One-pot aqueous synthesis of composition-tunable near-infrared emitting Cu-doped CdS quantum dots as fluorescence imaging probes in living cells

2012 ◽  
Vol 22 (41) ◽  
pp. 22250 ◽  
Author(s):  
Fei Zhang ◽  
Xi-Wen He ◽  
Wen-You Li ◽  
Yu-Kui Zhang
RSC Advances ◽  
2014 ◽  
Vol 4 (77) ◽  
pp. 41164-41171 ◽  
Author(s):  
Yoshikazu Tsukasaki ◽  
Masatoshi Morimatsu ◽  
Goro Nishimura ◽  
Takao Sakata ◽  
Hidehiro Yasuda ◽  
...  

This paper describes the synthesis and optical properties of PbS/CdS quantum dots for in vivo fluorescence imaging.


2012 ◽  
Vol 258 (18) ◽  
pp. 7181-7187 ◽  
Author(s):  
Yaxin Yu ◽  
Kexin Zhang ◽  
Shuqing Sun

RSC Advances ◽  
2013 ◽  
Vol 3 (43) ◽  
pp. 20959-20969 ◽  
Author(s):  
Rijun Gui ◽  
Xueqin An

A layer-by-layer epitaxial method was developed to synthesize water-soluble, near-infrared (NIR)-emitting type-II core–shell CdTe/CdS quantum dots (QDs) via employing glutathione-capped CdTe QDs as core templates, CdCl2 and thiourea as shell precursors.


Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2544
Author(s):  
Joshua M. Burns ◽  
Elise Shafer ◽  
Raviraj Vankayala ◽  
Vikas Kundra ◽  
Bahman Anvari

Ovarian cancer is the deadliest gynecological cancer. Cytoreductive surgery to remove primary and intraperitoneal tumor deposits remains as the standard therapeutic approach. However, lack of an intraoperative image-guided approach to enable the visualization of all tumors can result in incomplete cytoreduction and recurrence. We engineered nano-sized particles derived from erythrocytes that encapsulate the near infrared (NIR) fluorochrome, indocyanine green, as potential imaging probes for tumor visualization during cytoreductive surgery. Herein, we present the first demonstration of the use of these nanoparticles in conjunction with spatially-modulated illumination (SMI), at spatial frequencies in the range of 0–0.5 mm−1, to fluorescently image intraperitoneal ovarian tumors in mice. Results of our animal studies suggest that the nanoparticles accumulated at higher levels within tumors 24 h post-intraperitoneal injection as compared to various other organs. We demonstrate that, under the imaging specifications reported here, use of these nanoparticles in conjunction with SMI enhances the fluorescence image contrast between intraperitoneal tumors and liver, and between intraperitoneal tumors and spleen by nearly 2.1, and 3.0 times, respectively, at the spatial frequency of 0.2 mm−1 as compared to the contrast values at spatially-uniform (non-modulated) illumination. These results suggest that the combination of erythrocyte-derived NIR nanoparticles and structured illumination provides a promising approach for intraoperative fluorescence imaging of ovarian tumor nodules at enhanced contrast.


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