A lithium-rich composite metal oxide used as a SALDI-MS matrix for the determination of small biomolecules

2014 ◽  
Vol 50 (97) ◽  
pp. 15397-15399 ◽  
Author(s):  
Ze Li ◽  
Yi-Wei Zhang ◽  
Yue-Long Xin ◽  
Yu Bai ◽  
Heng-Hui Zhou ◽  
...  

A lithium-rich composite metal oxide material used as a SALDI matrix for high throughput analysis of small molecules.

2019 ◽  
Vol 11 (28) ◽  
pp. 3532-3537 ◽  
Author(s):  
Limin Guo

Microplate based assays have advantages such as rapid detection and high throughput analysis.


Metabolites ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 789
Author(s):  
Yuzhu Guo ◽  
Michael Forbush ◽  
Thomas R. Covey ◽  
Lucien Ghislain ◽  
Chang Liu

Acoustic ejection mass spectrometry is a novel high-throughput analytical technology that delivers high reproducibility without carryover observed. It eliminates the chromatography step used to separate analytes from matrix components. Fully-automated liquid–liquid extraction is widely used for sample cleanup, especially in high-throughput applications. We introduce a workflow for direct AEMS analysis from phase-separated liquid samples and explore high-throughput analysis from complex matrices. We demonstrate the quantitative determination of fentanyl from urine using this two-phase AEMS approach, with a LOD lower than 1 ng/mL, quantitation precision of 15%, and accuracy better than ±10% over the range of evaluation (1–100 ng/mL). This workflow offers simplified sample preparation and higher analytical throughput for some bioanalytical applications, in comparison to an LC-MS based approach.


2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Ezel Boyacı ◽  
Barbara Bojko ◽  
Nathaly Reyes-Garcés ◽  
Justen J. Poole ◽  
Germán Augusto Gómez-Ríos ◽  
...  

2015 ◽  
Vol 11 (4) ◽  
pp. 233-238 ◽  
Author(s):  
Luciano Cardoso ◽  
Suellen Cordeiro ◽  
Marcio Fronza ◽  
Denise Endringer ◽  
Tadeu de Andrade ◽  
...  

Author(s):  
Ruoxing Lei ◽  
Erin A. Akins ◽  
Kelly C. Y. Wong ◽  
Nicole A. Repina ◽  
Kayla J. Wolf ◽  
...  

The Analyst ◽  
2021 ◽  
Author(s):  
Jiawei Qi ◽  
Pinhua Rao ◽  
Lele Wang ◽  
Li Xu ◽  
Yanli Wen ◽  
...  

Pattern recognition, also called “array sensing” is a recognition strategy with a wide and expandable analysis range, based on the high-throughput analysis data. In this work, we constructed a sensor...


Author(s):  
Xiaojia Jiang ◽  
Mingsong Zang ◽  
Fei Li ◽  
Chunxi Hou ◽  
Quan Luo ◽  
...  

Biological nanopore-based techniques have attracted more and more attention recently in the field of single-molecule detection, because they allow the real-time, sensitive, high-throughput analysis. Herein, we report an engineered biological...


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