Antioxidant effect of salidroside and its protective effect against furan-induced hepatocyte damage in mice

2013 ◽  
Vol 4 (5) ◽  
pp. 763 ◽  
Author(s):  
Yuan Yuan ◽  
Si-Jia Wu ◽  
Xin Liu ◽  
Lu-Lu Zhang
Keyword(s):  
Protective Effect ◽  
Antioxidant Effect ◽  
Hepatocyte Damage

Protective effect of allicin against acrylamide-induced hepatocyte damage in vitro and in vivo

2012 ◽  
Vol 50 (9) ◽  
pp. 3306-3312 ◽  
Author(s):  
Lulu Zhang ◽  
Huanjie Zhang ◽  
Yutian Miao ◽  
Sijia Wu ◽  
Haiqing Ye ◽  
...  
Keyword(s):  
Protective Effect ◽  
Hepatocyte Damage

Protective effect of liensinine on periodontitis through its antioxidant effect in mice

2015 ◽  
Vol 58 (6) ◽  
pp. 927-936 ◽  
Author(s):  
Liang Pang ◽  
Kai Zhu ◽  
Xia Feng ◽  
Weiwei Liu ◽  
Deguang Peng ◽  
...  
Keyword(s):  
Protective Effect ◽  
Antioxidant Effect

ANTIOXIDANT EFFECT AND DNA PROTECTIVE EFFECT OF VARIOUS ENZYMATIC EXTRACTS FROM PERILLA FRUTESCENS VAR. CRISPA

2007 ◽  
Vol 14 (4) ◽  
pp. 335-349 ◽  
Author(s):  
EUN-KYUNG KIM ◽  
SEUNG-JAE LEE ◽  
YOU-JIN JEON ◽  
CHANG-BUM AHN ◽  
MIN DONG SONG ◽  
...  
Keyword(s):  
Protective Effect ◽  
Antioxidant Effect ◽  
Perilla Frutescens

Protective Effect of Luminal Uric Acid Against Indomethacin-Induced Enteropathy: Role of Antioxidant Effect and Gut Microbiota

2021 ◽  
Author(s):  
Akinori Wada ◽  
Masaaki Higashiyama ◽  
Chie Kurihara ◽  
Suguru Ito ◽  
Rina Tanemoto ◽  
...  
Keyword(s):  
Uric Acid ◽  
Gut Microbiota ◽  
Protective Effect ◽  
Antioxidant Effect

scholarly journals Medicinal Properties of Flavonoids: الفلافونويدات وخواصها الدوائية

2019 ◽  
Vol 3 (4) ◽  
Author(s):  
Hasan M. H. Muhaisen, Esraa M. M. Ali
Keyword(s):  
Protective Effect ◽  
Folk Medicine ◽  
Epidemiological Studies ◽  
Biological Properties ◽  
Antioxidant Effect ◽  
Present Review ◽  
Isolation And Identification ◽  
Active Constituents ◽  
Antitumour Agents ◽  
Positive Effects

  Flavonoids are ubiquitous in photosynthesizing cells and are commonly found in fruit, vegetables, nuts, seeds, stems, flowers, tea, and honey. Therefore, a significant quantity is consumed in our daily diet. These flavonoids are variously associated with the sensory and nutritional quality of our plant foods. For centuries, preparations containing these compounds as the principal physiologically active constituents have been used to treat human diseases. There has been increasing interest in the research on flavonoids from plant sources because of their versatile health benefits reported in various epidemiological studies. Since flavonoids are directly associated with human dietary ingredients and health, there is need to evaluate structure and function relationship. There have been many bioassay guided searches for cytotoxic antitumour agents in plants especially those known to be used in folk medicine for this purpose. This has led to the isolation and identification of quite a large number of active constituents from all the different flavonoid classes, e.g. catechins, flavans, dihydrochalcones, chalcones, flavanones, dihydro-flavonols, flavones, biflavonoids and flavonol. The purpose of the present review is to discuss recent developments in the biochemistry and medicinal aspects of the flavonoids. Flavonoids have received a lot of interest in scientific research over the past 20 years and have had many beneficial and potential effects. Flavonoids have many great advantages as natural compounds compared to therapeutic agents because many diets are rich in polyphenols and are consumed daily and are easily absorbed in the intestines after ingestion, especially flavonoids, have positive effects on health: antioxidants, lethargy, allergies and bacteria, And cancer. The protective effect of flavonoids is primarily due to its antioxidant effect and inhibition of enzymes. The protective effect of flavonoids from diseases is mainly due to their antioxidant effect. Recent research on the biological properties of flavonoids will therefore be a further subject of the present review.

Protective Effect of Melatonin on Infrarenal Aortic Occlusion: This Effect Is Related to Anti-inflammatory Effect and Antioxidant Effect

Inflammation ◽  
2014 ◽  
Vol 37 (4) ◽  
pp. 1111-1119 ◽  
Author(s):  
Ahmet Ahsen ◽  
Yucel Gonul ◽  
Abdurrahman Genc ◽  
Memnune Sena Ulu ◽  
Murat Yagmurca ◽  
...  
Keyword(s):  
Protective Effect ◽  
Antioxidant Effect ◽  
Aortic Occlusion ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Rho-kinase inhibitor prevents hepatocyte damage in acute liver injury induced by carbon tetrachloride in rats

2007 ◽  
Vol 293 (4) ◽  
pp. G911-G917 ◽  
Author(s):  
Hitoshi Ikeda ◽  
Yukio Kume ◽  
Kazuaki Tejima ◽  
Tomoaki Tomiya ◽  
Takako Nishikawa ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Liver Injury ◽  
Protective Effect ◽  
Kinase Inhibitor ◽  
Acute Liver Injury ◽  
Rho Kinase ◽  
Akt Pathway ◽  
Rho Kinase Inhibitor ◽  
Hepatocyte Damage

A protective effect of Rho-kinase inhibitor on various organ injuries is gaining attention. Regarding liver injury, Rho-kinase inhibitor is reported to prevent carbon tetrachloride (CCl4)- or dimethylnitrosamine-induced liver fibrosis and hepatic ischemia-reperfusion injury in rats. Because Rho-kinase inhibitor not only improved liver fibrosis but also reduced serum alanine aminotransferase (ALT) level in CCl4-induced liver fibrosis, we wondered whether Rho-kinase inhibitor might exert a direct hepatocyte-protective effect. We examined this possibility in acute CCl4 intoxication in rats. Rho-kinase inhibitor, HA-1077, reduced serum alanine ALT level in rats with acute liver injury induced by CCl4 with the improvement of histological damage and the reduction of the number of apoptotic cells. In cultured rat hepatocytes in serum-free condition, HA-1077 reduced apoptosis evaluated by quantitative determination of cytoplasmic histone-associated DNA oligonucleosome fragments with the reduction of caspase-3 activity and the enhancement of Bcl-2 expression. HA-1077 stimulated phosphorylation of Akt, and wortmannin, an inhibitor of phosphatidylinositol 3-kinase (PI3-kinase)/Akt pathway, abrogated the reduction of hepatocyte apoptosis by HA-1077 in vitro. Furthermore, wortmannin abrogated the reduction of serum ALT level by HA-1077 in rats with acute liver injury induced by CCl4, suggesting that the activation of PI3-kinase/Akt pathway may be involved in the hepatocyte-protective effect by Rho-kinase inhibitor in vivo. In conclusion, Rho-kinase inhibitor prevented hepatocyte damage in acute liver injury induced by CCl4 in rats and merits consideration as a hepatocyte-protective agent in liver injury, considering its direct antiapoptotic effect on hepatocytes in vitro.

Protective effect of irisolidone, a metabolite of kakkalide, against hydrogen peroxide induced cell damage via antioxidant effect

2008 ◽  
Vol 16 (3) ◽  
pp. 1133-1141 ◽  
Author(s):  
Kyoung Ah Kang ◽  
Rui Zhang ◽  
Mei Jing Piao ◽  
Dong Ok Ko ◽  
Zhi Hong Wang ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Protective Effect ◽  
Cell Damage ◽  
Antioxidant Effect

Protective effect of the extracts from Cnidium officinale against oxidative damage induced by hydrogen peroxide via antioxidant effect

2009 ◽  
Vol 47 (3) ◽  
pp. 525-529 ◽  
Author(s):  
Jin Boo Jeong ◽  
Jae Ho Park ◽  
Hee Kyeong Lee ◽  
So Yeong Ju ◽  
Se Chul Hong ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Oxidative Damage ◽  
Protective Effect ◽  
Antioxidant Effect ◽  
Cnidium Officinale

Protective effect of C-phycocyanin against carbon tetrachloride-induced hepatocyte damage in vitro and in vivo

2010 ◽  
Vol 185 (2) ◽  
pp. 94-100 ◽  
Author(s):  
Yu Ou ◽  
Shan Zheng ◽  
Lin Lin ◽  
Qizhou Jiang ◽  
Xuegan Yang
Keyword(s):  
Carbon Tetrachloride ◽  
Protective Effect ◽  
Hepatocyte Damage
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