scholarly journals Reassortant Highly Pathogenic Influenza A H5N2 Virus Containing Gene Segments Related to Eurasian H5N8 in British Columbia, Canada, 2014

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
John Pasick ◽  
Yohannes Berhane ◽  
Tomy Joseph ◽  
Victoria Bowes ◽  
Tamiko Hisanaga ◽  
...  
Keyword(s):  
British Columbia ◽  
Influenza A ◽  
Highly Pathogenic ◽  
H5n2 Virus

scholarly journals Novel Reassortant Highly Pathogenic Avian Influenza A(H5N2) Virus in Broiler Chickens, Egypt

2020 ◽  
Vol 26 (1) ◽  
pp. 129-133 ◽  
Author(s):  
Kareem E. Hassan ◽  
Jacqueline King ◽  
Magdy El-Kady ◽  
Manal Afifi ◽  
Hassanein H. Abozeid ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Broiler Chickens ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza ◽  
H5n2 Virus

scholarly journals First detection of highly pathogenic avian influenza virus in Norway

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Knut Madslien ◽  
Torfinn Moldal ◽  
Britt Gjerset ◽  
Sveinn Gudmundsson ◽  
Arne Follestad ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Wild Birds ◽  
Zoonotic Potential ◽  
Active Monitoring ◽  
Main Hypothesis ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza ◽  
Poultry Farms

Abstract Background Several outbreaks of highly pathogenic avian influenza (HPAI) caused by influenza A virus of subtype H5N8 have been reported in wild birds and poultry in Europe during autumn 2020. Norway is one of the few countries in Europe that had not previously detected HPAI virus, despite widespread active monitoring of both domestic and wild birds since 2005. Results We report detection of HPAI virus subtype H5N8 in a wild pink-footed goose (Anser brachyrhynchus), and several other geese, ducks and a gull, from south-western Norway in November and December 2020. Despite previous reports of low pathogenic avian influenza (LPAI), this constitutes the first detections of HPAI in Norway. Conclusions The mode of introduction is unclear, but a northward migration of infected geese or gulls from Denmark or the Netherlands during the autumn of 2020 is currently our main hypothesis for the introduction of HPAI to Norway. The presence of HPAI in wild birds constitutes a new, and ongoing, threat to the Norwegian poultry industry, and compliance with the improved biosecurity measures on poultry farms should therefore be ensured. [MK1]Finally, although HPAI of subtype H5N8 has been reported to have very low zoonotic potential, this is a reminder that HPAI with greater zoonotic potential in wild birds may pose a threat in the future. [MK1]Updated with a sentence emphasizing the risk HPAI pose to poultry farms, both in the Abstract and in the Conclusion-section in main text, as suggested by Reviewer 1 (#7).

scholarly journals Adjuvanted recombinant hemagglutinin H7 vaccine to highly pathogenic influenza A(H7N9) elicits high and sustained antibody responses in healthy adults

npj Vaccines ◽  
2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Christine M. Oshansky ◽  
◽  
James King ◽  
Di Lu ◽  
James Zhou ◽  
...  
Keyword(s):  
Influenza A ◽  
Study Groups ◽  
Cross Reactivity ◽  
Healthy Adults ◽  
Response Strategy ◽  
Seroprotection Rate ◽  
Highly Pathogenic ◽  
Homologous Virus ◽  
Human Infections ◽  
Epidemic Wave

AbstractAn unprecedented number of human infections with avian influenza A(H7N9) in the fifth epidemic wave during the winter of 2016–2017 in China and their antigenic divergence from the viruses that emerged in 2013 prompted development of updated vaccines for pandemic preparedness. We report on the findings of a clinical study in healthy adults designed to evaluate the safety and immunogenicity of three dose levels of recombinant influenza vaccine derived from highly pathogenic A/Guangdong/17SF003/2016 (H7N9) virus adjuvanted with AS03 or MF59 oil-in water emulsions. Most of the six study groups meet the FDA CBER-specified vaccine licensure criterion of 70% seroprotection rate (SPR) for hemagglutination inhibition antibodies to the homologous virus. A substantial proportion of subjects show high cross-reactivity to antigenically distinct heterologous A(H7N9) viruses from the first epidemic wave of 2013. These results provide critical information to develop a pandemic response strategy and support regulatory requirements for vaccination under Emergency Use Authorization.

scholarly journals Unusually High Mortality in Waterfowl Caused by Highly Pathogenic Avian Influenza A(H5N1) in Bangladesh

2015 ◽  
Vol 64 (1) ◽  
pp. 144-156 ◽  
Author(s):  
N. Haider ◽  
K. Sturm-Ramirez ◽  
S. U. Khan ◽  
M. Z. Rahman ◽  
S. Sarkar ◽  
...  
Keyword(s):  
Avian Influenza ◽  
High Mortality ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza

scholarly journals Pathologic Changes in Wild Birds Infected with Highly Pathogenic Avian Influenza A(H5N8) Viruses, South Korea, 2014

2015 ◽  
Vol 21 (5) ◽  
pp. 775-780 ◽  
Author(s):  
Hye-Ryoung Kim ◽  
Yong-Kuk Kwon ◽  
Il Jang ◽  
Youn-Jeong Lee ◽  
Hyun-Mi Kang ◽  
...  
Keyword(s):  
Avian Influenza ◽  
South Korea ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Wild Birds ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza

scholarly journals Biological characterisation of the emerged highly pathogenic avian influenza (HPAI) A(H7N9) viruses in humans, in mainland China, 2016 to 2017

2017 ◽  
Vol 22 (19) ◽  
Author(s):  
Wenfei Zhu ◽  
Jianfang Zhou ◽  
Zi Li ◽  
Lei Yang ◽  
Xiyan Li ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Mainland China ◽  
H7n9 Virus ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza ◽  
Binding Preference ◽  
Severe Infections ◽  
Epidemic Wave

With no or low virulence in poultry, avian influenza A(H7N9) virus has caused severe infections in humans. In the current fifth epidemic wave, a highly pathogenic avian influenza (HPAI) H7N9 virus emerged. The insertion of four amino acids (KRTA) at the haemagglutinin (HA) cleavage site enabled trypsin-independent infectivity of this virus. Although maintaining dual receptor-binding preference, its HA antigenicity was distinct from low-pathogenic avian influenza A(H7N9). The neuraminidase substitution R292K conferred a multidrug resistance phenotype.

scholarly journals Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity

2017 ◽  
Vol 23 (2) ◽  
pp. 220-231 ◽  
Author(s):  
Hongbo Guo ◽  
Erik de Vries ◽  
Ryan McBride ◽  
Jojanneke Dekkers ◽  
Wenjie Peng ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Influenza A ◽  
Binding Specificity ◽  
Highly Pathogenic ◽  
Receptor Binding Specificity

scholarly journals Infection Risk for Persons Exposed to Highly Pathogenic Avian Influenza A H5 Virus–Infected Birds, United States, December 2014–March 2015

2015 ◽  
Vol 21 (12) ◽  
pp. 2135-2140 ◽  
Author(s):  
Carmen S. Arriola ◽  
Deborah I. Nelson ◽  
Thomas J. Deliberto ◽  
Lenee Blanton ◽  
Krista Kniss ◽  
...  
Keyword(s):  
United States ◽  
Avian Influenza ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Infection Risk ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza

scholarly journals Protection and Virus Shedding of Falcons Vaccinated against Highly Pathogenic Avian Influenza A Virus (H5N1)

2007 ◽  
Vol 13 (11) ◽  
pp. 1667-1674 ◽  
Author(s):  
Michael Lierz ◽  
Hafez M. Hafez ◽  
Robert Klopfleisch ◽  
Dörte Lüschow ◽  
Christine Prusas ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A Virus ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Highly Pathogenic ◽  
Virus Shedding ◽  
Pathogenic Avian Influenza ◽  
Virus H5n1 ◽  
Avian Influenza A Virus
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