scholarly journals Mapping three-dimensional temperature in microfluidic chip

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Jinbo Wu ◽  
Tsz Yan Kwok ◽  
Xiaolin Li ◽  
Wenbin Cao ◽  
Yu Wang ◽  
...  
Keyword(s):  
Microfluidic Chip ◽  
Three Dimensional

scholarly journals Adsorption and isolation of nucleic acids on cellulose magnetic beads using a three-dimensional printed microfluidic chip

2015 ◽  
Vol 9 (6) ◽  
pp. 064118 ◽  
Author(s):  
Lei Zhang ◽  
Rachel N. Deraney ◽  
Anubhav Tripathi
Keyword(s):  
Nucleic Acids ◽  
Microfluidic Chip ◽  
Magnetic Beads ◽  
Three Dimensional

Maskless Gray Scale Lithography and its 3D Microfluidic Applications

2011 ◽  
Vol 23 (3) ◽  
pp. 426-433 ◽  
Author(s):  
Yoko Yamanishi ◽  
◽  
Takuma Nakano ◽  
Yu Sawada ◽  
Kazuyoshi Itoga ◽  
...  
Keyword(s):  
Cross Section ◽  
Mechanical Stimulation ◽  
Microfluidic Chip ◽  
Zona Pellucida ◽  
Three Dimensional ◽  
Cell Manipulation ◽  
The Novel ◽  
Gray Scale

This paper presents the novel three-dimensional fabrication using maskless exposure equipment and threedimensional (3D) microfluidic cell manipulation uses grayscale data to directly control the exposed photoresist height without using a mask. The 3D microchannel and microvalve were fabricated simply using lowcost exposure and height ranging from 0 to 200 µm. The 3D microvalve prevents liquid leakage when the membrane is closed – difficult to do using conventional 2D photolithography. We removed the oocyte zona pellucida passing through the 3D microchannel whose cross-section is gradually restricted along the path to provide mechanical stimulation omnidirectionally on the oocyte surface. The microfluidic chip may contribute to make high peeled-oocyte throughput effective without damaging the oocytes.

A three-dimensional cell-laden microfluidic chip for in vitro drug metabolism detection

2014 ◽  
Vol 6 (2) ◽  
pp. 025008 ◽  
Author(s):  
Qudus Hamid ◽  
Chengyang Wang ◽  
Yu Zhao ◽  
Jessica Snyder ◽  
Wei Sun
Keyword(s):  
Drug Metabolism ◽  
Microfluidic Chip ◽  
Three Dimensional ◽  
Dimensional Cell

scholarly journals Three-Dimensional Electro-Sonic Flow Focusing Ionization Microfluidic Chip for Mass Spectrometry

Micromachines ◽  
2015 ◽  
Vol 6 (12) ◽  
pp. 1890-1902 ◽  
Author(s):  
Cilong Yu ◽  
Xiang Qian ◽  
Yan Chen ◽  
Quan Yu ◽  
Kai Ni ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Microfluidic Chip ◽  
Three Dimensional ◽  
Flow Focusing ◽  
Sonic Flow

scholarly journals Effect of curing parameters and configuration on the efficacy of ultraviolet light curing self-adhesive masks used for abrasive jet micro-machining and microfluidic device fabrication

2021 ◽  
Author(s):  
Farbod Ahmadzadeh
Keyword(s):  
Microfluidic Chip ◽  
Biomedical Applications ◽  
Uv Light ◽  
Three Dimensional ◽  
Uv Curing ◽  
Device Fabrication ◽  
Flow Focusing ◽  
Three Dimensional Flow ◽  
Dimensional Flow ◽  
Light Curing

Soft lithography techniques has been used widely in the past decade to fabricate microfluidic chips used in biomedical applications. Abrasive jet machining (AJM) has been used to fabricate similar chips using particle erosion mechanisms. This thesis proposes a new technique using a UV light sensitive self-adhesive mask (RapidMask) and AJM to fabricate a three dimensional flow focusing microfluidic chip where the depth of the channel is allowed to vary along the channel length. A detailed characterization of the effect of curing parameters of a UV light curing self-adhesive mask on the resulting feature resolution is reported. Instead of relying on the manufacturer recommended curing parameters which were vaguely described for specific UV curing units, it was found that measured energy density could be used to quantify a recommended cure that is independent of the curing unit. The best achievable pattern on borosilicate glass using RM and AJM was found and reported along with the erosion rates of uncured, cured RM during AJM. A new methodology was introduced to use multiple layers of the RM in order to increase the achievable feature aspect ratio. The results of the RM curing and multiple layer investigation were then used to fabricate a three dimensional flow focusing chip with a varying depth at the focusing junction. The chip was then sealed and tested to demonstrate its capabilities and potential in healthcare and biomedical applications. To the best knowledge of the author, this thesis is the first to report using a double layer RM to fabricate a microfluidic chip using AJM.

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