A label-free activatable aptamer probe for colorimetric detection of cancer cells based on binding-triggered in situ catalysis of split DNAzyme

The Analyst ◽  
2014 ◽  
Vol 139 (17) ◽  
pp. 4181-4184 ◽  
Author(s):  
Hui Shi ◽  
Duo Li ◽  
Fengzhou Xu ◽  
Xiaoxiao He ◽  
Kemin Wang ◽  
...  
Keyword(s):  
Cell Surface ◽  
Cancer Cells ◽  
Living Cell ◽  
Colorimetric Detection ◽  
Cell Detection ◽  
Label Free ◽  
Aptamer Probe ◽  
Cancer Cell Detection ◽  
In Situ Catalysis

A label-free activatable aptamer probe was developed for cancer cell detection through recognition-switched split DNAzyme activity on a living cell surface.

Tumor cell-specific split aptamers: target-driven and temperature-controlled self-assembly on the living cell surface

2016 ◽  
Vol 52 (7) ◽  
pp. 1482-1485 ◽  
Author(s):  
Jinlu Tang ◽  
Hui Shi ◽  
Xiaoxiao He ◽  
Yanli Lei ◽  
Qiuping Guo ◽  
...  
Keyword(s):  
Cell Surface ◽  
Tumor Cell ◽  
Self Assembly ◽  
Living Cell ◽  
Cell Detection ◽  
Temperature Controlled ◽  
Aptamer Probe ◽  
Assembly Performance

A novel tumor cell-specific split aptamer probe was developed with target-driven and temperature-controlled self-assembly performance for cell detection and manipulation.

In Situ Growth of Porous Platinum Nanoparticles on Graphene Oxide for Colorimetric Detection of Cancer Cells

2014 ◽  
Vol 86 (5) ◽  
pp. 2711-2718 ◽  
Author(s):  
Ling-Na Zhang ◽  
Hao-Hua Deng ◽  
Feng-Lin Lin ◽  
Xiong-Wei Xu ◽  
Shao-Huang Weng ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Cancer Cells ◽  
Platinum Nanoparticles ◽  
Colorimetric Detection ◽  
In Situ Growth

scholarly journals Label-Free Cancer Cell Detection with Impedimetric Transducers

2009 ◽  
Vol 81 (24) ◽  
pp. 10167-10171 ◽  
Author(s):  
Roberto de la Rica ◽  
Sebastian Thompson ◽  
Antonio Baldi ◽  
Cesar Fernandez-Sanchez ◽  
Charles Michael Drain ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Cell Detection ◽  
Label Free ◽  
Free Cancer Cell ◽  
Cancer Cell Detection

Interaction of Positively Charged Gold Nanoparticles with Cancer Cells Monitored by an in Situ Label-Free Optical Biosensor and Transmission Electron Microscopy

2018 ◽  
Vol 10 (32) ◽  
pp. 26841-26850 ◽  
Author(s):  
Beatrix Peter ◽  
Istvan Lagzi ◽  
Satoshi Teraji ◽  
Hideyuki Nakanishi ◽  
Laszlo Cervenak ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Optical Biosensor ◽  
Label Free ◽  
Transmission Electron ◽  
Positively Charged Gold Nanoparticles ◽  
Positively Charged

scholarly journals In situ recognition of cell-surface glycans and targeted imaging of cancer cells

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Xiao-Ding Xu ◽  
Han Cheng ◽  
Wei-Hai Chen ◽  
Si-Xue Cheng ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Cell Surface ◽  
Cancer Cells ◽  
Targeted Imaging ◽  
Cell Surface Glycans

scholarly journals Design of MEMS-based Microfludic Channel to Detect Cancer Cells in Blood

2020 ◽  
Vol 11 (1) ◽  
pp. 561-566
Author(s):  
Syed Shameem ◽  
RamaKrishna T V ◽  
Sahithi M ◽  
Rohitha B ◽  
Keerthana J ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cancer Cell ◽  
Early Stage ◽  
Microfluidic Channel ◽  
Cell Detection ◽  
Malignant Growth ◽  
Simple Manner ◽  
Abnormal Cells ◽  
Mass Displacement ◽  
Cancer Cell Detection

Cancer refers to any of countless infections characterized by the development of abnormal cells that divide uncontrollably and can invade and destroy normal body tissue. Malignant growth frequently can spread all through your body. Cancer is the second driving reason for death on the planet. In this paper, we propose to found a H-cell to screen carcinogenic cells in a given sample of blood based on the principle of diffusion. This model incorporates the planning of a MEMS-based microfluidic channel to screen and recognize different cells depending on the size and various characteristics of the cells. Some of the methods which are implemented not efficient models for cancer cells detection in blood. The mass, displacement technique has been implemented in this investigation for cancer cell detection, with the help of this achieves the accuracy and better throughput. One cancer cell contains = 1.70371e-24 mass, such that with a weight of this formula, find out the total no of cells in the blood. This is the best method compared to existed methods. Using this count, the weight has been calculate early-stage cancer and treatment with a simple manner, CTCs in the blood is the un potential matter for health, H-cells have been measured with proposed weight and force technique such that in this investigation also calculate the healthy and cancer cells also. Finally, using this methodology achieves 93.58% accuracy, 0.00124 MSE. These are very good results compared to conventional methods.

Ultrasensitive U-shaped fiber optic LSPR cytosensing for label-free and in situ evaluation of cell surface N-glycan expression

2019 ◽  
Vol 284 ◽  
pp. 582-588 ◽  
Author(s):  
Zewei Luo ◽  
Yimin Wang ◽  
Ya Xu ◽  
Xu Wang ◽  
Zhijun Huang ◽  
...  
Keyword(s):  
Cell Surface ◽  
Fiber Optic ◽  
Label Free

scholarly journals In Situ Synthesis of an Aptamer‐Based Polyvalent Antibody Mimic on the Cell Surface for Enhanced Interactions between Immune and Cancer Cells

2020 ◽  
Vol 59 (29) ◽  
pp. 11892-11897 ◽  
Author(s):  
Peng Shi ◽  
Xuelin Wang ◽  
Brandon Davis ◽  
James Coyne ◽  
Cheng Dong ◽  
...  
Keyword(s):  
Cell Surface ◽  
Cancer Cells ◽  
In Situ Synthesis

Mannosyl electrochemical impedance cytosensor for label-free MDA-MB-231 cancer cell detection

2018 ◽  
Vol 116 ◽  
pp. 100-107 ◽  
Author(s):  
Yi-Hsuan Tang ◽  
Han-Chen Lin ◽  
Chiao-Ling Lai ◽  
Po-Yu Chen ◽  
Chian-Hui Lai
Keyword(s):  
Cancer Cell ◽  
Electrochemical Impedance ◽  
Cell Detection ◽  
Label Free ◽  
Cancer Cell Detection
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