A water-soluble sulfonate-BODIPY based fluorescent probe for selective detection of HOCl/OCl−in aqueous media

The Analyst ◽  
2014 ◽  
Vol 139 (12) ◽  
pp. 2986-2989 ◽  
Author(s):  
Jiyoung Kim ◽  
Youngmi Kim

A water-soluble sulfonate-BODIPY dye1was developed for the selective detection of HOCl/OCl−in aqueous buffer solution. The probe, which displays extremely weak fluorescence owing to efficient photoinduced electron transfer (PeT) from the pendant catechol donor, responds to HOCl/OCl−through a dramatic enhancement of its fluorescence intensity.

2016 ◽  
Vol 52 (51) ◽  
pp. 7982-7985 ◽  
Author(s):  
Lijuan Liang ◽  
Chang Liu ◽  
Xiaojie Jiao ◽  
Liancheng Zhao ◽  
Xianshun Zeng

A probe based on the phenothiazine–acridine orange conjugate (Ptz–AO) has been designed and synthesized for the sensitive and selective detection of HOCl.


The Analyst ◽  
2019 ◽  
Vol 144 (4) ◽  
pp. 1260-1264 ◽  
Author(s):  
Yannan Li ◽  
Li Yang ◽  
Mengqi Du ◽  
Guanjun Chang

A novel fluorescent probe for Pd2+ based on the BODIPY fluorophore exploiting the PET (Photoinduced Electron Transfer) mechanism was designed and successfully synthesized.


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Ming La ◽  
Yuanqiang Hao ◽  
Zhaoyang Wang ◽  
Guo-Cheng Han ◽  
Lingbo Qu

A water-soluble fluorescent probe (C-GGH) was used for the highly sensitive and selective detection of cyanide (CN−) in aqueous media based on the displacement strategy. Due to the presence of the recognition unit GGH (Gly-Gly-His), the probeC-GGH can coordinate with Cu2+and consequently display ON-OFF type fluorescence response. Furthermore, thein situformed nonfluorescentC-GGH-Cu2+complex can act as an effective OFF-ON type fluorescent probe for sensing CN−anion. Due to the strong binding affinity of CN−to Cu2+, CN−can extract Cu2+fromC-GGH-Cu2+complex, leading to the release ofC-GGH and the recovery of fluorescent emission of the system. The probeC-GGH-Cu2+allowed detection of CN−in aqueous solution with a LOD (limit of detection) of 0.017 μmol/L which is much lower than the maximum contaminant level (1.9 μmol/L) for CN−in drinking water set by the WHO (World Health Organization). The probe also displayed excellent specificity for CN−towards other anions, including F−, Cl−, Br−, I−, SCN−,PO43-,N3-,NO3-, AcO−,SO42-, andCO32-.


2018 ◽  
Vol 15 (1) ◽  
pp. 47-55
Author(s):  
Xuebing Li ◽  
Haifen Yang ◽  
Ning Wang ◽  
Tijian Sun ◽  
Wei Bian ◽  
...  

Background: Morin has many pharmacological functions including antioxidant, anticancer, anti-inflammatory, and antibacterial effects. It is commonly used in the treatment of antiviral infection, gastropathy, coronary heart disease and hepatitis B in clinic. However, researches have shown that morin is likely to show prooxidative effects on the cells when the amount of treatment is at high dose, leading to the decrease of intracellular ATP levels and the increase of necrosis process. Therefore, it is necessary to determine the concentration of morin in biologic samples. Method: Novel water-soluble and green nitrogen and sulfur co-doped carbon dots (NSCDs) were prepared by a microwave heating process with citric acid and L-cysteine. The fluorescence spectra were collected at an excitation wavelength of 350 nm when solutions of NSCDs were mixed with various concentrations of morin. Results: The as-prepared NSCDs were characterized by transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The fluorescence intensity of NSCDs decreased significantly with the increase of morin concentration. The fluorescence intensity of NSCDs displayed a linear response to morin in the concentration 0.10-30 μM with a low detection limit of 56 nM. The proposed fluorescent probe was applied to analysis of morin in human body fluids with recoveries of 98.0-102%. Conclusion: NSCDs were prepared by a microwave heating process. The present analytical method is sensitive to morin. The quenching process between NSCDs and morin is attributed to the static quenching. In addition, the cellular toxicity on HeLa cells indicated that the as-prepared NSCDs fluorescent probe does not show obvious cytotoxicity in cell imaging. Our proposed method possibly opens up a rapid and nontoxic way for preparing heteroatom doped carbon dots with a broad application prospect.


Author(s):  
Keiichi Fujimoto ◽  
Hayato Takeuchi ◽  
Tomoyuki Takaku ◽  
Jun Abe ◽  
Koichiro Harada

1999 ◽  
Vol 69 (5) ◽  
pp. 513-516 ◽  
Author(s):  
Hai-Feng Ji ◽  
Reza Dabestani ◽  
Gilbert M. Brownxy ◽  
Robert L. Hettich

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