A large-scale superhydrophobic surface-enhanced Raman scattering (SERS) platform fabricated via capillary force lithography and assembly of Ag nanocubes for ultratrace molecular sensing

2014 ◽  
Vol 16 (48) ◽  
pp. 26983-26990 ◽  
Author(s):  
Joel Ming Rui Tan ◽  
Justina Jiexin Ruan ◽  
Hiang Kwee Lee ◽  
In Yee Phang ◽  
Xing Yi Ling
Keyword(s):  
Detection Limit ◽  
High Throughput ◽  
Superhydrophobic Surface ◽  
Large Scale ◽  
Molecular Sensing ◽  
M 10 ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Capillary Force Lithography

A high-throughput fabrication of a stable and uniform superhydrophobic SERS platform is demonstrated. It is able to detect trace molecules at ultra-low detection limit of 10−17 M (10 aM) using just 4 μL of analyte solutions.

scholarly journals Large-Scale Fabrication of Ultrasensitive and Uniform Surface-Enhanced Raman Scattering Substrates for the Trace Detection of Pesticides

Nanomaterials ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. 520 ◽  
Author(s):  
Jia Zhu ◽  
Guanzhou Lin ◽  
Meizhang Wu ◽  
Zhuojie Chen ◽  
Peimin Lu ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Large Scale ◽  
Capillary Flow ◽  
Surface Enhanced Raman Scattering ◽  
Ag Nps ◽  
Uniform Size ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Technology transfer from laboratory into practical application needs to meet the demands of economic viability and operational simplicity. This paper reports a simple and convenient strategy to fabricate large-scale and ultrasensitive surface-enhanced Raman scattering (SERS) substrates. In this strategy, no toxic chemicals or sophisticated instruments are required to fabricate the SERS substrates. On one hand, Ag nanoparticles (NPs) with relatively uniform size were synthesized using the modified Tollens method, which employs an ultra-low concentration of Ag+ and excessive amounts of glucose as a reducing agent. On the other hand, when a drop of the colloidal Ag NPs dries on a horizontal solid surface, the droplet becomes ropy, turns into a layered structure under gravity, and hardens. During evaporation, capillary flow was burdened by viscidity resistance from the ropy glucose solution. Thus, the coffee-ring effect is eliminated, leading to a uniform deposition of Ag NPs. With this method, flat Ag NPs-based SERS active films were formed in array-well plates defined by hole-shaped polydimethylsiloxane (PDMS) structures bonded on glass substrates, which were made for convenient detection. The strong SERS activity of these substrates allowed us to reach detection limits down to 10−14 M of Rhodamine 6 G and 10−10 M of thiram (pesticide).

Large-scale Ag nanoislands stabilized by a magnetron-sputtered polytetrafluoroethylene film as substrates for highly sensitive and reproducible surface-enhanced Raman scattering (SERS)

2015 ◽  
Vol 3 (43) ◽  
pp. 11478-11485 ◽  
Author(s):  
Martin Šubr ◽  
Martin Petr ◽  
Ondřej Kylián ◽  
Jiří Kratochvíl ◽  
Marek Procházka
Keyword(s):  
Raman Scattering ◽  
High Stability ◽  
Large Scale ◽  
Surface Enhanced Raman Scattering ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Polytetrafluoroethylene Film

Cheap and repeatable fabrication of large-scale Ag nanostructures with high stability, sensitivity and spectral reproducibility for SERS.

Bacteria encapsulation and rapid antibiotic susceptibility test using a microfluidic microwell device integrating surface-enhanced Raman scattering

Lab on a Chip ◽  
2020 ◽  
Vol 20 (14) ◽  
pp. 2520-2528 ◽  
Author(s):  
Hsiu-Kang Huang ◽  
Ho-Wen Cheng ◽  
Cheng-Chieh Liao ◽  
Shang-Jyun Lin ◽  
Yi-Zih Chen ◽  
...  
Keyword(s):  
Raman Scattering ◽  
High Throughput ◽  
Antibiotic Susceptibility ◽  
Susceptibility Test ◽  
Sers Substrate ◽  
Antibiotic Susceptibility Test ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

We developed a microfluidic microwell device integrating SERS substrate for an efficient bacteria encapsulation and enrichment followed by in situ SERS-AST measurement, which can potentially apply for high throughput and multi-parallel AST.

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