Solid-Liquid state diagrams in pharmaceutical lyophilisation: Crystallization of solutes

Author(s):  
Evgenyi Shalaev ◽  
Felix Franks
2021 ◽  
Vol 5 (3) ◽  
Author(s):  
O.V. Kholiavik ◽  
Alexey Nogovitsyn ◽  
Alexey Kravchuk ◽  
Alexey Samoylenko ◽  
Ruslan Boris

Problems. In the process of obtaining a strip in a casting and rolling device, the question arises of combining the process of hot rolling of the solidified material and the process of crystallization of the liquid melt. This makes it possible to implement an efficient technology for producing thin-sheet products. Purpose of the study. Determination of rational parameters for performing mathematical modeling of material behavior during roll casting requires clearly defined recommendations. The material for the rolling process is steel. The starting material was used in solid, solid-liquid and liquid states. Implementation technique. The analysis of the properties of steel was carried out on the basis of the results of experiments obtained at the Physico-Technological Institute of Metals and Alloys of the National Academy of Sciences of Ukraine. To analyze the rheological properties of steel, the dependences of the yield stress for alloyed and carbon steels were used in a certain temperature range. The selected temperature range includes solidus and solid-liquid state of steel, located above 0.8 melting point. Research results. Based on the research results, the analysis of the rheological properties of steel in solid, solid-liquid and liquid states during continuous casting-rolling on rolls was carried out. The use of the obtained dependencies makes it possible to perform mathematical modeling of the deformation and hydrodynamics of the material during continuous casting-rolling of steel strips using roll casting-rolling devices. Conclusions. The constructed dependences, together with studies of the viscosity of steel in the liquid state and the resistance of steel to deformation in the solid state, most fully describe the rheological properties of steels during casting-deformation processes. The obtained dependences will make it possible to implement an ultra-efficient technology for producing thin-sheet rolled products.


1969 ◽  
Vol 2 (7) ◽  
pp. 279-280
Author(s):  
William K. Roots ◽  
Mazin A. H. Kadhim

In electroheat processes used in the metallurgical industries it is often desired to hold metallic charges at a temperature corresponding to their solid/liquid stat? interface. Similar requirements exist in the manufacture of chocolate, wax and similar products. A solid/liquid state sensing transducer has been developed in which a probe is plunged into and withdrawn from the charge. The armature current of the servomotor driving the probe gives information as to the state of the charge. A form of this transducer was developed which gave excellent results in holding metallic charges. The final transducer was well within the accuracy requirements of industrial processes, yet was unsophisticated and could easily be inexpensively constructed.


2006 ◽  
Vol 116-117 ◽  
pp. 626-629 ◽  
Author(s):  
Krzysztof P. Sołek ◽  
Zbigniew Mitura ◽  
Roman Kuziak ◽  
Plato Kapranos

The main purpose of work was to develop a methodology of physical and numerical simulation of the thixocasting processes. For the purpose of the studies an experiment was conducted using a GLEEBLE 3800 simulator. In this work, the GLEEBLE 3800 system was adapted for physical simulation of the processes of light metal alloy forming in the solid-liquid state. The physical simulations of thixoforming processes and characterization of thixotropic materials were supported by computer simulations using ADINA software. The numerical model of thixoforming processes was developed in order to estimate values of the rheological model parameters.


Cryobiology ◽  
1994 ◽  
Vol 31 (4) ◽  
pp. 374-382 ◽  
Author(s):  
E.Yu. Shalaev ◽  
A.N. Kanev

1970 ◽  
Vol 19 (1) ◽  
pp. 78-81
Author(s):  
William K. Roots ◽  
Mazin A. H. Kadhim
Keyword(s):  

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