Habitat ◽  
Research Network ◽  
Spatial Effects ◽  
Winter Habitat ◽  
Forested Landscapes ◽  
Carry Over ◽  
Species Specific

Research on forest bird ecology in the ACWERN (Atlantic Cooperative Wildlife Ecology Research Network) lab at the University of New Brunswick, Fredericton, since 1995 has focused on assessing the relative contributions of habitat quality at large (“landscape”) and small (“local” or “stand”) spatial scales. To do so we had to develop methods for assessing key demographic components of fitness (productivity and survival) at large spatial scales. The large extent of forest cover in the Maritimes contrasts with regions where such work has traditionally been carried out, in which forest is clearly fragmented by agriculture or residential development. Our main findings are that spatial effects in highly forested landscapes can often be detected only by using species-specific habitat models, rather than broader categories such as “mature” or “softwood”, that Blackburnian Warblers (Dendroica fusca) are effective indicators of mixedwood forest but define it differently than forest managers do, and that cavity nesters (e.g., woodpeckers) may require different habitat components for nesting and feeding and so cannot be managed for solely on the basis of providing snags for nesting. Our focus has shifted recently to intensive studies on a species at risk, Bicknell's Thrush (Catharus bicknelli), which in New Brunswick breeds in man-made regenerating softwood forest stands, and assessing its response both to precommercial thinning of the breeding habitat and to effects carrying over from the winter habitat in the Caribbean. Key words: landscape effects, thresholds, survival, productivity, fitness, carry-over, habitat, fragmentation

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