Cytochrome C capped mesoporous silica nanocarriers for pH-sensitive and sustained drug release

2014 ◽  
Vol 2 (27) ◽  
pp. 4356-4362 ◽  
Author(s):  
Yuxia Tang ◽  
Zhaogang Teng ◽  
Ying Liu ◽  
Ying Tian ◽  
Jing Sun ◽  
...  

Drug nanocarriers with pH-sensitive and sustained drug release properties were constructed by using cytochrome C as a pore blocker to achieve high therapeutic efficacy for cancer.

RSC Advances ◽  
2018 ◽  
Vol 8 (65) ◽  
pp. 37433-37440 ◽  
Author(s):  
Huicong Zhang ◽  
Xuandong Wang ◽  
Peiyuan Wang ◽  
Rong Liu ◽  
Xuemei Hou ◽  
...  

Polydopamine-doped mesoporous silica nanocomposites (PMSNs) were controllably synthesized by a one-pot approach. They were demonstrated to be good biodegradability, pH-responsive drug release and targeting synergistic chemo-photothermal therapy.


2014 ◽  
Vol 8 (4) ◽  
pp. 179-183 ◽  
Author(s):  
Di Xiang ◽  
Huiming Lin ◽  
Wei Guo ◽  
Jie Ma ◽  
Liru Cui ◽  
...  

2016 ◽  
Vol 7 (7) ◽  
pp. 1475-1485 ◽  
Author(s):  
Panayiotis Bilalis ◽  
Leto-A. Tziveleka ◽  
Spyridon Varlas ◽  
Hermis Iatrou

Mesoporous silica nanoparticles (MSNs) bearing poly(l-histidine)-grafted nanogates were prepared by surface-initiated ROP. The obtained polypeptide-functionalized MSNs were used as smart pH-responsive nanocarriers for controlled drug release applications.


Nanoscale ◽  
2015 ◽  
Vol 7 (21) ◽  
pp. 9497-9504 ◽  
Author(s):  
Devleena Samanta ◽  
Jana L. Meiser ◽  
Richard N. Zare

Charged drug molecules from nanoparticles are released by changing the pH of the surroundings and fine-tuned by adding appropriate amphiphiles.


2015 ◽  
Vol 2015 (13) ◽  
pp. 2277-2284 ◽  
Author(s):  
Ting Zhang ◽  
Zeyang Ding ◽  
Huiming Lin ◽  
Liru Cui ◽  
Chunyu Yang ◽  
...  

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